Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Geoffroy, Laumet"'
Publikováno v:
Neurobiology of Pain, Vol 15, Iss , Pp 100149- (2024)
Chronic pain treatment remains a major challenge and pharmacological interventions are associated with important side effects. Manual medicine treatments such as massage, acupuncture, manipulation of the fascial system (MFS), and osteopathic manipula
Externí odkaz:
https://doaj.org/article/04f9cbad44cc49a4a92d08d0d87e18dd
Autor:
Edmone Dewaeles, Kévin Carvalho, Sandy Fellah, Jaewon Sim, Nihad Boukrout, Raphaelle Caillierez, Hariharan Ramakrishnan, Cynthia Van der Hauwaert, Jhenkruthi Vijaya Shankara, Nathalie Martin, Noura Massri, Agathe Launay, Joseph K. Folger, Clémentine de Schutter, Romain Larrue, Ingrid Loison, Marine Goujon, Matthieu Jung, Stéphanie Le Gras, Victoria Gomez-Murcia, Emilie Faivre, Julie Lemaire, Anne Garat, Nicolas Beauval, Patrice Maboudou, Viviane Gnemmi, Jean-Baptiste Gibier, Luc Buée, Corinne Abbadie, Francois Glowacki, Nicolas Pottier, Michael Perrais, Rodrigo A. Cunha, Jean-Sébastien Annicotte, Geoffroy Laumet, David Blum, Christelle Cauffiez
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Cisplatin is a potent chemotherapeutic drug that is widely used in the treatment of various solid cancers. However, its clinical effectiveness is strongly limited by frequent severe adverse effects, in particular nephrotoxicity and chemotherapy-induc
Externí odkaz:
https://doaj.org/article/f322febb20a9426fac11bb1c684e29af
Autor:
Dionna W. Williams, Bianca R. Flores, Yanxun Xu, Yuezhe Wang, Danyang Yu, Brandilyn A. Peters, Adebola Adedimeji, Tracey E. Wilson, Daniel Merenstein, Phyllis C. Tien, Mardge H. Cohen, Kathleen M. Weber, Adaora A. Adimora, Igho Ofotokun, Margaret Fischl, Janet Turan, Bülent Turan, Geoffroy Laumet, Alan L. Landay, Raha M. Dastgheyb, Stephen J. Gange, Sheri D. Weiser, Leah H. Rubin
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 25, Iss , Pp 100498- (2022)
Neuropsychiatric complications are common among women with HIV (WWH). The pathophysiological mechanisms underlying these complications are not fully known but likely driven in part by immune modulation. We examined associations between T-cell activat
Externí odkaz:
https://doaj.org/article/343c52777eb14015a1b0466b4d2aeebd
Publikováno v:
Neurobiology of Pain, Vol 7, Iss , Pp - (2020)
Background: Chronic pain and depression often co-occur. The mechanisms underlying this comorbidity are incompletely understood. Here, we investigated the role of CD3+ T cells in an inflammatory model of comorbid persistent mechanical allodynia, spont
Externí odkaz:
https://doaj.org/article/c2df184179964210be6fc7fa423eab40
Autor:
Geoffroy Laumet, Jiacheng Ma, Alfred J. Robison, Susmita Kumari, Cobi J. Heijnen, Annemieke Kavelaars
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The immune system is critically involved in the development and maintenance of chronic pain. However, T cells, one of the main regulators of the immune response, have only recently become a focus of investigations on chronic pain pathophysiology. Eme
Externí odkaz:
https://doaj.org/article/bbad8f1532254bdbb5ef621eede3c232
Autor:
Rabail Khan, Beenhwa Grace Lee, Kufreobong Inyang, Raluca Bugescu, Erica Tanushi, Koralee Santiago, Geoffroy Laumet, Gina Leinninger
Publikováno v:
Physiology. 38
The plague of chronic pain has fueled the U.S. opioid epidemic, creating a critical need for novel pain therapeutics that do not cause dependence. In preclinical models, central treatment with the neuropeptide Neurotensin (Nts) or Nts receptor agonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50390298933f7445adf981b20b10d380
https://doi.org/10.1152/physiol.2023.38.s1.5727588
https://doi.org/10.1152/physiol.2023.38.s1.5727588
Autor:
Florent Letronne, Geoffroy Laumet, Anne-Marie Ayral, Julien Chapuis, Florie Demiautte, Mathias Laga, Michel E. Vandenberghe, Nicolas Malmanche, Florence Leroux, Fanny Eysert, Yoann Sottejeau, Linda Chami, Amandine Flaig, Charlotte Bauer, Pierre Dourlen, Marie Lesaffre, Charlotte Delay, Ludovic Huot, Julie Dumont, Elisabeth Werkmeister, Franck Lafont, Tiago Mendes, Franck Hansmannel, Bart Dermaut, Benoit Deprez, Anne-Sophie Hérard, Marc Dhenain, Nicolas Souedet, Florence Pasquier, David Tulasne, Claudine Berr, Jean-Jacques Hauw, Yves Lemoine, Philippe Amouyel, David Mann, Rebecca Déprez, Frédéric Checler, David Hot, Thierry Delzescaux, Kris Gevaert, Jean-Charles Lambert
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 278-292 (2016)
Although several ADAMs (A disintegrin-like and metalloproteases) have been shown to contribute to the amyloid precursor protein (APP) metabolism, the full spectrum of metalloproteases involved in this metabolism remains to be established. Transcripto
Externí odkaz:
https://doaj.org/article/b6a220c6a95c4d56a4492c3f25a412a8
Autor:
Amna Khan, Adnan Khan, Sidra Khalid, Bushra Shal, Eunwoo Kang, Hwaryeong Lee, Geoffroy Laumet, Eun Kyoung Seo, Salman Khan
Publikováno v:
Molecules, Vol 26, Iss 1, p 181 (2021)
7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid obtained from a natural source has proved to be effective in minimizing various side effects associated with opioids and nonsteroidal anti
Externí odkaz:
https://doaj.org/article/03fbcc4228824fccb50bbf20411f4e91
Autor:
Aurore Latragna, Alba Sabaté San José, Panagiotis Tsimpos, Simon Vermeiren, Roberta Gualdani, Sampurna Chakrabarti, Gerard Callejo, Simon Desiderio, Orr Shomroni, Maren Sitte, Sadia Kricha, Maëlle Luypaert, Benoit Vanhollebeke, Geoffroy Laumet, Gabriela Salinas, Ewan St. John Smith, Laurence Ris, Eric J. Bellefroid
Publikováno v:
Pain. 163:e927-e941
Prdm12 is a conserved epigenetic transcriptional regulator that displays restricted expression in nociceptors of the developing peripheral nervous system. In mice, Prdm12 is required for the development of the entire nociceptive lineage. In humans, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1af7e5693bca48133bc8da17f4b5cf
https://doi.org/10.1097/j.pain.0000000000002536
https://doi.org/10.1097/j.pain.0000000000002536
Autor:
Christian S. Stohler, Phillip L. Campbell, Robert Dantzer, Alan R. Prossin, Jon Kar Zubieta, Alisa E. Koch, Geoffroy Laumet
Publikováno v:
Molecular Psychiatry. 27:831-839
Behavioral conditioning and expectation can have profound impact on animal and human physiology. Placebo, administered under positive expectation in clinical trials, can have potent effects on disease pathology, obscuring active medications. Emerging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbfc8bc739bb1e45b140b0dfce20640
https://doi.org/10.1038/s41380-021-01365-x
https://doi.org/10.1038/s41380-021-01365-x