Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Geoffrey W Osborne"'
Autor:
Jonathan P Robson, Marc Remke, Marcel Kool, Elaine Julian, Andrey Korshunov, Stefan M Pfister, Geoffrey W Osborne, Michael D Taylor, Brandon Wainwright, Brent A Reynolds
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210665 (2019)
High morbidity and mortality are common traits of malignant tumours and identification of the cells responsible is a focus of on-going research. Many studies are now reporting the use of antibodies specific to Clusters of Differentiation (CD) cell su
Externí odkaz:
https://doaj.org/article/8f03ea00350f43f5b161b2354b598176
Autor:
Andrew B J Prowse, Fenny Chong, David A Elliott, Andrew G Elefanty, Edouard G Stanley, Peter P Gray, Trent P Munro, Geoffrey W Osborne
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52214 (2012)
Human embryonic stem cell (hESC) derivatives show promise as viable cell therapy options for multiple disorders in different tissues. Recent advances in stem cell biology have lead to the reliable production and detailed molecular characterisation of
Externí odkaz:
https://doaj.org/article/9c33bcc235e34987917f4b0979d649ed
Autor:
Hassan Azari, Geoffrey W Osborne, Takahiro Yasuda, Mohammad G Golmohammadi, Maryam Rahman, Loic P Deleyrolle, Ebrahim Esfandiari, David J Adams, Bjorn Scheffler, Dennis A Steindler, Brent A Reynolds
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20941 (2011)
Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications. However, the practical application for neuronal cell replacement is limited by
Externí odkaz:
https://doaj.org/article/b25fe7644abb492c9e154e75cd25d1bd
Autor:
Emma Sierecki, Stephen M. Mahler, Yann Gambin, Jeremy W. Prokop, Mathias Francois, Geoffrey W. Osborne, Daniel T. Rasicci, Martina L. Jones, Christopher B. Howard, Mehdi Moustaqil, Johannes Zuegg, Stephen Francis Goodall, Frank Fontaine, Sumukh Kumble
Publikováno v:
mAbs
Antibodies are routinely used to study the activity of transcription factors, using various in vitro and in vivo approaches such as electrophoretic mobility shift assay, enzyme-linked immunosorbent assay, genome-wide method analysis coupled with next
Autor:
Geoffrey W. Osborne, Wei Luan, Luke A. Hammond, Xiangyang Cui, Edmund Cotter, Suzanne Alexander, Virginia Nink, Darryl W. Eyles
Publikováno v:
Molecular Neurobiology. 55:2443-2453
Developmental vitamin D (DVD) deficiency has been proposed as an important risk factor for schizophrenia. Our previous study using Sprague Dawley rats found that DVD deficiency disrupted the ontogeny of mesencephalic dopamine neurons by decreasing th
Publikováno v:
Cytometry Part A. 87:1047-1051
Flow cytometry based electrostatic cell sorting is an important tool in the separation of cell populations. Existing instruments can sort single cells into multi-well collection plates, and keep track of cell of origin and sorted well location. Howev
Autor:
Marion E. G. Brunck, Geoffrey W. Osborne, Lars K. Nielsen, Nicholas E. Timmins, Stacey B. Andersen
Publikováno v:
Cytometry Part A. 85:1057-1064
Absolute neutrophil count (ANC) is used clinically to monitor physiological dysfunctions such as myelosuppression or infection. In the research laboratory, ANC is a valuable measure to monitor the evolution of a wide range of disease states in diseas
Autor:
Andrey Korshunov, Marcel Kool, Marc Remke, Stefan M. Pfister, Elaine Julian, Geoffrey W. Osborne, Michael D. Taylor, Brent A. Reynolds, Brandon J. Wainwright, Jonathan P. Robson
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210665 (2019)
PLoS ONE
PLoS ONE
High morbidity and mortality are common traits of malignant tumours and identification of the cells responsible is a focus of on-going research. Many studies are now reporting the use of antibodies specific to Clusters of Differentiation (CD) cell su
Autor:
Peter Lucas, S. Campbell, Andrew W. Boyd, Gert Tollesson, Craig Winter, Zara C. Bruce, Po Inglis, Wendy Findlay, Perry F. Bartlett, Geoffrey W. Osborne, Paul R. Jamieson, Rosalind L. Jeffree, Suzanne Allan, John W Wilson, Kathleen S. Ensbey, David W. Johnson, Bryan W. Day, Terrance Grant Johns, Thomas Robertson, Brett W. Stringer, David Kadrian
Publikováno v:
Cancers
Cancers, Vol 5, Iss 2, Pp 357-371 (2013)
Cancers; Volume 5; Issue 2; Pages: 357-371
Cancers, Vol 5, Iss 2, Pp 357-371 (2013)
Cancers; Volume 5; Issue 2; Pages: 357-371
Brain cancer research has been hampered by a paucity of viable clinical tissue of sufficient quality and quantity for experimental research. This has driven researchers to rely heavily on long term cultured cells which no longer represent the cancers
Autor:
Stephen M. Mahler, Sumukh Kumble, Shuo Zhang, Neetika Arora, Mohamed A. Alfaleh, Jeff Jia Cheng Hou, Martina L. Jones, David Y. Chin, Christopher B. Howard, Geoffrey W. Osborne, Michael Yeh
Publikováno v:
Scientific Reports
A critical factor in the successful isolation of new antibodies by phage display is the presentation of a correctly folded antigen. While this is relatively simple for soluble proteins which can be purified and immobilized onto a plastic surface, mem