Výsledky vyhledávání - "Geoffrey van der Plasse"

Akademický článek

A neuronal mechanism underlying decision-making deficits during hyperdopaminergic states

Autor: Jeroen P. H. Verharen, Johannes W. de Jong, Theresia J. M. Roelofs, Christiaan F. M. Huffels, Ruud van Zessen, Mieneke C. M. Luijendijk, Ralph Hamelink, Ingo Willuhn, Hanneke E. M. den Ouden, Geoffrey van der Plasse, Roger A. H. Adan, Louk J. M. J. Vanderschuren

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Aberrant increased dopaminergic function results in impaired value-based decision making. Here the authors report pathway-specific effects of VTA activation on distinct aspects of flexible value-based decisions in rats.

Externí odkaz: https://doaj.org/article/31622733c1f8444ca230c79f49f730a9

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Akademický článek

An Intersectional Approach to Target Neural Circuits With Cell- and Projection-Type Specificity: Validation in the Mesolimbic Dopamine System

Autor: Nefeli Kakava-Georgiadou, Maria M. Zwartkruis, Clara Bullich-Vilarrubias, Mieneke C. M. Luijendijk, Keith M. Garner, Geoffrey van der Plasse, Roger A. H. Adan

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)

Development of tools to manipulate activity of specific neurons is important for dissecting the function of neural circuits. Viral vectors and conditional transgenic animal lines that target recombinases to specific cells facilitate the successful ma

Externí odkaz: https://doaj.org/article/eec5557d9899403bacbfd9f1f042c672

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Akademický článek

Combined use of the canine adenovirus-2 and DREADD-technology to activate specific neural pathways in vivo.

Autor: Arjen J Boender, Johannes W de Jong, Linde Boekhoudt, Mieneke C M Luijendijk, Geoffrey van der Plasse, Roger A H Adan

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95392 (2014)

We here describe a technique to transiently activate specific neural pathways in vivo. It comprises the combined use of a CRE-recombinase expressing canine adenovirus-2 (CAV-2) and an adeno-associated virus (AAV-hSyn-DIO-hM3D(Gq)-mCherry) that contai

Externí odkaz: https://doaj.org/article/5f980d24999a4bbca76de1eb5407d933

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Akademický článek

Deep brain stimulation reveals a dissociation of consummatory and motivated behaviour in the medial and lateral nucleus accumbens shell of the rat.

Autor: Geoffrey van der Plasse, Regina Schrama, Sebastiaan P van Seters, Louk J M J Vanderschuren, Herman G M Westenberg

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33455 (2012)

Following the successful application of deep brain stimulation (DBS) in the treatment of Parkinson's disease and promising results in clinical trials for obsessive compulsive disorder and major depression, DBS is currently being tested in small patie

Externí odkaz: https://doaj.org/article/ea6182556b9a4e1f872c1681f8bb5062

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Zona incerta neurons projecting to the ventral tegmental area promote action initiation towards feeding

Autor: Esther M Hazelhoff, Roger A.H. Adan, Mieneke C. M. Luijendijk, Kathy C G de Git, Minke H.C. Nota, Geoffrey van der Plasse, Suzanne L. Dickson, Erik Schéle

Publikováno v: The Journal of Physiology

Key points The zona incerta (ZI) and ventral tegmental area (VTA) are brain areas that are both implicated in feeding behaviour. The ZI projects to the VTA, although it has not yet been investigated whether this projection regulates feeding.We experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5910838d41184f6a4921cc16c25b81
https://doi.org/10.1113/jp276513

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Cue and Reward Evoked Dopamine Activity Is Necessary for Maintaining Learned Pavlovian Associations

Autor: Roger A.H. Adan, Garret D. Stuber, Geert M.J. Ramakers, Bart Lodder, Siem van den Reijen, Azar Omrani, Marten P. Smidt, Timon Eekel, Geoffrey van der Plasse, Jacques P. Flores-Dourojeanni, Ruud van Zessen

Publikováno v: J Neurosci
The Journal of Neuroscience, 41(23), 5004-5014. Society for Neuroscience

Associating natural rewards with predictive environmental cues is crucial for survival. Dopaminergic (DA) neurons of the Ventral Tegmental Area (VTA) are thought to play a crucial role in this process by encoding reward prediction errors that have be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb51abca24a6f8bf61e7cae2b53606e
https://europepmc.org/articles/PMC8197637/

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Is leptin resistance the cause or the consequence of diet-induced obesity?

Autor: Céline Peterse, Roger A.H. Adan, Mieneke C. M. Luijendijk, Sanne Beerens, Kathy C G de Git, Geoffrey van der Plasse, Susanne E. la Fleur

Publikováno v: International Journal of Obesity, 42(8), 1445. Nature Publishing Group
International journal of obesity (2005), 42(8), 1445-1457. Nature Publishing Group

Background/objectives: Obesity is strongly associated with leptin resistance. It is unclear whether leptin resistance results from the (over)consumption of energy-dense diets or if reduced leptin sensitivity is also a pre-existing factor in rodent mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72643f1e51184df92d3f198979d105ba
https://pubmed.ncbi.nlm.nih.gov/29789721

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Physiological Challenges for Intracortical Electrodes

Autor: Geert M.J. Ramakers, Nick F. Ramsey, Geoffrey van der Plasse, Jitte Groothuis

Publikováno v: Brain Stimulation, Vol 7, Iss 1, Pp 1-6 (2014)

The clinical use of chronic electrode implants for measurement or stimulation of neuronal activity has increased over the past decade with the advent of deep brain stimulation and the use of brain-computer interfaces. However, despite the wide-spread

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7821b95f060791b3e44c28514568a82
https://doi.org/10.1016/j.brs.2013.07.001

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Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action

Autor: Duan Chen, Bård Kulseng, Suzanne L. Dickson, Roger A.H. Adan, Perry Barrett, Geoffrey van der Plasse, Chun-Mei Zhao, David Revesz, Karolina P. Skibicka, Elinor Ben-Menachem, Jens F. Rehfeld, Jens J. Holst, Helene Johannessen, Nikki Cassie, Yosuke Kodama

Publikováno v: Obesity surgery. 27(1)

1 Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway 2 Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eab061fc554f1a0744d2624458ede16
https://pubmed.ncbi.nlm.nih.gov/27576578

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Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action

Autor: Perry Barrett, Roger A.H. Adan, Chun-Mei Zhao, Helene Johannessen, Suzanne L. Dickson, Jens F. Rehfeld, Karolina P. Skibicka, Duan Chen, Bård Kulseng, Elinor Ben-Menachem, Nikki Cassie, Jens J. Holst, Geoffrey van der Plasse, David Revesz, Yosuke Kodama

Publikováno v: Obesity surgery. 27(1)

Recently, the US FDA has approved “vagal blocking therapy or vBLoc® therapy” as a new treatment for obesity. The aim of the present study was to study the mechanism-of-action of “VBLOC” in rat models. Rats were implanted with VBLOC, an intra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52ca8b5f7e90ee48326f4dad6ef91de
https://pubmed.ncbi.nlm.nih.gov/27628056

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