Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Geon Kwak"'
Autor:
Na-Young Park, Geon Kwak, Hyun-Myung Doo, Hye-Jin Kim, So-Young Jang, Yun-Il Lee, Byung-Ok Choi, Young-Bin Hong
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 2011-2021 (2021)
Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous disease affecting the peripheral nervous system that is caused by either the demyelination of Schwann cells or degeneration of the peripheral axon. Currently, there are no treatment opt
Externí odkaz:
https://doaj.org/article/0d05dcbda8e348daa3bf9ee143eff943
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 1, Pp 11-18 (2021)
Charcot-Marie-Tooth disease (CMT), a genetically heterogeneous group of diseases in the peripheral nervous system, is characterized by progressive and symmetrical distal weakness resulting in gait abnormality. The necessity of the diagnostic and prog
Externí odkaz:
https://doaj.org/article/fb34e66919fe417da246ec8bd9f871b9
Autor:
Geon Seong Lee, Geon Kwak, Ji Hyun Bae, Jeong Pil Han, Soo Hyun Nam, Jeong Hyeon Lee, Sumin Song, Gap-Don Kim, Tae Sub Park, Yang Kyu Choi, Byung-Ok Choi, Su Cheong Yeom
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
The microrchidia (MORC)-family CW-type zinc finger 2 (MORC2) gene is related to DNA repair, adipogenesis and epigenetic silencing via the human silencing hub (HUSH) complex. MORC2 missense mutation is known to cause peripheral neuropathy of Charcot-M
Externí odkaz:
https://doaj.org/article/ff35c3cd53c74585a5924306be1525fd
Autor:
Ji-Su Lee, Eun Hyuk Chang, Ok Jae Koo, Dong Hwan Jwa, Won Min Mo, Geon Kwak, Hyo Won Moon, Hwan Tae Park, Young Bin Hong, Byung-Ok Choi
Publikováno v:
Neurobiology of Disease, Vol 100, Iss , Pp 99-107 (2017)
Charcot-Marie-Tooth disease (CMT) is a genetic disorder that can be caused by aberrations in >80 genes. CMT has heterogeneous modes of inheritance, including autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive. Over 95%
Externí odkaz:
https://doaj.org/article/046a240c8f184ec19b972d729e7d7f0b
Autor:
Young Bin Hong, Jaesoon Joo, Young Se Hyun, Geon Kwak, Yu-Ri Choi, Ha Kyung Yeo, Dong Hwan Jwa, Eun Ja Kim, Won Min Mo, Soo Hyun Nam, Sung Min Kim, Jeong Hyun Yoo, Heasoo Koo, Hwan Tae Park, Ki Wha Chung, Byung-Ok Choi
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005829 (2016)
Charcot-Marie-Tooth disease (CMT) is a heterogeneous group of peripheral neuropathies with diverse genetic causes. In this study, we identified p.I43N mutation in PMP2 from a family exhibiting autosomal dominant demyelinating CMT neuropathy by whole
Externí odkaz:
https://doaj.org/article/7d3a1c012e2d4792841fc3db70e1d610
Autor:
Namhee Jung, Saeyoung Park, Yoonyoung Choi, Joo-Won Park, Young Bin Hong, Hyun Ho Choi Park, Yeonsil Yu, Geon Kwak, Han Su Kim, Kyung-Ha Ryu, Jae Kwang Kim, Inho Jo, Byung-Ok Choi, Sung-Chul Jung
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 11, p 1867 (2016)
Schwann cells (SCs), which produce neurotropic factors and adhesive molecules, have been reported previously to contribute to structural support and guidance during axonal regeneration; therefore, they are potentially a crucial target in the restorat
Externí odkaz:
https://doaj.org/article/e3ac2d3cc24248a88ac3b7aefad4fe46
Autor:
Hyeonjin Jeon, So Young Jang, Geon Kwak, Yong Weon Yi, Mi-Hyeon You, Na Young Park, Ju Hee Jo, Ji Won Yang, Hye Ji Jang, Sun-Young Jeong, Seung Kee Moon, Hyun Myung Doo, Minyeop Nahm, Donghoon Kim, Jong Wook Chang, Byung-Ok Choi, Young Bin Hong
Publikováno v:
Brain.
The duplication of the peripheral myelin protein 22 (PMP22) gene causes a demyelinating type of neuropathy, commonly known as Charcot–Marie–Tooth disease type 1A (CMT1A). Development of effective drugs for CMT1A still remains as an unmet medical
Autor:
Hyeonjin Jeon, Hye Jin Kim, Hyun Myung Doo, Eun Hyuk Chang, Geon Kwak, Won Min Mo, So Young Jang, Myoung Woo Lee, Byung-Ok Choi, Young Bin Hong
Publikováno v:
Biochemical and Biophysical Research Communications. 597:1-7
Demyelinating Charcot-Marie-Tooth disease (CMT) is caused by mutations in the genes that encode myelinating proteins or their transcription factors. Our study thus sought to assess the therapeutic effects of cytokines secreted from mesenchymal stem c
Autor:
Hye Jin Kim, Yun-Il Lee, Hyun-Myung Doo, Geon Kwak, Young-Bin Hong, Na-Young Park, So-Young Jang, Byung-Ok Choi
Publikováno v:
Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 138-2021
Current Issues in Molecular Biology, Vol 43, Iss 138, Pp 2011-2021 (2021)
Volume 43
Issue 3
Pages 138-2021
Current Issues in Molecular Biology, Vol 43, Iss 138, Pp 2011-2021 (2021)
Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous disease affecting the peripheral nervous system that is caused by either the demyelination of Schwann cells or degeneration of the peripheral axon. Currently, there are no treatment opt
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 1, Pp 11-18 (2021)
Animal Cells and Systems
article-version (VoR) Version of Record
Animal Cells and Systems
article-version (VoR) Version of Record
Charcot-Marie-Tooth disease (CMT), a genetically heterogeneous group of diseases in the peripheral nervous system, is characterized by progressive and symmetrical distal weakness resulting in gait abnormality. The necessity of the diagnostic and prog