Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Georg, Pabst"'
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1300 (2023)
Membrane-active molecules provide a promising strategy to target and kill pathogenic bacteria. Understanding how specific molecular features drive interactions with membrane components and subsequently cause disruption that leads to antimicrobial act
Externí odkaz:
https://doaj.org/article/e95ef2fd6ba04913b133a601754e2ab4
Autor:
Enrico F Semeraro, Lisa Marx, Johannes Mandl, Ilse Letofsky-Papst, Claudia Mayrhofer, Moritz PK Frewein, Haden L Scott, Sylvain Prévost, Helmut Bergler, Karl Lohner, Georg Pabst
Publikováno v:
eLife, Vol 11 (2022)
We report the real-time response of Escherichia coli to lactoferricin-derived antimicrobial peptides (AMPs) on length scales bridging microscopic cell sizes to nanoscopic lipid packing using millisecond time-resolved synchrotron small-angle X-ray sca
Externí odkaz:
https://doaj.org/article/75cdca6652d94b5d8588a2a4cb453830
Autor:
Moritz P. K. Frewein, Milka Doktorova, Frederick A. Heberle, Haden L. Scott, Enrico F. Semeraro, Lionel Porcar, Georg Pabst
Publikováno v:
Symmetry, Vol 13, Iss 8, p 1441 (2021)
We addressed the frequent occurrence of mixed-chain lipids in biological membranes and their impact on membrane structure by studying several chain-asymmetric phosphatidylcholines and the highly asymmetric milk sphingomyelin. Specifically, we report
Externí odkaz:
https://doaj.org/article/cc35b9617efe4da59cb16fd73248a013
Autor:
Claudia Bernecker, Harald Köfeler, Georg Pabst, Martin Trötzmüller, Dagmar Kolb, Karl Strohmayer, Slave Trajanoski, Gerhard A. Holzapfel, Peter Schlenke, Isabel Dorn
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Ex vivo generation of red blood cells (cRBCs) is an attractive tool in basic research and for replacing blood components donated by volunteers. As a prerequisite for the survival of cRBCs during storage as well as in the circulation, the quality of t
Externí odkaz:
https://doaj.org/article/78cd14b974f747538647a84909a60d77
Publikováno v:
PNAS Nexus. 2
The activity of integral membrane proteins is tightly coupled to the properties of the surrounding lipid matrix. In particular, transbilayer asymmetry, a hallmark of all plasma membranes, might be exploited to control membrane-protein activity. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09eec3b8eff6f7bd03143247a7451630
https://doi.org/10.1093/pnasnexus/pgad126
https://doi.org/10.1093/pnasnexus/pgad126
Autor:
Ivo Kabelka, Vasil Georgiev, Lisa Marx, Peter Pajtinka, Karl Lohner, Georg Pabst, Rumiana Dimova, Robert Vácha
Publikováno v:
Biophysical Journal
We previously speculated that the synergistically enhanced antimicrobial activity of Magainin 2 and PGLa is related to membrane adhesion, fusion, and further membrane remodelling. Here, we combined computer simulations with time-resolved in vitro flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da66d7197a3b8938e09f95a67d68118
https://doi.org/10.1016/j.bpj.2021.12.035
https://doi.org/10.1016/j.bpj.2021.12.035
Publikováno v:
Membranes, Vol 5, Iss 2, Pp 180-196 (2015)
Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we
Externí odkaz:
https://doaj.org/article/f4f1b9c006c14fe08b86e4aaf58d7686
Autor:
James Jennings, Georg Pabst
Bicontinuous cubic phases offer advantageous routes to a broad range of applied materials ranging from drug delivery devices to membranes. However, a priori design of molecules that assemble into these phases remains a technological challenge. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003d1fce5747d088c509cbdb92922bda
https://doi.org/10.26434/chemrxiv-2022-q6pqt-v2
https://doi.org/10.26434/chemrxiv-2022-q6pqt-v2
Publikováno v:
Chemistry and Biochemistry Publications
Despite its discovery over 95 years ago, the biological and nutritional roles of vitamin E remain subjects of much controversy. Though it is known to possess antioxidant properties, recent assertions have implied that vitamin E may not be limited to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3812142fdb2b21251ebc89774d62917e
https://pubmed.ncbi.nlm.nih.gov/36027485
https://pubmed.ncbi.nlm.nih.gov/36027485
Publikováno v:
Biophysical Chemistry. 296:107002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c107f2a74d9a744f8531bd49e130c9
https://doi.org/10.1016/j.bpc.2023.107002
https://doi.org/10.1016/j.bpc.2023.107002