Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Geoffrey Schiebinger"'
Autor:
Francesco Panariello, Onelia Gagliano, Camilla Luni, Antonio Grimaldi, Silvia Angiolillo, Wei Qin, Anna Manfredi, Patrizia Annunziata, Shaked Slovin, Lorenzo Vaccaro, Sara Riccardo, Valentina Bouche, Manuela Dionisi, Marcello Salvi, Sebastian Martewicz, Manli Hu, Meihua Cui, Hannah Stuart, Cecilia Laterza, Giacomo Baruzzo, Geoffrey Schiebinger, Barbara Di Camillo, Davide Cacchiarelli, Nicola Elvassore
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Human cellular reprogramming to induced pluripotency is still an inefficient process, which has hindered studying the role of critical intermediate stages. Here we take advantage of high efficiency reprogramming in microfluidics and temporal
Externí odkaz:
https://doaj.org/article/4881a0e99d974abc86ba20b6cd9be0ad
Autor:
Aden Forrow, Geoffrey Schiebinger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve
Externí odkaz:
https://doaj.org/article/c5d6e1f958ee48a982453998f82cc8ac
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009466 (2021)
Understanding how cells change their identity and behaviour in living systems is an important question in many fields of biology. The problem of inferring cell trajectories from single-cell measurements has been a major topic in the single-cell analy
Externí odkaz:
https://doaj.org/article/13b1a2f1a5464dd59a5b4c14e5d23952
Autor:
Trevor M. Nolan, Nemanja Vukašinović, Che-Wei Hsu, Jingyuan Zhang, Isabelle Vanhoutte, Rachel Shahan, Isaiah W. Taylor, Laura Greenstreet, Matthieu Heitz, Anton Afanassiev, Ping Wang, Pablo Szekely, Aiden Brosnan, Yanhai Yin, Geoffrey Schiebinger, Uwe Ohler, Eugenia Russinova, Philip N. Benfey
Publikováno v:
SCIENCE
Science
Science
Brassinosteroids are plant steroid hormones that regulate diverse processes, such as cell division and cell elongation, through gene regulatory networks that vary in space and time. By using time series single-cell RNA sequencing to profile brassinos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b15789f287c4c12dcac9661bfd39ff1
https://biblio.ugent.be/publication/01GX3832S6RHTHB2KPR99Z4JYS
https://biblio.ugent.be/publication/01GX3832S6RHTHB2KPR99Z4JYS
Autor:
Trevor M Nolan, Nemanja Vukašinović, Che-Wei Hsu, Jingyuan Zhang, Isabelle Vanhoutte, Rachel Shahan, Isaiah W Taylor, Laura Greenstreet, Matthieu Heitz, Anton Afanassiev, Ping Wang, Pablo Szekely, Aiden Brosnan, Yanhai Yin, Geoffrey Schiebinger, Uwe Ohler, Eugenia Russinova, Philip N Benfey
Brassinosteroids (BRs) are plant steroid hormones that regulate diverse processes such as cell division and cell elongation. BRs control thousands of genes through gene regulatory networks that vary in space and time. By using time-series single-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af3da20da4212083fc952af702e07251
https://doi.org/10.1101/2022.09.16.508001
https://doi.org/10.1101/2022.09.16.508001
Autor:
Vijay Kuchroo, Yu Hou, Martin LaFleur, Linglin Huang, Conner Lambden, Pratiksha Thakore, Kathryn Geiger-Schuller, Ruihan Tang, Jingwen Shi, Rocky Barilla, Ayshwarya Subramanian, Antonia Wallrapp, Hee Sun Choi, Yoon-Chul Kye, Orr Ashenbrg, Geoffrey Schiebinger, John Doench, Aviv Regev, Arlene Sharpe
The balance between T helper type 1 (Th1) cells and other Th cells is critical for antiviral and anti-tumor responses, but how this fine balance is achieved remains poorly understood. Here, we dissected the dynamic regulation of Th1 cell differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f73a53d2c34de40f858520400f4428e
https://doi.org/10.21203/rs.3.rs-1953978/v1
https://doi.org/10.21203/rs.3.rs-1953978/v1
Autor:
Arina Piechka, Ghazal Ebrahimi, Meghan Robinson, Anton Afanassiev, Geoffrey Schiebinger, Eric Belanger, Faraz Hach, Ryan Flannigan
Publikováno v:
Journal of Urology. 207
Autor:
Laura Greenstreet, Anton Afanassiev, Yusuke Kijima, Matthieu Heitz, Soh Ishiguro, Samuel King, Nozomu Yachie, Geoffrey Schiebinger
We present GPS-seq, a theoretical framework that enables massively scalable, optics-free spatial transcriptomics. GPS-seq combines data from high-throughput sequencing with manifold learning to obtain the spatial transcriptomic landscape of a given t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0cca02366f1eb28e28d0a5553e794c
https://doi.org/10.1101/2022.03.22.485380
https://doi.org/10.1101/2022.03.22.485380
Autor:
Alejandro Berrio, Anton Afanassiev, Geoffrey Schiebinger, David R. McClay, Abdull J. Massri, Gregory A. Wray, Laura Greenstreet
Publikováno v:
Development
Using scRNA-seq coupled with computational approaches, we studied transcriptional changes in cell states of sea urchin embryos during development to the larval stage. Eighteen closely spaced time points were taken during the first 24 h of development
Autor:
Enrico Moiso, Anton Afanassiev, Jennifer Whangbo, Edroaldo Lummertz da Rocha, Geoffrey Schiebinger, Vincent L. Butty, Stephen Zhang, Aviv Regev, Dahai Wang, Stella T. Chou, George Q. Daley, Jideofor Ezike, Salil Garg, R. Grant Rowe, Vivian Morris, Laura Greenstreet, Hojun Li, Guinevere Connelly
Hematopoiesis is a process of constitutive regeneration whereby hematopoietic stem and progenitor cells (HSPCs) replenish mature blood cells. During maturation and aging, HSPCs shift their output to support the demands of prenatal development and pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::517a5e7154b566dca5a9ffa73f2d1864
https://doi.org/10.1101/2021.08.25.457678
https://doi.org/10.1101/2021.08.25.457678