Zobrazeno 1 - 10
of 429
pro vyhledávání: '"Georg GI"'
Autor:
Eya Khadhraoui, Leon Schmidt, Stefan Klebingat, Roland Schwab, Silvia Hernández-Durán, Georg Gihr, Harald Paukisch, Klaus-Peter Stein, Daniel Behme, Sebastian Johannes Müller
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background MR perfusion is a standard marker to distinguish progression and therapy-associated changes after surgery and radiochemotherapy for glioblastoma. TRAMs (Treatment Response Assessment Maps) were introduced, which are intended to fa
Externí odkaz:
https://doaj.org/article/bb95dce0863947a8899e1b3efc141072
Autor:
Tharusan Thevathasan, Sonia Lech, Andreas Diefenbach, Elisa Bechthold, Tim Gaßmann, Sebastian Fester, Georg Girke, Wulf Knie, Benjamin T. Lukusa, Sebastian Kühn, Steffen Desch, Ulf Landmesser, Carsten Skurk
Publikováno v:
Resuscitation Plus, Vol 20, Iss , Pp 100800- (2024)
Aim: Extracorporeal cardiopulmonary resuscitation (ECPR) by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) during refractory cardiac arrest presents significant medical and psychological challenges for healthcare providers. Beyond managi
Externí odkaz:
https://doaj.org/article/bc5de11bffaa4361ac147d6f068e68b2
Autor:
Vincent Rathkolb, Marianna T. Traugott, Andreas Heinzel, Marko Poglitsch, Judith Aberle, Farsad Eskandary, Agnes Abrahamowicz, Martin Mueller, Petra Knollmueller, Tarik Shoumariyeh, Jasmin Stuflesser, Ivan Seeber, Georg Gibas, Hannah Mayfurth, Viktoria Tinhof, Lukas Schmoelz, Markus Zeitlinger, Christian Schoergenhofer, Bernd Jilma, Bernd Genser, Wolfgang Hoepler, Sara Omid, Mario Karolyi, Christoph Wenisch, Rainer Oberbauer, Alexander Zoufaly, Manfred Hecking, Roman Reindl-Schwaighofer
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108146- (2023)
Summary: Despite the similar clinical outcomes after renin-angiotensin system (RAS) inhibitor (RASi) continuation or withdrawal in COVID-19, the effects on angiotensin-converting enzyme 2 (ACE2) and RAS metabolites remain unclear. In a substudy of th
Externí odkaz:
https://doaj.org/article/cde4c1a923a34b2a9fa80a213f0e9c8c
Autor:
Tharusan Thevathasan, Lisa Füreder, Dirk W. Donker, Christoph Nix, Thomas H. Wurster, Wulf Knie, Georg Girke, Abdulla S. Al Harbi, Ulf Landmesser, Carsten Skurk
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
IntroductionTo the best of our knowledge, this is the first case report which provides insights into patient-specific hemodynamics during veno-arterio-venous-extracorporeal membrane oxygenation (VAV ECMO) combined with a left-ventricular (LV) Impella
Externí odkaz:
https://doaj.org/article/c6777916ae344555bc5d13a0c1337baf
Autor:
Tamara Seitz, Johannes Holbik, Julian Hind, Georg Gibas, Mario Karolyi, Erich Pawelka, Marianna Traugott, Christoph Wenisch, Alexander Zoufaly
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT A high rate of bacterial and fungal superinfections was reported in critically ill patients with COVID-19. However, diagnosis can be challenging. The aim of this study is to evaluate the sensitivity and the clinical utility of the point-of-c
Externí odkaz:
https://doaj.org/article/b2b1a6edc66d455282df566c699f7305
Autor:
Tamara Seitz, Johannes Holbik, Alexander Grieb, Mario Karolyi, Julian Hind, Georg Gibas, Stephanie Neuhold, Alexander Zoufaly, Christoph Wenisch
Publikováno v:
Viruses, Vol 14, Iss 12, p 2785 (2022)
Background: The range of reported rates of bacterial and fungal superinfections in patients with a severe course of COVID-19 is wide, suggesting a lack of standardised reporting. Methods: The rates of bacterial and fungal superinfection were assessed
Externí odkaz:
https://doaj.org/article/9424292cb4204998bb2925467ca3b4a4
Publikováno v:
GEORG, GI, ALI, SM, BOGE, TC, DATTA, A, FALBORG, L, PARK, H, MEJILLANO, M & HIMES, RH 1995, ' SYNTHESIS OF BIOLOGICALLY-ACTIVE 2-BENZOYL PACLITAXEL ANALOGS ', Bioorganic & Medicinal Chemistry Letters, vol. 5, no. 3, pp. 259-264 .
The influence of aromatic substitution at the 2-benzoyl moiety of paclitaxel on biological activity was investigated, following the Topliss Operational Scheme. Twelve paclitaxel derivatives were synthesized and evaluated in a microtubule assembly ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::6989cf63f62ab0ecb1495ec838dc6dcf
https://pure.au.dk/portal/da/publications/synthesis-of-biologicallyactive-2benzoyl-paclitaxel-analogs(7fb059a9-208f-4aad-ae43-bffb3b59f040).html
https://pure.au.dk/portal/da/publications/synthesis-of-biologicallyactive-2benzoyl-paclitaxel-analogs(7fb059a9-208f-4aad-ae43-bffb3b59f040).html
Publikováno v:
GEORG, GI, ALI, SM, BOGE, TC, DATTA, A, FALBORG, L & HIMES, RH 1994, ' SELECTIVE C-2 AND C-4 DEACYLATION AND ACYLATION OF TAXOL-THE FIRST SYNTHESIS OF A C-4 SUBSTITUTED TAXOL ANALOG ', Tetrahedron Letters, vol. 35, no. 48, pp. 8931-8934 .
Hydrolytic procedures for selective 2-debenzoylation and 2,4-dideacylation of 2'-0-tert-butyldimethylsilyl-7-0-(triethylsilyl)taxol are reported. The first synthesis and biological evaluation of a 4-substituted analogue, 4-deacetyl-4-isobutanoyltaxol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::ee6bafeeb8af4c3f4586823ac30ffaa8
https://pure.au.dk/portal/da/publications/selective-c2-and-c4-deacylation-and-acylation-of-taxol--the-first-synthesis-of-a-c4-substituted-taxol-analog(c90d2280-41a8-429e-bdfb-681240b601a5).html
https://pure.au.dk/portal/da/publications/selective-c2-and-c4-deacylation-and-acylation-of-taxol--the-first-synthesis-of-a-c4-substituted-taxol-analog(c90d2280-41a8-429e-bdfb-681240b601a5).html
Publikováno v:
CHERUVALLATH, ZS, FALBORG, L, GEORG, GI, MITSCHER, LA, VANDERVELDE, D & YE, QM 1994, ' STUDIES DIRECTED TOWARDS THE SEMISYNTHESIS OF NOVEL TAXOIDS AND TAXOL ANALOGS ', pp. 100-MEDI .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::0c6ee1c0f42bbe6ab30a83818fbee896
https://pure.au.dk/portal/da/publications/studies-directed-towards-the-semisynthesis-of-novel-taxoids-and-taxol-analogs(8722c42b-eecc-43ac-889f-59844509c643).html
https://pure.au.dk/portal/da/publications/studies-directed-towards-the-semisynthesis-of-novel-taxoids-and-taxol-analogs(8722c42b-eecc-43ac-889f-59844509c643).html
Autor:
Georg Gihr, Diana Horvath-Rizea, Elena Hekeler, Oliver Ganslandt, Hans Henkes, Karl-Titus Hoffmann, Cordula Scherlach, Stefan Schob
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249878 (2021)
PurposeGlioblastoma and anaplastic astrocytoma represent the most commonly encountered high-grade-glioma (HGG) in adults. Although both neoplasms are very distinct entities in context of epidemiology, clinical course and prognosis, their appearance i
Externí odkaz:
https://doaj.org/article/34e2728db9464e63a0ffe1d7869c1edb