Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Georg A. Mathis"'
Autor:
Michael Lanz, Georg A. Mathis, W. A. Rambeck, Wolfgang Bittner, Susanne Kehrle, Heinrich Bachmann, Annick Toggenburger
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 173:301-307
Milk fever (MF) is a metabolic disease in dairy cows around parturition. The clinical lead sign is muscular paresis leading in severe cases to paralysis of the affected animal. Multiparturient animals of high performing dairy breeds are most likely t
Publikováno v:
Therapeutic innovationregulatory science. 52(3)
Although regulatory guidance defines which preclinical data are required in general before proceeding to first-in-human clinical trials, a certain level of flexibility exists in the actual planning, timing, and design of a drug development program. D
Autor:
Phoukham Phothirath, Heinrich Bachmann, Marie-Noëlle Horcajada, Peter Romeis, Elizabeth Offord-Cavin, Georg A. Mathis
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 136:333-336
Vitamin D requires two metabolic steps to become biologically active. In a first step 25-hydroxyvitamin D3 is formed, which acts as storage form. After a tightly controlled step in kidney the active metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) i
Publikováno v:
Schweizer Archiv fur Tierheilkunde. 158(12)
The safety of supplementing broiler feed with a standardised herbal extract, Solanum Glaucophyllum Standardised Leaves (SGSL) containing glycosylated 1a,25-dihydroxyvitamin D3 (1,25(OH)2D3) and standardised to contain 10 µg/g 1,25(OH)2D3 equivalent,
Autor:
Heinrich Bachmann, Georg A. Mathis, Annick Toggenburger, S. Autzen, R. Ibanez, P. Romeis, R. Pokorny
Publikováno v:
The Journal of steroid biochemistry and molecular biology.
A natural form of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D, was identified in glycosylated form in Solanum glaucophyllum (SG). Solbone P, an extract of SG with high and homogenous content of glycosylated 1,25(OH)2D3,
Autor:
Alphonse E. Sirica, Georg A. Mathis
Publikováno v:
In Vitro Cellular & Developmental Biology. 26:113-118
Select medium and substratum conditions were investigated for their effects on semiconservative DNA synthesis in essentially pure primary cultures of bile ductular epithelial cells that were initially isolated from cholestatic rat livers at 6 to 10 w
Publikováno v:
Pathobiology. 58:44-64
Recent advances made in the isolation, culture, and transplantation of defined populations of intrahepatic biliary epithelial cells and oval cells have permitted direct analysis of the functions, growth properties, and differentiation potential of th
Publikováno v:
Journal of cellular physiology. 146(2)
Freshly isolated hepatocytes from normal adult rat liver do not express measurable gamma-glutamyl transpeptidase (GGT) mRNA in contrast to the significant GGT mRNA levels expressed by normal adult rat kidney and hyperplastic bile ductular tissue from
Publikováno v:
Hepatology (Baltimore, Md.). 9(3)
An extensive bile ductular cell hyperplasia with the formation of well-differentiated bile ductules is the most prominent feature of rat liver at 6 to 15 weeks after bile duct ligation. We have improved our previous cell isolation procedure and are n