Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Georg M. Singewald"'
Publikováno v:
Stress. 12:58-69
Chronic subordinate colony (CSC) housing has been recently validated as a murine model of chronic psychosocial stress which induces alterations of stress-related parameters including decreased body-weight gain and an increased level of anxiety in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e172bf07c5ab95cdbd8e72562fb727b1
https://doi.org/10.1080/10253890802042082
https://doi.org/10.1080/10253890802042082
Publikováno v:
Annals of the New York Academy of Sciences. 1144:61-73
In a previous work it was demonstrated that emotional stressors trigger the in vivo release of the neuropeptide substance P (SP) in brain areas known to be implicated in stress and anxiety mechanisms, such as the amygdala, lateral septum, nucleus acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dccafce269d507ea06c257650b1fcb6
https://doi.org/10.1196/annals.1418.018
https://doi.org/10.1196/annals.1418.018
Neurokinin 1 Receptor Antagonism Promotes Active Stress Coping Via Enhanced Septal 5-HT Transmission
Publikováno v:
BMC Pharmacology
Antagonists of the substance P (SP) preferring neurokinin 1 receptor (NK1R) represent a promising novel class of drugs for the treatment of stress-related disorders such as depression and anxiety disorders; however, the involved neuronal pathways rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b474a45d3b0f5f0be3dee96dacfa11
https://doi.org/10.1038/sj.npp.1301594
https://doi.org/10.1038/sj.npp.1301594
Publikováno v:
Neuropsychopharmacology
The lateral septum (LS) has been shown to have a key role in emotional processes and stress responses. However, the exact role of the LS on stress modulation is not clear, as previous lesion studies mostly used electrolytic lesions, thereby destroyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc2f5439dc8a3fa5e904b9766e193c4
https://pubmed.ncbi.nlm.nih.gov/21160468
https://pubmed.ncbi.nlm.nih.gov/21160468
Autor:
Mariana Spetea, Georg M. Singewald, Gary G. Chicchi, Kwei-Lan Tsao, Francesco Ferraguti, Nicolas Singewald, Helmut Schmidhammer, Karl Ebner, Hari Kishore Sreepathi, Clemens C. Thurner
Publikováno v:
Journal of neurochemistry. 106(6)
It has been shown that anxiety and stress responses are modulated by substance P (SP) released within the amygdala. However, there is an important gap in our knowledge concerning the mechanisms regulating extracellular SP in this brain region. To stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086bc22a688c03ce1375e677c07dc204
https://pubmed.ncbi.nlm.nih.gov/18673452
https://pubmed.ncbi.nlm.nih.gov/18673452
Autor:
Georg M. Singewald, Rachael L. Neve, Michel Barrot, Karl Ebner, Akshay Bhonsle, Vaishnav Krishnan, Herbert E. Covington, Tiffany L. Carle, Nicolas Singewald, Nadia M. Tsankova, Olivier Berton, Paula G. Ulery, Eric J. Nestler, Shari G. Birnbaum
Publikováno v:
Neuron
Neuron, Elsevier, 2007, 55 (2), pp.289-300. ⟨10.1016/j.neuron.2007.06.033⟩
Neuron, Elsevier, 2007, 55 (2), pp.289-300. ⟨10.1016/j.neuron.2007.06.033⟩
We analyzed the influence of the transcription factor DeltaFosB on learned helplessness, an animal model of affective disorder wherein a subset of mice exposed to inescapable stress (IS) develop a deficit in escape behavior. Repeated IS induces Delta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcc5ff1c53db71dffb32831fb96a068
https://doi.org/10.1016/j.neuron.2007.10.028
https://doi.org/10.1016/j.neuron.2007.10.028