Výsledky vyhledávání - "Geoffry Knudsen"

FoxP3 Enhances HIV-1 Gene Expression by Modulating NFκB Occupancy at the Long Terminal Repeat in Human T Cells

Autor: Derek A. Holmes, Lishan Su, Stephanie L. Mackey-Cushman, Geoffry Knudsen

Publikováno v: Journal of Biological Chemistry. 282:15973-15980

FoxP3 determines the development of CD4+CD25+ regulatory T (Treg) cells and represses interleukin-2 (IL-2) expression in Treg cells. However, human immunodeficiency virus type 1 (HIV-1) infects and replicates efficiently in FoxP3+ Treg cells. We repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deef5a3e3d3d8cbece5e7bbf4e9d7b6
https://doi.org/10.1074/jbc.m702051200

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Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP

Autor: Geoffry Knudsen, Qi Jiang, Hua Su, Lishan Su, Whitney S. Helms

Publikováno v: BMC Immunology, Vol 7, Iss 1, p 6 (2006)
BMC Immunology

BackgroundGeneration of functional CD4+CD8-CD25+regulatory T cells (Treg) in the murine thymus depends on FoxP3. Removal of the thymus from neonatal mice has been shown to result in a multiple organ autoimmune disease phenotype that can be prevented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7995164a2c4a2da5d8a3736f36caaa6e
http://www.biomedcentral.com/1471-2172/7/6

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