Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Geoffrey W. Hanlon"'
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
A surge in the level and scale of antibiotic resistance has prompted renewed interest in the application of bacteriophages to treat bacterial infections. However, concerns still exist over their efficacy and safety. The cytotoxic effect of a single A
Externí odkaz:
https://doaj.org/article/d8b09a3fc3e84516a39f672fcd8a42b3
Autor:
Nina Holling, Joseph A. Hawthorne, Brian V. Jones, Lara M. Barnes, Jonathan P. Salvage, Caroline E. Jones, Cinzia Dedi, Geoffrey W. Hanlon, Bhavik Anil Patel
Publikováno v:
Fems Microbiology Letters
Proteus mirabilis is a common cause of catheter-associated urinary tract infections and frequently leads to blockage of catheters due to crystalline biofilm formation. Scanning electron microscopy (SEM) has proven to be a valuable tool in the study o
Autor:
Geoffrey W. Hanlon
Publikováno v:
International Journal of Antimicrobial Agents. 30:118-128
Bacteriophages were first used successfully to treat bacterial infections a decade before penicillin was discovered. However, the excitement that greeted those initial successes was short-lived, as a lack of understanding of basic phage biology subse
Autor:
Andrew W. Lloyd, Andrew L. Lewis, Norman C. Billingham, Geoffrey W. Hanlon, Sofie L. West, Emma J. Lobb, Jonathan P. Salvage, Steven P. Armes
Publikováno v:
Biomaterials. 25:1195-1204
The comparison of copolymers containing sulfobetaine or phosphobetaine moieties for use as potential biocompatible coatings has been investigated. Two statistical copolymers were produced by a free radical polymerisation technique, one based on a sul
Publikováno v:
Journal of Applied Microbiology. 94:1015-1023
Aims: To examine the effect on the leakage of low molecular weight cytoplasmic constituents from Staphylococcus aureus using phenolics singly and in combination, and to see if the observations could be modelled using a non-linear dose response. Metho
Autor:
Geoffrey W. Hanlon, Stephen Paul Denyer, Brenda Hall, Andrew W. Lloyd, Christopher S. Andrews
Publikováno v:
Biomaterials. 22:3225-3233
The aim of this study was to investigate in vitro adhesion of clinically relevant bacteria to standard HEMA and novel biomimetic soft contact lenses (SCL) using bioluminescent ATP assay and image analysis. Unworn SCL were incubated with Pseudomonas a
Autor:
William Rhys-Williams, Richard G. A. Faragher, M. Wassall, J.E. Hughes, Andrew W. Lloyd, Geoffrey W. Hanlon, L. Wong
Publikováno v:
Contact Lens and Anterior Eye. 23:119-123
A series of in vitro assays for determining the biocompatibility of ocular biomaterials have been developed and used to assess the differences in performance of omafilcon A, etafilcon A and nelfilcon A contact lens materials. The assays assessed bact
Publikováno v:
Journal of Pharmacy and Pharmacology. 51:207-214
Cell-surface hydrophobicity is different for Staphylococcus epidermidis cells grown under different environmental conditions; this might influence attachment and colonization of surfaces. Although a wide variety of techniques has been employed to mea
Autor:
James A. Baker, Andrew W. Lloyd, Geoffrey W. Hanlon, Florence O. McCarthy, William Rhys-Williams, Y.-F. Hung, M.J. Thomason
Publikováno v:
Enzyme and Microbial Technology. 22:281-287
Cordyceps militaris has been previously shown to invert the chirality of ( r )-2-phenylpropionic acid to its antipode in the absence of any other biotransformation. To investigate the mechanism of this unusual biotransformation. ( r , s )-[2- 2 H 1 ]
Publikováno v:
Chirality. 10:528-534
The fungus Cordyceps militaris has been previously shown to be capable of inverting the chirality of 2-phenylpropionic acid from its (R)-enantiomer to its (S)-antipode. The structure of this compound is similar to the 2-arylpropionic acid non-steroid