Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Georg B Keller"'
Autor:
Baba Yogesh, Georg B Keller
Publikováno v:
eLife, Vol 12 (2024)
Acetylcholine is released in visual cortex by axonal projections from the basal forebrain. The signals conveyed by these projections and their computational significance are still unclear. Using two-photon calcium imaging in behaving mice, we show th
Externí odkaz:
https://doaj.org/article/13766393047a48b58141efc80c4c47e7
Autor:
Matthias Heindorf, Georg B Keller
Publikováno v:
eLife, Vol 12 (2024)
Psychosis is characterized by a diminished ability of the brain to distinguish externally driven activity patterns from self-generated activity patterns. Antipsychotic drugs are a class of small molecules with relatively broad binding affinity for a
Externí odkaz:
https://doaj.org/article/1626927fcced42a294ef86e843c651f8
Autor:
Rebecca Jordan, Georg B Keller
Publikováno v:
eLife, Vol 12 (2023)
Prediction errors are differences between expected and actual sensory input and are thought to be key computational signals that drive learning related plasticity. One way that prediction errors could drive learning is by activating neuromodulatory s
Externí odkaz:
https://doaj.org/article/dbccf67bcfc24375bfca3b417f0a33f3
Publikováno v:
eLife, Vol 11 (2022)
Homeostatic regulation is essential for stable neuronal function. Several synaptic mechanisms of homeostatic plasticity have been described, but the functional properties of synapses involved in homeostasis are unknown. We used longitudinal two-photo
Externí odkaz:
https://doaj.org/article/1d5f71042f194154bd2a9221144e2f0f
Autor:
Chie Satou, Rachael L Neve, Hassana K Oyibo, Pawel Zmarz, Kuo-Hua Huang, Estelle Arn Bouldoires, Takuma Mori, Shin-ichi Higashijima, Georg B Keller, Rainer W Friedrich
Publikováno v:
eLife, Vol 11 (2022)
The zebrafish is an important model in systems neuroscience but viral tools to dissect the structure and function of neuronal circuitry are not established. We developed methods for efficient gene transfer and retrograde tracing in adult and larval z
Externí odkaz:
https://doaj.org/article/953084a35d814ae0a44b105f74d5fa17
Publikováno v:
eLife, Vol 11 (2022)
The experience of coupling between motor output and visual feedback is necessary for the development of visuomotor skills and shapes visuomotor integration in visual cortex. Whether these experience-dependent changes of responses in V1 depend on modi
Externí odkaz:
https://doaj.org/article/4ab9dec053444539934e4aa500424cc1
Autor:
Andreas J Keller, Rachael Houlton, Björn M Kampa, Nicholas A Lesica, Thomas D Mrsic-Flogel, Georg B Keller, Fritjof Helmchen
Publikováno v:
eLife, Vol 6 (2017)
A general principle of sensory processing is that neurons adapt to sustained stimuli by reducing their response over time. Most of our knowledge on adaptation in single cells is based on experiments in anesthetized animals. How responses adapt in awa
Externí odkaz:
https://doaj.org/article/0c9bc75227414097ae5398f5966251f2
Publikováno v:
PLoS Biology, Vol 14, Iss 10, p e2000317 (2016)
What cortical inputs are provided to motor control areas while they drive complex learned behaviors? We study this question in the nucleus interface of the nidopallium (NIf), which is required for normal birdsong production and provides the main sour
Externí odkaz:
https://doaj.org/article/7295c79744fb4652bbfd789f83ba7549
Publikováno v:
PLoS Biology, Vol 6, Iss 10, p e250 (2008)
To generate complex bilateral motor patterns such as those underlying birdsong, neural activity must be highly coordinated across the two cerebral hemispheres. However, it remains largely elusive how this coordination is achieved given that interhemi
Externí odkaz:
https://doaj.org/article/c7af61b33bb54a27ae6cc8072f3429e0