Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Georg B T, Von Boyen"'
Autor:
Golsa Joodi, Jan Hendrik Niess, Karsten Mäder, Martin Neumann, Jens Walldorf, Marc Porzner, Julia Weissbach, Alexander Kleger, Thomas Seufferlein, Georg B T von Boyen
Publikováno v:
Inflammatory Bowel Diseases. 28:423-433
Background Neurotrophic growth factors can stabilize the intestinal barrier by preventing the apoptosis of enteric glial cells (EGCs) and enterocytes. We reasoned that a selective 5-HT1A receptor agonist may have neuroprotective properties in the gut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94d9339a3684bc9c745c6f9318cded7
https://doi.org/10.1093/ibd/izab191
https://doi.org/10.1093/ibd/izab191
Autor:
Stefan Schreiber, Georg B T von Boyen, Wolfgang Stremmel, Ion Dina, Juergen Stein, Gerhard Keilhauer, Peter Uebel, Andreas Kocjan, Limas Kupčinskas, Max Karner, Carsten Schmidt, Frank Zuelch
Publikováno v:
American Journal of Gastroenterology. 109:1041-1051
OBJECTIVES: Phosphatidylcholine is a key component of the mucosal barrier. Treatment with modified release phosphatidylcholine aims to improve the impaired barrier function. The primary objective is to evaluate the efficacy of LT-02, a newly designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03c675608e4e062e4d9442e363059d7
https://doi.org/10.1038/ajg.2014.104
https://doi.org/10.1038/ajg.2014.104
Autor:
M. Steinkamp, Carolin Pflüger, Ulrike Spaniol, Christoph Hartmann, Georg B T von Boyen, Nadine Schulte, Joachim Kirsch
Publikováno v:
Medical Science Monitor. 18:BR117-BR122
Background Enteric glia cells (EGCs) are essential for the integrity of the bowel. A loss of EGCs leads to a severe inflammation of the intestines. As a diminished EGC network is postulated in Crohn's disease (CD), we aimed to investigate if EGCs cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a44b7b5158ec3447965e8417ec279a9
https://doi.org/10.12659/msm.882612
https://doi.org/10.12659/msm.882612
Autor:
Benjamin Mayer, Ulrike Spaniol, Jochen Klaus, Georgia Lahr, Georg B T von Boyen, Johannes Stephani, Carolin Pflüger, Jan Hendrik Niess, N. Degenkolb
Publikováno v:
Digestive Diseases and Sciences
Background and Aims Great efforts have been made to predict disease behavior over time and the response to treatment in Crohn’s disease (CD). Such understanding could personalize therapy. Early introduction of more aggressive therapies to patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb4ed8f9335d9af1c1d3f97d088b0b1
http://europepmc.org/articles/PMC3306782
http://europepmc.org/articles/PMC3306782
Autor:
Georg B T von Boyen, M. Steinkamp
Publikováno v:
Neuron Glia Biology. 6:231-236
A neuro-glia interaction is part of gut inflammation and essential for the integrity of the bowel. A loss of enteric glia cells (EGCs) led to a fatal haemorrhagic jejuno-ileitis and death in a few days. Although a diminished EGC network is postulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53b2b1a96d46f519361097d848eb86b
https://doi.org/10.1017/s1740925x11000068
https://doi.org/10.1017/s1740925x11000068
Publikováno v:
Journal of Receptors and Signal Transduction. 26:329-336
Excitotoxicity, which is mediated via glutamate receptors, is also a phenomenon of the enteric nervous system. Whether enteric glial cells (EGCs), which resemble astrocytes of the central nervous system, express glutamate receptors and hence are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaaa5cbd66034c736aa5483464d967d
https://doi.org/10.1080/10799890600778821
https://doi.org/10.1080/10799890600778821
Autor:
Heike Gundel, Nadine Schulte, E Zizer, Carolin Pflueger, Georg B T von Boyen, Ulrike Spaniol, Martin Steinkamp
Publikováno v:
BMC Gastroenterology, Vol 12, Iss 1, p 6 (2012)
BMC Gastroenterology
BMC Gastroenterology
Background Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33f3d11ed10e678248eaa2fdd7f4f4e
http://www.biomedcentral.com/1471-230X/12/6
http://www.biomedcentral.com/1471-230X/12/6
Autor:
Jochen, Klaus, Max, Reinshagen, Katharina, Herdt, Guido, Adler, Georg B T, von Boyen, Christian, von Tirpitz
Publikováno v:
Journal of gastrointestinal and liver diseases : JGLD. 20(2)
Osteoporosis commonly afflicts Crohn's disease (CD) patients. Management remains unclear, with limited results for intravenous (i.v.) bisphosphonates and a follow-up longer than one year. Intravenous bisphosphonates bypass gastrointestinal-tract irri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83b3ea919b961cc5d43ae2be209cb639
https://pubmed.ncbi.nlm.nih.gov/21725510
https://pubmed.ncbi.nlm.nih.gov/21725510
Autor:
Max Reinshagen, Georg B T von Boyen, Christian von Tirpitz, Christoph Schröter, Jochen Klaus, Guido Adler, Katharina Herdt
AIM: To compare the effect of calcium and cholecalciferol alone and along with additional sodium fluoride or ibandronate on bone mineral density (BMD) and fractures in patients with Crohn’s disease (CD). METHODS: Patients (n =148) with reduced BMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598dceecd089771d206fbdffcc7214af
https://europepmc.org/articles/PMC3022293/
https://europepmc.org/articles/PMC3022293/
Autor:
Karl H Schäfer, Max Reinshagen, Martin Steinkamp, Irmlind Geerling, Joachim Kirsch, Georg B T von Boyen, Guido Adler
Publikováno v:
Inflammatory bowel diseases. 12(5)
Objectives: Imbalanced apoptosis of enterocytes is likely to be 1 of the mechanisms underlying Crohn's disease (CD). Apoptosis of enterocytes is regulated by glial-derived neurotrophic factor (GDNF), which is increased in CD. The cellular source of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3485313ddb5fe630e0341b02def352b
https://pubmed.ncbi.nlm.nih.gov/16670534
https://pubmed.ncbi.nlm.nih.gov/16670534