Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Georg L, Wieser"'
Autor:
Alexander Pieper, Tilmann Götze, Ulli Bode, Sandra Goebbels, Georg L. Wieser, Jacques I. Wadiche, Kuo Yan, Hendrik Mießner, Ingo Bormuth, Markus H. Schwab, Bettina Duverge Castillo, Stephanie Rudolph, Tomoko Yonemasu, Iva D. Tzvetanova
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
The cerebellar cortex is involved in the control of diverse motor and non-motor functions. Its principal circuit elements are the Purkinje cells that integrate incoming excitatory and local inhibitory inputs and provide the sole output of the cerebel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e14f074070e19019509b9e2e5268a9
http://link.springer.com/article/10.1038/s41598-018-37850-7
http://link.springer.com/article/10.1038/s41598-018-37850-7
Autor:
Wiebke Möbius, Steffen Emmert, Mia Horowitz, Georg L. Wieser, Stina Schiller, Christina Seebode, Ofer Sarig, Sandra Goebbels, Eli Sprecher
Publikováno v:
The Journal of Investigative Dermatology : an International Journal for Research in Cutaneous Biology
Loss-of-function mutations in the synaptosomal-associated protein 29 ( SNAP29 ) gene cause the cerebral dysgenesis, neuropathy, ichthyosis, and keratoderma syndrome. In this study, we created total ( Snap29 –/– ) as well as keratinocyte-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ff4a0812f931109c52edf588d37867
Autor:
Georg L. Wieser, Steffen Emmert, Christina Seebode, Ofer Sarig, Torben Ruhwedel, Mia Horowitz, Sandra Goebbels, Debora Rapaport, Eli Sprecher, Stina Schiller
Publikováno v:
Experimental Dermatology. 25:647-649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8209ffd3c55afe526082ca2cccf955
https://doi.org/10.1111/exd.13050
https://doi.org/10.1111/exd.13050
Autor:
Bartosz Adamcio, Georg L. Wieser, Klaus-Armin Nave, Sandra Goebbels, Ulrike C. Gerwig, Hannelore Ehrenreich, Benoit Barrette
Publikováno v:
Glia. 61:869-880
Oligodendrocytes make myelin for rapid impulse propagation and contribute to the long-term survival of myelinated axons. The mechanisms by which oligodendroglial dysfunction(s) contribute to slowly progressive neurodegeneration are not well understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd4e980972990cba3adff4e2b9e904df
https://doi.org/10.1002/glia.22480
https://doi.org/10.1002/glia.22480
Autor:
Sven P. Wichert, Nicolas Renier, Julia M. Edgar, Marc Tessier-Lavigne, Klaus-Armin Nave, Georg L. Wieser, Khalad Karram, Bettina Weege, Moritz J. Rossner, Kuo Yan, Ragnhildur Thóra Káradóttir, Alexander Pieper, Amit Agarwal, Sandra Goebbels, Sonia Spitzer, Oleksandr Yagensky
The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1–mTOR pathway, we increased the caliber of normally unmyelinated axons and the expression of numerous genes encoding regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316358f58e5541deb8df73c79b0e8532
https://eprints.gla.ac.uk/130768/13/130768.pdf
https://eprints.gla.ac.uk/130768/13/130768.pdf
Autor:
Sandra, Goebbels, Georg L, Wieser, Alexander, Pieper, Sonia, Spitzer, Bettina, Weege, Kuo, Yan, Julia M, Edgar, Oleksandr, Yagensky, Sven P, Wichert, Amit, Agarwal, Khalad, Karram, Nicolas, Renier, Marc, Tessier-Lavigne, Moritz J, Rossner, Ragnhildur Thóra, Káradóttir, Klaus-Armin, Nave
Publikováno v:
Nature neuroscience. 20(1)
The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1-mTOR pathway, we increased the caliber of normally unmyelinated axons and the expression of numerous genes encoding regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::015682c499f1cc7de5955637fc6c4df2
https://pubmed.ncbi.nlm.nih.gov/27775720
https://pubmed.ncbi.nlm.nih.gov/27775720
Autor:
Georg L. Wieser, Hannelore Ehrenreich, Susann Boretius, Wiebke Möbius, Torben Ruhwedel, Giulia Poggi, Nicole Moschny, Imam Hassouna, Klaus-Armin Nave, Jürgen Baudewig, Hauke B. Werner, Sandra Goebbels
Publikováno v:
Glia
Subtle white matter abnormalities have emerged as a hallmark of brain alterations in magnetic resonance imaging or upon autopsy of mentally ill subjects. However, it is unknown whether such reduction of white matter and myelin contributes to any dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eba58daab026a74de76d38ba5f51220
http://resolver.sub.uni-goettingen.de/purl?gs-1/14054
http://resolver.sub.uni-goettingen.de/purl?gs-1/14054
Autor:
Nora, Hagemeyer, Sandra, Goebbels, Sergi, Papiol, Anne, Kästner, Sabine, Hofer, Martin, Begemann, Ulrike C, Gerwig, Susann, Boretius, Georg L, Wieser, Anja, Ronnenberg, Artem, Gurvich, Stephan H, Heckers, Jens, Frahm, Klaus-Armin, Nave, Hannelore, Ehrenreich
Publikováno v:
EMBO Molecular Medicine
Severe mental illnesses have been linked to white matter abnormalities, documented by postmortem studies. However, cause and effect have remained difficult to distinguish. CNP (2′,3′-cyclic nucleotide 3′-phosphodiesterase) is among the oligoden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3490afbdc39435c150b935efbf102aa8
https://pubmed.ncbi.nlm.nih.gov/22473874
https://pubmed.ncbi.nlm.nih.gov/22473874