Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Georg F. Bischof"'
1
Akademický článek
Preclinical and clinical evaluation through serial colonoscopic evaluation of neratinib‐induced diarrhea in HER2‐positive breast cancer—A pilot study
Autor: Joanne Bowen, Sofia Braga, Valeria Dal Zotto, John Finnie, Daniel DiPrimeo, Blaire Cooke, Georg F. Bischof, Alvin Wong, Jack A. Di Palma
Publikováno v: Physiological Reports, Vol 12, Iss 16, Pp n/a-n/a (2024)
Abstract The irreversible pan‐HER tyrosine kinase inhibitor neratinib is approved for patients with HER2‐positive, early‐stage and metastatic breast cancer (BC). Neratinib‐associated diarrhea is the most common reason for early discontinuatio
Externí odkaz: https://doaj.org/article/4ac23f911fbd43ba915c155b47741514
Zobrazit plný text záznamu
2
Akademický článek
Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
Autor: Lucas Gonzalez-Nieto, Isabelle M Castro, Georg F Bischof, Young C Shin, Michael J Ricciardi, Varian K Bailey, Christine M Dang, Nuria Pedreño-Lopez, Diogo M Magnani, Keisuke Ejima, David B Allison, Hwi Min Gil, David T Evans, Eva G Rakasz, Jeffrey D Lifson, Ronald C Desrosiers, Mauricio A Martins
Publikováno v: PLoS Pathogens, Vol 15, Iss 9, p e1008015 (2019)
A prophylactic vaccine against human immunodeficiency virus (HIV) remains a top priority in biomedical research. Given the failure of conventional immunization protocols to confer robust protection against HIV, new and unconventional approaches may b
Externí odkaz: https://doaj.org/article/7e6e831fadc24404a14cf0b3646c06d4
Zobrazit plný text záznamu
3
Akademický článek
A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.
Autor: Young C Shin, Georg F Bischof, William A Lauer, Lucas Gonzalez-Nieto, Eva G Rakasz, Gregory M Hendricks, David I Watkins, Mauricio A Martins, Ronald C Desrosiers
Publikováno v: PLoS Pathogens, Vol 14, Iss 6, p e1007143 (2018)
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhe
Externí odkaz: https://doaj.org/article/46a4ad12534a4f0b9f9e81992fde32a8
Zobrazit plný text záznamu
4
Vaccine protection against SIVmac239 acquisition
Autor: Eva G. Rakasz, Mauricio A. Martins, Georg F. Bischof, Lucas Gonzalez-Nieto, Young C. Shin, Ronald C. Desrosiers, Jeffrey D. Lifson, David I. Watkins, William A. Lauer
Publikováno v: Proceedings of the National Academy of Sciences. 116:1739-1744
The biological characteristics of HIV pose serious difficulties for the success of a preventive vaccine. Molecularly cloned SIVmac239 is difficult for antibodies to neutralize, and a variety of vaccine approaches have had great difficulty achieving p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc69f0c19538f936f4cb7cf2765df09
https://doi.org/10.1073/pnas.1814584116
Zobrazit plný text záznamu
6
Use of a gamma-2 herpesvirus as a vector to deliver antibodies to rhesus monkeys
Autor: Sebastian P. Fuchs, Eva G. Rakasz, Young C. Shin, José M. Martinez-Navio, William A. Lauer, Georg F. Bischof, Ronald C. Desrosiers
Publikováno v: Gene Therapy. 24:487-492
The gamma-2 herpesvirus of rhesus monkeys, rhesus monkey rhadinovirus (RRV), persists principally in B cells of its host. We constructed recombinant strains of RRV expressing the rhesus monkey-derived anti-SIV monoclonal antibodies 4L6 and 5L7 and co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6168a7323786d9e39c8937bfa45b718
https://doi.org/10.1038/gt.2017.49
Zobrazit plný text záznamu
7
A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products
Autor: Mauricio A. Martins, Eva G. Rakasz, Georg F. Bischof, Lucas Gonzalez-Nieto, David I. Watkins, Young C. Shin, Gregory M. Hendricks, William A. Lauer, Ronald C. Desrosiers
Publikováno v: PLoS Pathogens, Vol 14, Iss 6, p e1007143 (2018)
PLoS Pathogens
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623c1f910d768de91cd60f7cd99c9953
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/10042
Zobrazit plný text záznamu
8
Use of a Recombinant Gamma-2 Herpesvirus Vaccine Vector against Dengue Virus in Rhesus Monkeys
Autor: Young C. Shin, Varian K. Bailey, Ronald C. Desrosiers, Diogo M. Magnani, Lucas Gonzalez-Nieto, Michael J. Ricciardi, Georg F. Bischof, David I. Watkins, Aline Domingues, Eva G. Rakasz
Research on vaccine approaches that can provide long-term protection against dengue virus infection is needed. Here we describe the construction, immunogenicity, and preliminary information on the protective capacity of recombinant, replication-compe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec9d17cab41d9fe369b90e0c2153c28
https://europepmc.org/articles/PMC5533908/
Zobrazit plný text záznamu
9
Importance of codon usage for the temporal regulation of viral gene expression
Autor: Ronald C. Desrosiers, Georg F. Bischof, William A. Lauer, Young C. Shin
The glycoproteins of herpesviruses and of HIV/SIV are made late in the replication cycle and are derived from transcripts that use an unusual codon usage that is quite different from that of the host cell. Here we show that the actions of natural tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052355935f24750c30ee3229322e6ef4
https://europepmc.org/articles/PMC4653223/
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje