Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geoffrey W. Oddie"'
Publikováno v:
Analytical Biochemistry. 253:103-111
The interaction of monovalent forms of NC41, an anti-viral neuraminidase antibody, and the antiidiotype antibody 11-1G10 has been used as a model system for BIAcore analysis to demonstrate the potential problems resulting from the nonspecific amine c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381a64f219525e742cd5fbef9bba9234
https://doi.org/10.1006/abio.1997.2333
https://doi.org/10.1006/abio.1997.2333
Autor:
Peter J. Hudson, Glenn G. Lilley, Lesley A. Pearce, Gregory Coia, Geoffrey W. Oddie, Alexander A. Kortt
Publikováno v:
IUBMB Life. 42:1179-1188
Monomeric single chain antibody (scFv) fragments lack both the avidity of the bivalent IgG, or (Fab')2 fragment, and the effector functions conferred by the Fc domain. For certain diagnostic or therapeutic applications it may be desirable to link the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2343aeb242292b7d1970e722fc3f8b6e
https://doi.org/10.1080/15216549700203651
https://doi.org/10.1080/15216549700203651
Publikováno v:
Journal of Molecular Recognition. 10:148-158
The interaction of monovalent Fab fragments of NC10, an antiviral neuraminidase antibody, and the anti-idiotype antibody 3-2G12 has been used as a model system to demonstrate experimentally the influence of non-ideal binding effects on BIAcoreTM bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbbecfd40d1443d40fa8ff1f27205211
https://doi.org/10.1002/(sici)1099-1352(199705/06)10:3<148::aid-jmr360>3.0.co
https://doi.org/10.1002/(sici)1099-1352(199705/06)10:3<148::aid-jmr360>3.0.co
Autor:
Lesley A. Pearce, Alexander A. Kortt, Maria Lah, Robert G. Webster, Dennis W. Metzger, G J Howlett, Geoffrey W. Oddie, Airlie J. McCoy, J E Burns, Peter J. Hudson, John Leslie Atwell, C L Gruen
Publikováno v:
Protein Engineering Design and Selection. 10:423-433
Single-chain variable fragments (scFvs) of anti-neuraminidase antibody NC10 were constructed by joining the VH and VL domains with 10-residue (Gly4Ser)2 and five-residue (Gly4Ser) linkers; a zero-residue linker scFv was constructed by joining the C-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee52bb1afeb5cb5db09ac8c829028309
https://doi.org/10.1093/protein/10.4.423
https://doi.org/10.1093/protein/10.4.423
Publikováno v:
Analytical Biochemistry. 244:301-311
The interaction of human spleen ferritin with a monoclonal antibody Fab′ fragment has been studied as a model system for BIAcore analysis. In particular, the influence of nonideal binding effects has been examined both experimentally and by the the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4befcbe1b14a8e2fc4cc0ee87026b1
https://doi.org/10.1006/abio.1996.9912
https://doi.org/10.1006/abio.1996.9912
Autor:
Peter Iliades, Alexander A. Kortt, Dennis W. Metzger, David A. Dougan, Peter J. Hudson, Geoffrey W. Oddie
Publikováno v:
Journal of protein chemistry. 17(3)
A single-chain Fv (scFv) fragment of anti-idiotype antibody 11-1G10, which recognizes an idiotope of anti-neuraminidase antibody NC41, was constructed by joining VH and VL domains with a (Gly4Ser)3 linker, with a pelB leader sequence, and two C-termi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bd19ff2c6b8bc106438659d085e29d
https://pubmed.ncbi.nlm.nih.gov/9588948
https://pubmed.ncbi.nlm.nih.gov/9588948
Autor:
Pearce, Lesley A., Oddie, Geoffrey W., Coia, Gregory, Kortt, Alexander A., Hudson, Peter J., Lilley, Glenn G.
Publikováno v:
IUBMB Life; Sep1997, Vol. 42 Issue 6, p1179-1188, 10p
Publikováno v:
Journal of Molecular Recognition; May1997, Vol. 10 Issue 3, p148-158, 11p