Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Georg Nagel"'
Autor:
Sebastian Höler, Daniel Degreif, Florentine Stix, Shang Yang, Shiqiang Gao, Georg Nagel, Anna Moroni, Gerhard Thiel, Adam Bertl, Oliver Rauh
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280711 (2023)
Channelrhodopsin 2 (ChR2) and its variants are the most frequent tools for remote manipulation of electrical properties in cells via light. Ongoing attempts try to enlarge their functional spectrum with respect to ion selectivity, light sensitivity a
Externí odkaz:
https://doaj.org/article/01d20da6e6f643748470e4370eb4a6c6
Autor:
Shang Yang, Oana M. Constantin, Divya Sachidanandan, Hannes Hofmann, Tobias C. Kunz, Vera Kozjak-Pavlovic, Thomas G. Oertner, Georg Nagel, Robert J. Kittel, Christine E. Gee, Shiqiang Gao
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic cells. The soluble Beggiatoa photoactivatable adenylyl cyclase (bPAC) rapidly raises cAMP in
Externí odkaz:
https://doaj.org/article/57f6f60c5a00494697861315cebe0994
Autor:
Yujing Zhang, Pascal Benz, Daniel Stehle, Shang Yang, Hendrikje Kurz, Susanne Feil, Georg Nagel, Robert Feil, Shiqiang Gao, Markus Bender
Publikováno v:
Open Biology, Vol 12, Iss 8 (2022)
Cyclic guanosine monophosphate (cGMP) signalling plays a fundamental role in many cell types, including platelets. cGMP has been implicated in platelet formation, but mechanistic detail about its spatio-temporal regulation in megakaryocytes (MKs) is
Externí odkaz:
https://doaj.org/article/038d3a95dac349e997ed8766ea14c6f4
Autor:
Fei Chen, Xiaodong Duan, Yao Yu, Shang Yang, Yuanyuan Chen, Christine E. Gee, Georg Nagel, Kang Zhang, Shiqiang Gao, Yin Shen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/fcfeacb61b23499ebb7d29d8557d9ab7
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Background Microbial rhodopsins vary in their chemical properties, from light sensitive ion transport to different enzymatic activities. Recently, a novel family of two-component Cyclase (rhod)opsins (2c-Cyclop) from the green algae Chlamydo
Externí odkaz:
https://doaj.org/article/f4ef0243848b47cc971a96be64a25e57
Autor:
Jan Stephan Wichers, Paolo Mesén-Ramírez, Gwendolin Fuchs, Jing Yu-Strzelczyk, Jan Stäcker, Heidrun von Thien, Arne Alder, Isabelle Henshall, Benjamin Liffner, Georg Nagel, Christian Löw, Danny Wilson, Tobias Spielmann, Shiqiang Gao, Tim-Wolf Gilberger, Anna Bachmann, Jan Strauss
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Membrane transport proteins perform crucial roles in cell physiology. The obligate intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on membrane transport proteins for the uptake of nutrients from the host, disp
Externí odkaz:
https://doaj.org/article/a379ad10a39b42889f322ee25fa90b4b
Autor:
Chuanqiang Zhang, Shang Yang, Tom Flossmann, Shiqiang Gao, Otto W. Witte, Georg Nagel, Knut Holthoff, Knut Kirmse
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-17 (2019)
Abstract Background Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved
Externí odkaz:
https://doaj.org/article/dedf05e071574388863de33eb49f735b
Autor:
Sabine Panzer, Chong Zhang, Tilen Konte, Celine Bräuer, Anne Diemar, Parathy Yogendran, Jing Yu-Strzelczyk, Georg Nagel, Shiqiang Gao, Ulrich Terpitz
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Aureobasidium pullulans is a black fungus that can adapt to various stressful conditions like hypersaline, acidic, and alkaline environments. The genome of A. pullulans exhibits three genes coding for putative opsins ApOps1, ApOps2, and ApOps3. We he
Externí odkaz:
https://doaj.org/article/984d6d694b044e42a256c70c45498241
Publikováno v:
Membranes, Vol 12, Iss 10, p 907 (2022)
Voltage-gated sodium (Na+) channels respond to short membrane depolarization with conformational changes leading to pore opening, Na+ influx, and action potential (AP) upstroke. In the present study, we coupled channelrhodopsin-2 (ChR2), the key ion
Externí odkaz:
https://doaj.org/article/afb392a4d592462ebff4c9d735f81bcf
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background The green algae Chlamydomonas reinhardtii and Volvox carteri are important models for studying light perception and response, expressing many different photoreceptors. More than 10 opsins were reported in C. reinhardtii, yet only
Externí odkaz:
https://doaj.org/article/83d989b4439d4ddd884912026b34c0d7