Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Georg Michaelis"'
Autor:
Sefer Elezkurtaj, Selina Greuel, Jana Ihlow, Edward Georg Michaelis, Philip Bischoff, Catarina Alisa Kunze, Bruno Valentin Sinn, Manuela Gerhold, Kathrin Hauptmann, Barbara Ingold-Heppner, Florian Miller, Hermann Herbst, Victor Max Corman, Hubert Martin, Helena Radbruch, Frank L. Heppner, David Horst
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Infection by the new corona virus strain SARS-CoV-2 and its related syndrome COVID-19 has been associated with more than two million deaths worldwide. Patients of higher age and with preexisting chronic health conditions are at an increased
Externí odkaz:
https://doaj.org/article/87b08c6236304a3d8e02d2752ab143b8
Autor:
Markus Landthaler, Bernd Lamprecht, Riad Ghanem, Amjad Khan, Michael Mülleder, Maurice Reimann, Herta Steinkellner, Soyoung Lee, Emanuel Wyler, Mario Mairhofer, Wolfram Hoetzenecker, Paulina Richter-Pechanska, Séverine Kunz, Josef Tomasits, Rupert Langer, Kristina Dietert, Michael Schotsaert, Maria Pammer, Carles Martínez-Romero, Susanne Kimeswenger, Theresa C. Firsching, Jakob Trimpert, Melissa Uccellini, Achim D. Gruber, Bettina Purfürst, Adolfo García-Sastre, Clemens A. Schmitt, Reinhard Motz, Nikolaus Osterrieder, Anna Habringer, Markus Ralser, Julia Adler, Fahad Benthani, Martin Schönlein, Andrea Lau, Daniela Niemeyer, Christian Drosten, Dimitri Belenki, Dorothy N. Y. Fan, Roland Eils, Francesco Di Pierro, Lea Kausche, Gagandeep Singh, Christian Paar, Edward Georg Michaelis, Helmut J. F. Salzer, Yong Yu, Sabine Kaltenbrunner
Publikováno v:
Nature. 599(7884)
Derailed cytokine and immune cell networks account for the organ damage and the clinical severity of COVID-19 (refs. 1–4). Here we show that SARS-CoV-2, like other viruses, evokes cellular senescence as a primary stress response in infected cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c2767d2ebf83ab4c0372d59b825eab
https://pubmed.ncbi.nlm.nih.gov/34517409
https://pubmed.ncbi.nlm.nih.gov/34517409
Autor:
Jana Ihlow, Hermann Herbst, Selina Greuel, Helena Radbruch, Sefer Elezkurtaj, Jörg Westermann, Jenny Meinhardt, Verena Heynol, Victor M. Corman, Annika Lehmann, David Horst, Lars Bullinger, Edward Georg Michaelis, Ann-Christin von-Bruenneck, Florian Miller
Publikováno v:
Blood
Introduction: By now, the pandemic spread of COVID-19 (coronavirus disease 2019) has claimed more than 600,000 lives. The adaptive immune response seems to play a major role in the progression of the disease, since entry of SARS-CoV-2 (severe acute r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3a87b9fb5be1649b66647af44835ca
http://europepmc.org/articles/PMC8330254
http://europepmc.org/articles/PMC8330254
Publikováno v:
Molecular Genetics and Genomics. 271:616-626
The mitochondrial inner membrane peptidase IMP of Saccharomyces cerevisiae is required for proteolytic processing of certain mitochondrially and nucleus-encoded proteins during their export from the matrix into the inner membrane or the intermembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e3539c22dae499222b8491b9f0bcb0
https://doi.org/10.1007/s00438-004-1011-y
https://doi.org/10.1007/s00438-004-1011-y
Publikováno v:
Journal of Molecular Biology. 323:835-843
The yeast protein cytochrome c peroxidase (Ccp1) is nuclearly encoded and imported into the mitochondrial intermembrane space, where it is involved in degradation of reactive oxygen species. It is known, that Ccp1 is synthesised as a precursor with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833a30884a5ddcc2f56e71f2454b09b4
https://doi.org/10.1016/s0022-2836(02)01000-8
https://doi.org/10.1016/s0022-2836(02)01000-8
Publikováno v:
Scopus-Elsevier
In countries with a hot climate the mycotoxin citrinin represents a serious problem in fungal food-poisoning. In humans the renal system is affected the most and the mitochondrial respiratory chain was identified as a possible sensitive target for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25677788147ff2620f47b92aa3edf5a
https://doi.org/10.1007/s002940070001
https://doi.org/10.1007/s002940070001
Publikováno v:
Yeast. 15:921-933
In this study we report the construction and basic phenotypic analysis of six Saccharomyces cerevisiae deletion mutants. The open reading frames (ORFs) YJL008C (gene symbol CCT8), YJL010C, YJL011C, YJL012C, YJL017W, and YJL020C from chromosome X have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5876ea8cc63ee5f52b0d67c1d964aecb
https://doi.org/10.1002/(sici)1097-0061(199907)15:10b<921::aid-yea389>3.0.co
https://doi.org/10.1002/(sici)1097-0061(199907)15:10b<921::aid-yea389>3.0.co
Publikováno v:
Molecular and General Genetics MGG. 252:437-445
IMP1 encodes a subunit of the mitochondrial inner membrane peptidase responsible for the proteolytic processing of cytochrome oxidase subunit 2 (Cox2) and cytochrome b2 (Cytb2). The molecular defect in an imp1 mutation and the characterisation of a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f8c17d36a50a273d24eecea07d666f
https://doi.org/10.1007/bf02173009
https://doi.org/10.1007/bf02173009
Publikováno v:
Theoretical and Applied Genetics. :326-333
Simple sequence repeats (SSRs) are known to exhibit high degrees of variability even among closely related individuals. Their usage as nuclear genetic markers requires their conversion into sequence-tagged sites (STSs). In this paper we present the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6cedfea0a44043b47f093ee4b098c4
https://doi.org/10.1007/bf00223675
https://doi.org/10.1007/bf00223675
Publikováno v:
Yeast. 10:719-731
A yeast strain with a point mutation in the nuclear gene for the core subunit of mitochondrial RNA polymerase was used to isolate new extragenic suppressors. Spontaneously occurring phenotypical revertants were analysed by crosses with the wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092233cbb8fe998918e985c36a0f681b
https://doi.org/10.1002/yea.320100604
https://doi.org/10.1002/yea.320100604