Zobrazeno 1 - 10
of 675
pro vyhledávání: '"Georg N, Duda"'
Autor:
Tobias Winkler, Sven Geissler, Tazio Maleitzke, Carsten Perka, Georg N. Duda, Alexander Hildebrandt
Publikováno v:
EFORT Open Reviews, Vol 9, Iss 9, Pp 837-844 (2024)
Advanced therapies are expected to play a crucial role in supporting repair after injury, halting the degeneration of musculoskeletal tissue to enable and promote physical activity. Despite advancements, the progress in developing advanced therapies
Externí odkaz:
https://doaj.org/article/0534d29156c54a98bc14e8931ec34547
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Biophysical cues have the ability to enhance cellular signaling response to Bone Morphogenetic Proteins, an essential growth factor during bone development and regeneration. Yet, therapeutic application of Bone Morphogenetic Protein 2 (BMP2)
Externí odkaz:
https://doaj.org/article/ad074a2787c9465e8f9f6a4cd5f71794
Autor:
Jan Oliver Voss, Fabio Pivetta, Aboelyazid Elkilany, Katharina Schmidt-Bleek, Georg N. Duda, Kento Odaka, Ioanna Maria Dimitriou, Melanie Jasmin Ort, Mathias Streitz, Max Heiland, Steffen Koerdt, Simon Reinke, Sven Geissler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionOpen reduction and fixation are the standard of care for treating mandibular fractures and usually lead to successful healing. However, complications such as delayed healing, non-union, and infection can compromise patient outcomes and in
Externí odkaz:
https://doaj.org/article/f9204ac4f778463ba1ea93cd22bb8c3a
Autor:
Felix Eckstein, Thula Cannon Walter-Rittel, Akshay S. Chaudhari, Nicholas M. Brisson, Tazio Maleitzke, Georg N. Duda, Anna Wisser, Wolfgang Wirth, Tobias Winkler
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 3, Pp 100505- (2024)
Objective: This expert opinion paper proposes a design for a state-of-the-art magnetic resonance image (MRI) acquisition protocol for knee osteoarthritis clinical trials in early and advanced disease. Semi-quantitative and quantitative imaging endpoi
Externí odkaz:
https://doaj.org/article/c269e616f30f46968c643456f5bca826
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Tissue fibrosis is characterised by the high-energy consumption associated with myofibroblast contraction. Although myofibroblast contraction relies on ATP production, the role of cellular metabolism in myofibroblast contraction has not yet
Externí odkaz:
https://doaj.org/article/8bab7f35e5434a1ebd2b01cadc54e04e
Autor:
Hendrik Schmidt, Aboulfazl Shirazi-Adl, Maxim Bashkuev, Luis Alexander Becker, Matthias Pumberger, Georg N. Duda, Sandra Reitmaier
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Current clinical examination of low back pain (LBP) patients primarily relies on static clinical examinations, which rarely represent the dynamic postures patients adopt during daily activities. To gain an overview on the dynamic kinematics-kinetics
Externí odkaz:
https://doaj.org/article/35a92708101e4d44aed39eecc1ee37f0
Autor:
Charlotte Rinne, George A. Soultoukis, Masoome Oveisi, Marina Leer, Oskar Schmidt-Bleek, Lisa-Marie Burkhardt, Christian H. Bucher, Eman Abou Moussa, Melanie Makhlouf, Georg N. Duda, Luis R. Saraiva, Katharina Schmidt-Bleek, Tim J. Schulz
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionCaloric restriction (CR) is a nutritional intervention that increases life expectancy while lowering the risk for cardio-metabolic disease. Its effects on bone health, however, remain controversial. For instance, CR has been linked to inc
Externí odkaz:
https://doaj.org/article/a3fd60487d6e49f6b6c6c3d4557d4d33
Autor:
Alexander Hildebrandt, Tamara Dietrich, Jérôme Weber, Mara Meyer Günderoth, Sijia Zhou, Florian N. Fleckenstein, Shan Jiang, Tobias Winkler, Georg N. Duda, Serafeim Tsitsilonis, Johannes Keller, Tazio Maleitzke
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background The vasoactive neuropeptide calcitonin gene-related peptide alpha (αCGRP) enhances nociception in primary knee osteoarthritis (OA) and has been shown to disrupt cartilage and joint integrity in experimental rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/7fd8d19ce2db4dcf8b7b8bf3d7656959
Autor:
Julia Mehl, Saeed Khomeijani Farahani, Erik Brauer, Alexandra Klaus‐Bergmann, Tobias Thiele, Agnes Ellinghaus, Eireen Bartels‐Klein, Katharina Koch, Katharina Schmidt‐Bleek, Ansgar Petersen, Holger Gerhardt, Viola Vogel, Georg N. Duda
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Bone fracture healing is regulated by mechanobiological cues. Both, extracellular matrix (ECM) deposition and microvascular assembly determine the dynamics of the regenerative processes. Mechanical instability as by inter‐fragmentary shear
Externí odkaz:
https://doaj.org/article/2bcadc7c650844098b756206036103db
Autor:
Mariya M. Kucherenko, Pengchao Sang, Juquan Yao, Tara Gransar, Saphala Dhital, Jana Grune, Szandor Simmons, Laura Michalick, Dag Wulsten, Mario Thiele, Orr Shomroni, Felix Hennig, Ruhi Yeter, Natalia Solowjowa, Gabriela Salinas, Georg N. Duda, Volkmar Falk, Naren R. Vyavahare, Wolfgang M. Kuebler, Christoph Knosalla
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary artery may drive this pathology by increasing right ventricular dysfunction and lung vascular remodeling. Here we show increased stiffness of pulmonary
Externí odkaz:
https://doaj.org/article/748328d3565c40f5b56d90b3998604d9