Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Georg Rast"'
Publikováno v:
Cells, Vol 10, Iss 12, p 3370 (2021)
Subtype-specific human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are promising tools, e.g., to assess the potential of drugs to cause chronotropic effects (nodal hiPSC-CMs), atrial fibrillation (atrial hiPSC-CMs), or ventricula
Externí odkaz:
https://doaj.org/article/67feda51c88a4a5f8455d72bbae1fb09
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221763 (2019)
We compared a published computational model of the action potential of a specific type of human induced pluripotent stem cell -derived cardiomyocytes (hiPSC-CM) with experimental field potential data with regard to their inter-beat interval and the d
Externí odkaz:
https://doaj.org/article/011be1e24cf3433ca21dfbf9cce6728b
Autor:
Stefan Just, Bertrand L Chenard, Angelo Ceci, Timothy Strassmaier, Jayhong A Chong, Nathaniel T Blair, Randall J Gallaschun, Donato Del Camino, Susan Cantin, Marc D'Amours, Christian Eickmeier, Christopher M Fanger, Carsten Hecker, David P Hessler, Bastian Hengerer, Katja S Kroker, Sam Malekiani, Robert Mihalek, Joseph McLaughlin, Georg Rast, JoAnn Witek, Achim Sauer, Christopher R Pryce, Magdalene M Moran
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191225 (2018)
Forty million adults in the US suffer from anxiety disorders, making these the most common forms of mental illness. Transient receptor potential channel canonical subfamily (TRPC) members 4 and 5 are non-selective cation channels highly expressed in
Externí odkaz:
https://doaj.org/article/d155ef5931834a199fead5964ba61d05
Autor:
Christiane Schulz‐Zunkel, Carolin Seele‐Dilbat, Christine Anlanger, Martina Baborowski, Elisabeth Bondar‐Kunze, Mario Brauns, Cedric M. Gapinski, Ralf Gründling, Christina von Haaren, Thomas Hein, Klaus Henle, Frank W. Junge, Hans. D. Kasperidus, Katinka Koll, Lena Kretz, Georg Rast, Ingo Schnauder, Mathias Scholz, Heiko Schrenner, Agnieszka Sendek, Claudia Sprössig, Claudia Nogueira Tavares, Michael Vieweg, Wolf Tümpling, Markus Weitere, Christian Wirth, Tobias Wunsch, Frank Dziock
Publikováno v:
International Review of Hydrobiology
Publikováno v:
Wasser und Abfall. 23:19-22
Publikováno v:
Cells, Vol 10, Iss 3370, p 3370 (2021)
Cells
Cells; Volume 10; Issue 12; Pages: 3370
Cells
Cells; Volume 10; Issue 12; Pages: 3370
Subtype-specific human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are promising tools, e.g., to assess the potential of drugs to cause chronotropic effects (nodal hiPSC-CMs), atrial fibrillation (atrial hiPSC-CMs), or ventricula
Publikováno v:
WASSERWIRTSCHAFT. 109:54-59
IntroductionHuman induced pluripotent stem cell (hiPSC)-derived cardiomyocytes are being evaluated for their use in pharmacological and toxicological testing, particularly for electrophysiological side effects. However, little is known about the comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b303fb322902dd6ce780ff33f1a83954
Autor:
Donato del Camino, Matthew R. Netherton, David P. Hessler, David A. Kass, Lynn Pantages, Grace K. Muller, Julia F. Doerner, Hu Sheng Qian, Jayhong A. Chong, Mark J. Ranek, Angela Berry, Mary McFarland, Nan Zheng, Jay J. Kuo, Djahida Bedja, Sumita Mishra, Steven M. Weldon, Guangshuo Zhu, Nathaniel T. Blair, Hong Bian, Magdalene M. Moran, Chris Sarko, Steven S. Pullen, Damian Matera, Diane Wong, Brian L. Lin, Xiaoguang Zhen, Achim Sauer, Georg Rast, Svetlana Zeveleva
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(20)
Transient receptor potential canonical type 6 (TRPC6) is a nonselective receptor-operated cation channel that regulates reactive fibrosis and growth signaling. Increased TRPC6 activity from enhanced gene expression or gain-of-function mutations contr
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 82:74-82
Introduction Field potential duration in human pluripotent stem cell (hiPSC)-derived cardiomyocytes is discussed as parameter for the assessment of drug-induced delayed repolarization. In spontaneously beating hiPSC-derived cardiomyocytes field poten