Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Geonir M, Siqueira"'
Autor:
Gabriele A. Berwaldt, Daniela P. Gouvêa, Daniel S. da Silva, Adriana M. das Neves, Mayara S. P. Soares, Juliana H. Azambuja, Geonir M. Siqueira, Roselia M. Spanevello, Wilson Cunico
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 196-202 (2019)
A series of nineteen benzothiazin-4-ones from N-(3-aminopropyl) piperidine, 4-(2-aminoethyl)morpholine or 1-(2-aminoethyl)piperidine, aliphatic or aromatic aldehyde and thiosalicylic acid, were synthesized in good yields by multicomponent one-pot rea
Externí odkaz:
https://doaj.org/article/54e36e7426904b669368aa53d875f9a9
Autor:
Auri R. Duval, Pedro H. Carvalho, Maieli C. Soares, Daniela P. Gouvêa, Geonir M. Siqueira, Rafael G. Lund, Wilson Cunico
Publikováno v:
The Scientific World Journal, Vol 11, Pp 1489-1495 (2011)
Fifteen 7-chloro-4-arylhydrazonequinolines have been evaluated for their in vitro antifungal activity against eight oral fungi: Candida albicans, C. parapsilosis, C. lipolytica, C. tropicalis, C. famata, C. glabrata, Rhodutorula mucilaginosa, and R.
Externí odkaz:
https://doaj.org/article/8afd6c2cb12a445b99ee5b089b2ebd1c
Autor:
Geonir M. Siqueira, Patrícia D. Neuenfeldt, Anaí Duarte, Lizandra C. Bretanha, Rogério A. Freitag, Wilson Cunico
Publikováno v:
Química Nova, Vol 33, Iss 3, Pp 707-715 (2010)
The synthesis and reactivity of α-oxoketenes dithioacetals (S,S-acetals), general structure [(R¹C=OC(R²)=C(SR³)(SR4)], are reported. We also showed the application of S,S acetals as synthons for efficient synthesis of isoxazoles, pyrazoles, indaz
Externí odkaz:
https://doaj.org/article/39cd2b36902143858ac3bcd331f67800
Autor:
Wilson Cunico, Daniela P. Gouvêa, Adriana M. das Neves, Geonir M. Siqueira, Mayara Sandrielly Pereira Soares, Gabriele A. Berwaldt, Juliana Hofstatter Azambuja, Daniel Schuch da Silva, Roselia Maria Spanevello
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 196-202 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
A series of nineteen benzothiazin-4-ones from N-(3-aminopropyl) piperidine, 4-(2-aminoethyl)morpholine or 1-(2-aminoethyl)piperidine, aliphatic or aromatic aldehyde and thiosalicylic acid, were synthesized in good yields by multicomponent one-pot rea
Autor:
Luiz Roberto Carraro Júnior, Cristiani F. Bortolatto, Amália Gonçalves Alves, Taís da Silva Teixeira Rech, Wilson Cunico, José Coan Campos Júnior, César Augusto Brüning, Geonir M. Siqueira
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 35
Some brain diseases are associated with oxidative stress and altered monoamine oxidase (MAO) activity. The objective of this study was to evaluate the antioxidant and neuroprotective actions through MAO inhibition of 3-(pyridin-2-yl)-2-(pyridine-2-yl
Autor:
Geonir M. Siqueira, Daniel Schuch da Silva, Adriana Lourenço da Silva, Giovana Duzzo Gamaro, Arthur H. S. Neves, Wilson Cunico
Publikováno v:
Medicinal Chemistry Research. 27:186-193
The present study assessed the 2,3-substituted-1,3-thiazolidin-4-ones antinociceptive potential looking at the acute nociception model induced by thermal stimulation in mice. This was done to contribute to the development of new analgesic drugs, in a
Autor:
Fabiane Knepper Zehetmeyr, Maria Antonieta Machado Pereira da Silva, Wilson Cunico, Silvia de Oliveira Hübner, José Coan Campos Júnior, Daniela P. Gouvêa, Maria Elisabeth Aires Berne, Geonir M. Siqueira, Patrícia da Silva Nascente, Karine Massia Pereira
Publikováno v:
Experimental parasitology. 192
Although there is a variety of biological activity reports regarding compounds derived from thiazolidin-4-ones, no data related to ovicidal activity against trematodes, particularly Fasciola hepatica are available. Since there are reports about anthe
Autor:
Beatriz Helena Gomes Rocha, Geonir M. Siqueira, Rosangela Ferreira Rodrigues, Paulo Romeu Gonçalves, Luciana Bicca Dode, Vera Lucia Bobrowski
Publikováno v:
Cadernos do Aplicação; v. 30, n. 1-2 (2017)
O “Pacto Nacional pelo Fortalecimento do Ensino Médio (PNEM) representa a articulação e coordenação de ações e estratégias entre a União e os governos estaduais na formulação e implementação de políticas para elevar o padrão de quali
Autor:
Hellen G. Masteloto, Geonir M. Siqueira, Patrícia D. Neuenfeldt, Wilson Cunico, Gabriele A. Berwaldt, Bruna B. Drawanz
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 146:327-334
New 2-aryl-3-(benzo[d][1,3]dioxol-5-yl)thiazolidin-4-ones were easily synthesized by one-pot reaction of (3,4-methylenedioxy)aniline, arenaldehydes (or cyclohexanone), and mercaptoacetic acid which results in good yields. The thiazolidinones were ful
Autor:
Francieli Moro Stefanello, Wilson Cunico, José C. Campos, Geonir M. Siqueira, Claudio M. P. Pereira, Daniela P. Gouvêa, Filipe S. P. Dutra, Camila da Silva Ribeiro
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 27:445-450
In the present study, we reported the efficient synthesis of 11 3-(pyrimidin-2-yl)-thiazolidinones in good yields using molecular sieve as the desiccant agent. In addition, we have evaluated the antioxidant capacity of the synthesized compounds by th