Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Georg Kretzschmar"'
Autor:
María Victoria Zanardi, María Paula Gastiazoro, Georg Kretzschmar, Jannette Wober, Günter Vollmer, Jorgelina Varayoud, Milena Durando, Oliver Zierau
Publikováno v:
Molecular and cellular endocrinology. 543
Hops (Humulus lupulus) is used as an alternative to hormone replacement therapy due to the phytoestrogen, 8-prenylnaringenin (8-PN). To examine the potential risks/benefits of hops extract and its compounds (8-PN and 6-prenylnaringenin, 6-PN), we aim
Autor:
Dejan Nikolic, Tino Ehrhardt, Richard B. van Breemen, Georg Kretzschmar, Guido F. Pauli, Birgit M. Dietz, Annekathrin Martina Keiler, Manuela I. Bader, Oliver Zierau, Günter Vollmer, Janina Helle, Shao-Nong Chen, Judy L. Bolton, Ricardo Bernhardt, Kristin Nestler
Publikováno v:
Phytomedicine. 34:50-58
Background Hops ( Humulus lupulus (L.)) dietary supplements are of interest as herbal remedies to alleviate menopausal symptoms, such as hot flushes, depression and anxiety. So far, the evidence regarding estrogenic and related properties of hops pre
Autor:
Janina Helle, Annekathrin Martina Keiler, Leane Lehmann, Martin Tenniswood, Günter Vollmer, Sridar V. Chittur, Georg Kretzschmar, Peggy Dörfelt, JoEllen Welsh, Oliver Zierau
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 171:133-143
Polycyclic aromatic hydrocarbons (PAHs) are products of incomplete combustion of organic compounds, abundant in exhaust fumes and cigarette smoke. They act by binding to the aryl hydrocarbon receptor (AHR) which induces expression of phase 1 and phas
Autor:
Günter Vollmer, Janina Helle, Sridar V. Chittur, Georg Kretzschmar, Annekathrin Martina Keiler, Martin Tenniswood, Oliver Zierau, Manuela I. Bader
Publikováno v:
Environmental Health Perspectives
Background: Cross-talk between the aryl hydrocarbon receptor (AHR) and the estrogen receptor (ER) plays a major role in signaling processes in female reproductive organs. Objectives: We investigated the influence of the AHR ligand 3-methylcholanthren
Autor:
Sabina Schadyew, Georg Kretzschmar, Janina Helle, Martin Tenniswood, Sridar V. Chittur, Yanni Morgenroth, Oliver Zierau, Alexander Hennig, Martin Bentler
Publikováno v:
Journal of cellular biochemistry. 119(7)
The role of microRNAs (miRNA) in estrogen receptor (ER) signaling in the uterus and in endometrial cancer is not well understood. We therefore analyzed miRNA expression in uterine samples from a standard 3-day uterotrophic assay using young female ad
Autor:
George Lambrinidis, Günter Vollmer, Francesca Maria Raffaelli, Maria Halabalaki, Dieudonné Njamen, Josephine Hoepping, Emmanuel Mikros, Georg Kretzschmar, Sefirin Djiogue, Alexios-Leandros Skaltsounis
Publikováno v:
Planta Medica. 80:861-869
Erythrina poeppigiana is a medicinal plant which is widely used in Asia, Latin America, and Africa in traditional remedies for gynecological complications and maladies. In continuation of studies for the discovery of novel phytoestrogens, four erythr
Autor:
Manuela I. Bader, Janina Helle, Günter Vollmer, Kristin Kräker, Georg Kretzschmar, Annekathrin Martina Keiler, Oliver Zierau, JoEllen Welsh
Publikováno v:
Molecular and Cellular Endocrinology. 392:125-135
8-Prenylnaringenin (8-PN) and naringenin (Nar) are phytoestrogens found in food items and nutritional supplements, while 6-(1.1-dimethylallyl)naringenin (6-DMAN) is a component of an African plant. Besides their assumed beneficial effects they may pr
Publikováno v:
Journal of Cellular Physiology. 227:3434-3445
Due to the health risks attributed to perimenopausal hormone therapy, phytoestrogens such as flavonoids are receiving widespread attention to help alleviate menopausal symptoms, including hormone-driven mood disorders. Based on our previous reporter
Autor:
Felicitas Rataj, Georg Kretzschmar, Maria Jähne, Oliver Zierau, Patrick Diel, Günter Vollmer, Frank Möller
Publikováno v:
Archives of Toxicology. 86:1603-1612
The aryl hydrocarbon receptor (AHR) is known to mediate the cellular response to numerous xenobiotics including dioxin. Surprisingly AHR knockout mice provide evidence for the involvement of the AHR signalling cascade in estrogen regulated physiologi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 128:62-68
The efficacy of ERr 731(®), a commercially available extract isolated from Rheum rhaponticum, in terms of menopausal complaints like hot flushes, depression, anxiety and vaginal dryness has been proven in a two-year clinical study. Further a recent