Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geoffrey T. Woolley"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:455-460
17β-Hydroxyestra-4,9,11-trien-3-one or trenbolone is an anabolic steroid used in some meat producing countries where its use is licenced. In cattle it is metabolised into 17α-trenbolone. We were required to make 17α-[4-(14) C]trenbolone for use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5980f7667c79376499fa1fe0bd9b4c37
https://doi.org/10.1002/jlcr.3089
https://doi.org/10.1002/jlcr.3089
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:468-470
The carbon-14 radiolabels in [bisphosphinoethane-1,2- 14 C]tetrofosmin ligand were readily introduced by reacting 1,2-dibromo[U- 14 C]ethane with bis(2-ethoxyethyl)benzylphosphine (1). This was converted to the Myoview™ ligand in an overall yield o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34768bb01cf743556b6d8d515b23552c
https://doi.org/10.1002/jlcr.1199
https://doi.org/10.1002/jlcr.1199
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 56(9-10)
17β-Hydroxyestra-4,9,11-trien-3-one or trenbolone is an anabolic steroid used in some meat producing countries where its use is licenced. In cattle it is metabolised into 17α-trenbolone. We were required to make 17α-[4-(14) C]trenbolone for use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e48a27d768a733c23cae36e8b25acc2
https://pubmed.ncbi.nlm.nih.gov/24285520
https://pubmed.ncbi.nlm.nih.gov/24285520
Autor:
Basil J. Wakefield, Geoffrey T. Woolley, Anthony David Baxter, Roger F. Newton, Stanley M. Roberts
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :675-679
The threo-2-(cyclopent-2-enyl)-1-(2-oxocyclopentyl)ethanol derivatives (2) and (3) have been converted into (±)-prostaglandin I2 methyl ester and its 15-epimer. The route involved halogenoetherification, hydrodehalogenation, Baeyer–Villiger oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca445a14ff9a15a5598ca9d36a35f810
https://doi.org/10.1039/p19840000675
https://doi.org/10.1039/p19840000675
Publikováno v:
J. Chem. Soc., Chem. Commun.. :922-924
Prostacyclin (prostaglandin I2) methyl ester has been prepared; the key step was an aldol reaction between a cyclopentanone enolate and the cyclopentenyl-acetaldehyde derivative (4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0b8378649a3a52157a29f30b603369
https://doi.org/10.1039/c39810000922
https://doi.org/10.1039/c39810000922
Autor:
Anthony David Baxter, Stanley M. Roberts, Roger F. Newton, Geoffrey T. Woolley, Basil J. Wakefield
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1809
Reactions of lithium, boron, zirconium, and tin enolates derived from cyclopentanone with [4-t-butyldimethylsilyloxy-5-(3-t-butyldimethylsilyloxyoct-1-enyl)cyclopent-2-enyl]ethanal (6) gave mainly the 5R, 6R, and 5S, 6S(prostaglandin numbering), thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3407a00d2f5a2afa8e040e9c32af781b
https://doi.org/10.1039/p19830001809
https://doi.org/10.1039/p19830001809
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2603
The reduction of 6β-acylamidopenicillanates with diborane is shown to proceed by opening of the β-lactam ring to produce the corresponding amino alcohols. The chemistry of the reduction product from benzhydryl 6β-benzyloxycarbonylaminopenicillanat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f079fa900f69eb1a038e0165a42eb93f
https://doi.org/10.1039/p19840002603
https://doi.org/10.1039/p19840002603
Autor:
David W. Selby, Stanley M. Roberts, Mark A. W. Finch, Roger F. Newton, Geoffrey T. Woolley, Christopher B. Chapleo
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1847
The cyclopentenyl bromides (1) and (9) react with thiophenoxide ion in SN′syn-fashion with very high selectivity. The bromide (4) reacts with the same nucleophile to give the products of SN2 and SN2′syn-reactions. The lactones (1), (4), (15), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519f2a5ba05222c074b4661bed648d43
https://doi.org/10.1039/p19800001847
https://doi.org/10.1039/p19800001847