Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Georg, Feger"'
Publikováno v:
Expert Opinion on Drug Discovery. 2:621-631
Over the past 20 years, the biotechnology industry has been extraordinarily successful in bringing a wide variety of new products to the market, including recombinant versions of natural proteins such as growth hormone, insulin and the gonadotropins.
Autor:
Nathalie Picard-Riera, Lilia Bernasconi, Selvaraju Raghuram, Ursula Boschert, Rocco Cirillo, Christophe Losberger, Georg Feger, Virginia Avellana-Adalid, Ruben Papoian, Linda Kadi, Marie Kosco-Vilbois, Anne Baron-Van Evercooren, Pierre Graber
Publikováno v:
Molecular and Cellular Neuroscience. 25:707-721
We have used in vitro oligodendrocyte differentiation and the in vivo remyelination model, the cuprizone model, to identify genes regulating oligodendrocyte function and remyelination. One of the genes we identified, osteopontin (opn), is a secreted
Autor:
Birger Jansson, Enrico Domenici, Federico Faggioni, Niels Frandsen, Alessandro Gozzi, Donald M. Wallace, Alessandra Polissi, Massimo De Francesco, Georg Feger, Tracy C. Roberts, Rebecca Rimini
Publikováno v:
Molecular Microbiology. 36:1279-1292
The kinetics of global changes in transcription patterns during competence development in Streptococcus pneumoniae was analysed with high-density arrays. Four thousand three hundred and one clones of a S. pneumoniae library, covering almost the entir
Publikováno v:
Scopus-Elsevier
SUMMARY: The genes responsible for cell wall biosynthesis and cell division (dcw genes) were identified and sequenced in Streptococcus pneumoniae. The genetic organization of the dcw cluster in Streptococcus pneumoniae differed significantly from the
Autor:
Jacques Colinge, Georg Feger
Publikováno v:
Bioinformatics. 17:840-842
Summary: SAGE data are obtained by sequencing short DNA tags. Due to the mistakes in DNA sequencing, SAGE data contain errors. We propose a new approach to identify tags whose abundance is biased by sequencing errors. This approach is based on a conc
Publikováno v:
Cell Technology for Cell Products ISBN: 9781402054754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c98583c873149e4a62ff26c846aa6ebb
https://doi.org/10.1007/978-1-4020-5476-1_146
https://doi.org/10.1007/978-1-4020-5476-1_146
Autor:
Mckenna Sean D, Robert K. Campbell, Christie A. Kelton, Georg Feger, Rocco Cirillo, Pierre-Alain Vitte, Meijia Yang, Xuliang Jiang, Vittoria Ardissone
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 322(2)
A novel high-affinity inhibitor of tumor necrosis factor (TNF) is described, which is created by the fusion of the extracellular domains of TNF-binding protein 1 (TBP-1) to both the alpha and beta chains of an inactive version of the heterodimeric pr
Autor:
Georg Feger, Laurence Rey, Christian Arod, Jean-Philippe Gaudry, Thierry Battle, Bruno Antonsson, Holger Heine
Publikováno v:
ESACT Proceedings ISBN: 1402027915
This work describes the set-up and optimisation of a simple, robust and cost effective process for the high throughput production of recombinant proteins using HEK293EBNA cells at 100 ml scale. Several transfection reagents were tested and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6919113568b2089773dee1119325ba0
https://doi.org/10.1007/1-4020-3103-3_70
https://doi.org/10.1007/1-4020-3103-3_70
Autor:
Paola, Ghersa, Maurizio, Gelati, Jacques, Colinge, Georg, Feger, Christine, Power, Ruben, Papoian, Andrea, Salmaggi
Publikováno v:
Neuroreport. 13(1)
Different diseases of the CNS are associated with blood-brain barrier (BBB) damage and mononuclear cell infiltration. In order to study genes that may play a role in endothelial cell regulation in inflammatory CNS diseases, we performed differential
Autor:
Georg Feger
Publikováno v:
Gene. 227(2)
The minichromosome maintenance (MCM) gene family consists of six members (MCM2, 3, 4, 5, 6 and 7) in Saccharomyces cerevisiae as well as in humans. Each family member plays an essential role in the replication of DNA. In Drosophila melanogaster only