Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Georg Pall"'
Autor:
Stefan Koeck, Arno Amann, Johan Kern, Marit Zwierzina, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Finn Mildner, Martina Sykora, Susanne Sprung, Hubert Hackl, Florian Augustin, Hubert T. Maier, Andreas Pircher, Georg Pall, Dominik Wolf, Gabriele Gamerith
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTCancer associated fibroblasts (CAF) are known to orchestrate multiple components of the tumor microenvironment, whereas the influence of the whole stromal-fibroblast compartment is less understood. Here, an extended stromal fibroblast signatu
Externí odkaz:
https://doaj.org/article/b8859450d2444344a0b717d8fca9bf03
Autor:
Oliver Illini, Hannah Fabikan, Aurélie Swalduz, Anders Vikström, Dagmar Krenbek, Michael Schumacher, Elizabeth Dudnik, Michael Studnicka, Ronny Öhman, Robert Wurm, Luciano Wannesson, Nir Peled, Waleed Kian, Jair Bar, Sameh Daher, Alfredo Addeo, Ofer Rotem, Georg Pall, Alona Zer, Akram Saad, Tanja Cufer, Hadas Gantz Sorotsky, Sayed M. S. Hashemi, Katja Mohorcic, Ronen Stoff, Yulia Rovitsky, Shoshana Keren-Rosenberg, Thomas Winder, Christoph Weinlinger, Arschang Valipour, Maximilian J. Hochmair
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Patients with non-small cell lung cancer (NSCLC) presenting with mesenchymal–epithelial transition ( MET ) exon 14 skipping mutation have an unfavorable prognosis with standard treatments. Capmatinib is a selective MET inhibitor, which
Externí odkaz:
https://doaj.org/article/0bbcd42c11e74cbfb91361945db11f28
Autor:
Oliver Illini, Maximilian Johannes Hochmair, Hannah Fabikan, Christoph Weinlinger, Amanda Tufman, Aurélie Swalduz, Kristina Lamberg, Sayed M. S. Hashemi, Florian Huemer, Anders Vikström, Martin Wermke, Gudrun Absenger, Alfredo Addeo, Shantanu Banerji, Antonio Calles, Stephen Clarke, Massimo Di Maio, Alice Durand, Michaël Duruisseaux, Malinda Itchins, Okko-Sakari Kääränien, Florian Krenn, Eckart Laack, Adrianus Johannes de Langen, Katja Mohorcic, Georg Pall, Antonio Passaro, Gerald Prager, Achim Rittmeyer, Jeffrey Rothenstein, Michael Schumacher, Ewald Wöll, Arschang Valipour
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Introduction: Rearranged during transfection (RET) gene fusions are rare genetic drivers in non-small cell lung cancer (NSCLC). Selective RET-inhibitors such as selpercatinib have shown therapeutic activity in early clinical trials; however, their ef
Externí odkaz:
https://doaj.org/article/fa3f18a7c5a247f2bb673138b510d84e
Autor:
Alexandros Papachristofilou, Madeleine M. Hipp, Ute Klinkhardt, Martin Früh, Martin Sebastian, Christian Weiss, Miklos Pless, Richard Cathomas, Wolfgang Hilbe, Georg Pall, Thomas Wehler, Jürgen Alt, Helge Bischoff, Michael Geißler, Frank Griesinger, Karl-Josef Kallen, Mariola Fotin-Mleczek, Andreas Schröder, Birgit Scheel, Anke Muth, Tobias Seibel, Claudia Stosnach, Fatma Doener, Henoch S. Hong, Sven D. Koch, Ulrike Gnad-Vogt, Alfred Zippelius
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Preclinical studies demonstrate synergism between cancer immunotherapy and local radiation, enhancing anti-tumor effects and promoting immune responses. BI1361849 (CV9202) is an active cancer immunotherapeutic comprising protamine
Externí odkaz:
https://doaj.org/article/99e04455f1444be88b66a788433ed6e0
Autor:
Wolfgang Hilbe, Georg Pall, Florian Kocher, Andreas Pircher, August Zabernigg, Thomas Schmid, Michael Schumacher, Herbert Jamnig, Michael Fiegl, Anne Gächter, Martin Freund, Dorota Kendler, Claudia Manzl, Bettina Zelger, Helmut Popper, Ewald Wöll
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125364 (2015)
Different strategies for neoadjuvant chemotherapy in patients with early stage NSCLC have already been evaluated. The aim of this study was to evaluate the tolerability and efficacy of a chemoimmunotherapy when limited to two cycles.Between 01/2007 a
Externí odkaz:
https://doaj.org/article/3c68a99779f64d26b8b8caa0f2f9210f
Autor:
SANDRO M. WAGNER, TERESA MAGNES, THOMAS MELCHARDT, DOMINIK KIEM, LUKAS WEISS, DANIEL NEUREITER, CHRISTINA WAGNER, MARIE-BERNADETTE ARETIN, STEFAN NEMEC, GABRIELE GAMERITH, GEORG PALL, RICHARD GREIL, THORSTEN FUEREDER
Publikováno v:
Anticancer Research. 43:1273-1282
Publikováno v:
memo - Magazine of European Medical Oncology. 15:201-205
SummaryThe biology of non-small cell lung cancer (NSCLC) is driven by a complex mutational landscape, and the detection of driver molecular alterations by next-generation sequencing is key for identification of druggable alterations. Thus, broad mole
Autor:
Gudrun Absenger, Michael Fiegl, Claudia Wild, Horst Olschewski, Robert Wurm, Florian Kocher, Florian Endel, Peter Heininger, Melanie Zechmeister, Sabine Geiger-Gritsch, André Hermann, Martin Flicker, Georg Pall
Publikováno v:
Wiener klinische Wochenschrift. 133:1122-1130
As real-world data regarding immunotherapy for non-small cell lung cancer are lacking for Austria, we conducted a retrospective study in six hospitals to present data from real-world practice. Patients with metastatic non-small cell lung cancer were
Autor:
Gabriele Gamerith, Marcel Kloppenburg, Finn Mildner, Arno Amann, Sabine Merkelbach-Bruse, Carina Heydt, Janna Siemanowski, Reinhard Buettner, Michael Fiegl, Claudia Manzl, Georg Pall
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5113
Effective targeted treatment strategies resulted from molecular profiling of lung cancer with distinct prevalent mutation profiles in smokers and non-smokers. Although Rn is the second most important risk factor, data for Rn-dependent driver events a
Autor:
Georg Pall, Gerlig Widmann, Dominik Wolf, Andreas Seeber, Andreas Pircher, Herbert Maier, Katja Schmitz, Laurenz Nagl
Publikováno v:
memo - Magazine of European Medical Oncology. 14:392-396
SummaryPrimary pulmonary sarcomas (PPS) are rare mesenchymal lung cancers, which do not present clinically or radiological different to lung carcinomas. Definite PPS diagnosis can only be made by histological analysis and detailed staging examination