Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Georg R. Zoidl"'
Autor:
Cherie A. Brown-Panton, Shiva Sabour, Georg S. O. Zoidl, Christiane Zoidl, Nima Tabatabaei, Georg R. Zoidl
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The zebrafish is a powerful model to investigate the developmental roles of electrical synapses because many signaling pathways that regulate the development of the nervous system are highly conserved from fish to humans. Here, we provide evidence li
Externí odkaz:
https://doaj.org/article/4e88344ea87b483b979612b7cbbd219c
Autor:
Paige Whyte-Fagundes, Daria Taskina, Nickie Safarian, Christiane Zoidl, Peter L. Carlen, Logan W. Donaldson, Georg R. Zoidl
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
The Panx1a and Panx1b (pannexin) ATP release channels exhibit pro- and anti-convulsant effects, respectively, in a zebrafish model, providing further insight into the role of pannexins in seizure development.
Externí odkaz:
https://doaj.org/article/c069c6db042d434194c16d77fdf6fa83
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Siu et al use FRET imaging in neuronal cell lines to explore the interplay between the gap junction channel protein Connexin-36 (Cx36) and NMDA receptor and Pannexin 1-mediated calcium signaling. They demonstrate that an increase in intracellular cal
Externí odkaz:
https://doaj.org/article/5c1a64775f944aa7933d31f56d812d15
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11750 (2021)
Pannexin1 (Panx1) can form ATP-permeable channels that play roles in the physiology of the visual system. In the zebrafish two ohnologs of Panx1, Panx1a and Panx1b, have unique and shared channel properties and tissue expression patterns. Panx1a chan
Externí odkaz:
https://doaj.org/article/52ed0b6f04334cf39a4dd44efbe0de5c
Autor:
Stephan Tetenborg, Shubhash Chandra Yadav, Bianca Brüggen, Georg R. Zoidl, Sheriar G. Hormuzdi, Hannah Monyer, Geeske M. van Woerden, Ulrike Janssen-Bienhold, Karin Dedek
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neuronal gap junctions formed by connexin36 (Cx36) and chemical synapses share striking similarities in terms of plasticity. Ca2+/calmodulin-dependent protein kinase II (CaMKII), an enzyme known to induce memory formation at chemical synapses, has re
Externí odkaz:
https://doaj.org/article/3434a6227aca4eea89744ac97daeb69e
Autor:
Georg R. Zoidl, David C. Spray
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4473 (2021)
Anatomical and electrophysiological evidence that gap junctions and electrical coupling occur between neurons was initially confined to invertebrates and nonmammals and was thought to be a primitive form of synaptic transmission. More recent studies
Externí odkaz:
https://doaj.org/article/247b8955d5ed4c2daf00fd162a3ef663
Autor:
Mark S. Aquilino, Paige Whyte-Fagundes, Mark K. Lukewich, Liang Zhang, Berj L. Bardakjian, Georg R. Zoidl, Peter L. Carlen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7510 (2020)
Objective: Pannexin-1 (Panx1) is suspected of having a critical role in modulating neuronal excitability and acute neurological insults. Herein, we assess the changes in behavioral and electrophysiological markers of excitability associated with Panx
Externí odkaz:
https://doaj.org/article/893c8c86ed9b4e44ae0a705c3a74ee1b
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5401 (2020)
The gap junctional protein connexin 36 (Cx36) has been co-purified with the lipid raft protein caveolin-1 (Cav-1). The relevance of an interaction between the two proteins is unknown. In this study, we explored the significance of Cav-1 interaction i
Externí odkaz:
https://doaj.org/article/ce1bcf6d948c4559a00b83c01b5b15c5
Multi-phenotypic screening of multiple zebrafish larvae plays an important role in enhancing the quality and speed of biological assays. Many microfluidic platforms have been presented for zebrafish phenotypic assays, but multi-organ screening of mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06e12a99639627c694b1117aafef75c
https://doi.org/10.22541/au.165346210.08721516/v1
https://doi.org/10.22541/au.165346210.08721516/v1
Publikováno v:
Biotechnology journalREFERENCES. 17(6)
Electrical stimulation of brain or muscle activities has gained attention for studying the molecular and cellular mechanisms involved in electric-induced responses. We recently showed zebrafish's response to electricity. Here, we hypothesized that th