Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Geoffroy Sorin"'
Publikováno v:
Organic Letters. 24:5721-5725
Herein, we develop a novel and straightforward access to cyclic conjugated enynes catalyzed by silver carbonate/DBU from readily available substrates with good yields. The reaction is easy to set up, broad in scope, and can also be conducted in a one
Autor:
Marie-Isabelle Lannou, Janick Ardisson, Geoffroy Sorin, Luca Allievi, Rongyu Sun, Mohamed Selkti, Sabrina Dhambri
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2021, 23 (13), pp.5218-5222. ⟨10.1021/acs.orglett.1c01757⟩
Organic Letters, American Chemical Society, 2021, 23 (13), pp.5218-5222. ⟨10.1021/acs.orglett.1c01757⟩
International audience; Vibsatin A is a new neurotrophic vibsane-type diterpenoid comprising a bridged bicyclo[4.2.1]nonane skeleton. Inspired by Sawamura’s works, we generated the bicyclic backbone through a Conia-ene-derived 7-exo-dig cyclization
Publikováno v:
Chemical communications (Cambridge, England). 58(9)
A novel access to fused furan cores using silver oxide(I) has been developed. Mechanistic investigations indicate the involvement of a Conia-ene reaction/radical cyclization for an expedient path to complex furan derivatives. The reaction is broad in
Autor:
Janick Ardisson, Florent Bodinier, Geoffroy Sorin, Patrice Gerardo, Maximiliene Saague-Tenefo, Bao Yu, Marie-Isabelle Lannou
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2021, 2021 (25), pp.3634-3640. ⟨10.1002/ejoc.202100418⟩
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2021, 2021 (25), pp.3634-3640. ⟨10.1002/ejoc.202100418⟩
International audience; We describe herein the one-pot synthesis of α-amino nitrile units by the concomitant addition of alkyl (or aryl) Grignard reagents and TMS cyanide through alkylative Strecker cyanation from readily available formamides. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038ef9266f26d4986639a8d27161874b
https://hal.archives-ouvertes.fr/hal-03366205
https://hal.archives-ouvertes.fr/hal-03366205
Autor:
Luca, Allievi, Sabrina, Dhambri, Rongyu, Sun, Mohamed, Selkti, Marie-Isabelle, Lannou, Geoffroy, Sorin, Janick, Ardisson
Publikováno v:
Organic letters. 23(13)
Vibsatin A is a new neurotrophic vibsane-type diterpenoid comprising a bridged bicyclo[4.2.1]nonane skeleton. Inspired by Sawamura's works, we generated the bicyclic backbone through a Conia-ene-derived 7
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2021, 57 (29), pp.3603-3606. ⟨10.1039/d1cc00081k⟩
Chemical Communications, Royal Society of Chemistry, 2021, 57 (29), pp.3603-3606. ⟨10.1039/d1cc00081k⟩
International audience; Herein, we describe unprecedented access to all-carbon or heterocyclic seven-membered ring frameworks from 1,8-ene-ynes promoted by inexpensive low-valent titanium(II) species, readily available from Ti(OiPr)4 and Grignard rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f97ece7ddc58346d37f26be5ba89ca9
https://hal.archives-ouvertes.fr/hal-03366094
https://hal.archives-ouvertes.fr/hal-03366094
Autor:
Sabrina Dhambri, Ilaria Ciofini, Marie-Isabelle Lannou, Anna Perfetto, Bao Yu, Marie-Noëlle Rager, Geoffroy Sorin, Mohamed Selkti, Luca Allievi
Publikováno v:
Chemistry – A European Journal
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202002696⟩
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202002696⟩
A formal [3+2] cyclization mediated by silver(I) oxide and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) is described herein. Through a broad variety of carbonyl compounds, this system can promote cyclization reactions with high yield (up to 85 %) and dia
Autor:
François Sautel, Sabrina Dhambri, Guillaume Boissonnat, Camille Lecourt, Georges Massiot, Geoffroy Sorin, Srikanth Boinapally, Janine Cossy, Christophe Meyer, Janick Ardisson, Marie-Isabelle Lannou
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2016, 81 (24), pp.12275-12290. ⟨10.1021/acs.joc.6b02208⟩
Journal of Organic Chemistry, American Chemical Society, 2016, 81 (24), pp.12275-12290. ⟨10.1021/acs.joc.6b02208⟩
International audience; The synthesis of the C1–C27 fragment of hemicalide, a marine metabolite displaying a unique potent antiproliferative activity, has been accomplished. The synthetic approach highlights a remarkably efficient ring-closing meta
Autor:
Alan Jeuken, Geoffroy Sorin, Mohamed Selkti, Youssouf Sanogo, Janick Ardisson, Raja Ben Othman, Sabrina Dhambri, Joëlle Prunet, Jean-Pierre Férézou, Marie-Isabelle Lannou
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2019, 84 (9), pp.5821-5830. ⟨10.1021/acs.joc.8b03249⟩
Journal of Organic Chemistry, American Chemical Society, 2019, 84 (9), pp.5821-5830. ⟨10.1021/acs.joc.8b03249⟩
A novel approach toward the [5—7]fused bicyclic core of thapsigargin, a subnanomolar inhibitor of the endo/sarcoplasmic calcium ATPase (SERCA), is presented. The synthetic route includes an original Ti(II)-mediated hydroxy-directed reductive coupli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df22f3cd47dc7dcaa5efcf6848763b3
https://hal.archives-ouvertes.fr/hal-02370403/document
https://hal.archives-ouvertes.fr/hal-02370403/document
Autor:
Simon Specklin, Camille Lecourt, Georges Massiot, Janine Cossy, Geoffroy Sorin, Christophe Meyer, Eric Auclair, Etienne Fleury, Antonio Grondin, Khalil Yamani, Karim Hammad, François Sautel, Paola B. Arimondo, Janick Ardisson, Marie-Isabelle Lannou, Sabrina Dhambri, Serge Sablé, Guillaume Boissonnat
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2019, 25 (11), pp.2745-2749. ⟨10.1002/chem.201806327⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2019, 25 (11), pp.2745-2749. ⟨10.1002/chem.201806327⟩
International audience; A strategy for the assembly of the entire carbon backbone of a stereoisomer of the antitumor marine natural product hemicalide has been investigated. The devised convergent approach relies on Horner–Wadsworth–Emmons and Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7df7729a2c0fd815fe46c6aed4a8730
https://hal.archives-ouvertes.fr/hal-02379818
https://hal.archives-ouvertes.fr/hal-02379818