Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Georg B Keller"'
Autor:
Baba Yogesh, Georg B Keller
Publikováno v:
eLife, Vol 12 (2024)
Acetylcholine is released in visual cortex by axonal projections from the basal forebrain. The signals conveyed by these projections and their computational significance are still unclear. Using two-photon calcium imaging in behaving mice, we show th
Externí odkaz:
https://doaj.org/article/13766393047a48b58141efc80c4c47e7
Autor:
Sean M. O’Toole, Georg B. Keller
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103135- (2024)
Summary: Here, we present a sample collection protocol for single-cell RNA sequencing of functionally identified neuronal populations in vivo with a virally delivered activity-dependent labeling tool (CaMPARI2). We describe steps for photoconversion
Externí odkaz:
https://doaj.org/article/6bdca6b41d1949899300f73f513af6b3
Autor:
Matthias Heindorf, Georg B Keller
Publikováno v:
eLife, Vol 12 (2024)
Psychosis is characterized by a diminished ability of the brain to distinguish externally driven activity patterns from self-generated activity patterns. Antipsychotic drugs are a class of small molecules with relatively broad binding affinity for a
Externí odkaz:
https://doaj.org/article/1626927fcced42a294ef86e843c651f8
Autor:
Rebecca Jordan, Georg B Keller
Publikováno v:
eLife, Vol 12 (2023)
Prediction errors are differences between expected and actual sensory input and are thought to be key computational signals that drive learning related plasticity. One way that prediction errors could drive learning is by activating neuromodulatory s
Externí odkaz:
https://doaj.org/article/dbccf67bcfc24375bfca3b417f0a33f3
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112096- (2023)
Summary: The aim of this work is to provide a comment on a recent paper by Muzzu and Saleem (2021), which claims that visuomotor mismatch responses in mouse visual cortex can be explained by a locomotion-induced gain of visual halt responses. Our pri
Externí odkaz:
https://doaj.org/article/1cdf2bc600324b1d9cfeef1aa23d795a
Publikováno v:
eLife, Vol 11 (2022)
Homeostatic regulation is essential for stable neuronal function. Several synaptic mechanisms of homeostatic plasticity have been described, but the functional properties of synapses involved in homeostasis are unknown. We used longitudinal two-photo
Externí odkaz:
https://doaj.org/article/1d5f71042f194154bd2a9221144e2f0f
Autor:
Chie Satou, Rachael L Neve, Hassana K Oyibo, Pawel Zmarz, Kuo-Hua Huang, Estelle Arn Bouldoires, Takuma Mori, Shin-ichi Higashijima, Georg B Keller, Rainer W Friedrich
Publikováno v:
eLife, Vol 11 (2022)
The zebrafish is an important model in systems neuroscience but viral tools to dissect the structure and function of neuronal circuitry are not established. We developed methods for efficient gene transfer and retrograde tracing in adult and larval z
Externí odkaz:
https://doaj.org/article/953084a35d814ae0a44b105f74d5fa17
Publikováno v:
eLife, Vol 11 (2022)
The experience of coupling between motor output and visual feedback is necessary for the development of visuomotor skills and shapes visuomotor integration in visual cortex. Whether these experience-dependent changes of responses in V1 depend on modi
Externí odkaz:
https://doaj.org/article/4ab9dec053444539934e4aa500424cc1
Autor:
Aleena R. Garner, Georg B. Keller
Publikováno v:
Nature Neuroscience
Learned associations between stimuli in different sensory modalities can shape the way we perceive these stimuli. However, it is not well understood how these interactions are mediated or at what level of the processing hierarchy they occur. Here we