Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Geoffrey S Waldo"'
Autor:
Daniil M Prigozhin, Inna V Krieger, John P Huizar, Daniela Mavrici, Geoffrey S Waldo, Li-Wei Hung, James C Sacchettini, Thomas C Terwilliger, Tom Alber
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116249 (2014)
Beta-lactam antibiotics target penicillin-binding proteins including several enzyme classes essential for bacterial cell-wall homeostasis. To better understand the functional and inhibitor-binding specificities of penicillin-binding proteins from the
Externí odkaz:
https://doaj.org/article/1bbc03da4e664bf7ae5ff99510a4bd03
Autor:
Wen Wei, Leonie Lampe, Sungha Park, Bhavana S Vangara, Geoffrey S Waldo, Stephanie Cabantous, Sarah S Subaran, Dongmei Yang, Edward G Lakatta, Li Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50736 (2012)
The receptor for advanced glycation end products (RAGE) on the cell surface transmits inflammatory signals. A member of the immunoglobulin superfamily, RAGE possesses the V, C1, and C2 ectodomains that collectively constitute the receptor's extracell
Externí odkaz:
https://doaj.org/article/93280013908749349a09c72bc3c48e96
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25727 (2011)
Antibody fragments are easily isolated from in vitro selection systems, such as phage and yeast display. Lacking the Fc portion of the antibody, they are usually labeled using small peptide tags recognized by antibodies. In this paper we present an e
Externí odkaz:
https://doaj.org/article/0c042e9ff1714f0ebaefad9539444eb6
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2387 (2008)
The GFP folding reporter assay uses a C-terminal GFP fusion to report on the folding success of upstream fused polypeptides. The GFP folding assay is widely-used for screening protein variants with improved folding and solubility, but truncation arti
Externí odkaz:
https://doaj.org/article/9606a9d9987541b88c933c02ae5a326e
Autor:
Cécile Bon, Stéphanie Cabantous, Sylviane Julien, Valérie Guillet, Christian Chalut, Julie Rima, Yoann Brison, Wladimir Malaga, Angelique Sanchez-Dafun, Sabine Gavalda, Annaïk Quémard, Julien Marcoux, Geoffrey S. Waldo, Christophe Guilhot, Lionel Mourey
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Type I polyketide synthases (PKSs) are multifunctional enzymes responsible for the biosynthesis of a group of diverse natural compounds with biotechnological and pharmaceutical interest called polyketides. The diversity of polyket
Externí odkaz:
https://doaj.org/article/ce957ac87b34489ba429e3036d0705f9
Autor:
Nileena Velappan, Sofiya Micheva-Viteva, Samantha H. Adikari, Geoffrey S. Waldo, Antonietta M. Lillo, Andrew R.M. Bradbury
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Interactions between the cytoplasmic domains of viral transmembrane proteins and host machinery often determine the outcome of viral infection. The M2 protein of influenza A has been identified as a key player in autophagy-mediated viral replication.
Externí odkaz:
https://doaj.org/article/bfd2f03c531744d29fb275e897d72607
Autor:
Nileena Velappan, Hau B. Nguyen, Sofiya Micheva-Viteva, Daniel Bedinger, Chunyan Ye, Betty Mangadu, Austin J. Watts, Robert Meagher, Steven Bradfute, Bin Hu, Geoffrey S. Waldo, Antonietta M. Lillo
Publikováno v:
Bioengineered. 13:12598-12624
Here, we describe the isolation of 18 unique anti SARS-CoV-2 human single-chain antibodies from an antibody library derived from healthy donors. The selection used a combination of phage and yeast display technologies and included counter-selection s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83321dc171ab84784f512d8becf8539
https://doi.org/10.1080/21655979.2022.2076390
https://doi.org/10.1080/21655979.2022.2076390
Autor:
Shounak Banerjee, Yury Minko, Elizabeth S Anaya, Zachary J Sasiene, Jurgen G Schmidt, Charlie E M Strauss, Geoffrey S Waldo
Measuring the entropic properties of polymers such as proteins is critical to accurate prediction of their functional properties. However, the measurement of configurational entropy is possible only by low throughput techniques such as calorimetry, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd76e95d847e6546d1f741392d6fced
https://doi.org/10.1101/2022.11.07.515508
https://doi.org/10.1101/2022.11.07.515508
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Split green fluorescent protein (GFP) has been used in a panoply of cellular biology applications to study protein translocation, monitor protein solubility and aggregation, detect protein–protein interactions, enhance protein crystallization, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088dded60e51b18f7bb2ea05f404aae1
https://doi.org/10.1038/s41598-021-98149-8
https://doi.org/10.1038/s41598-021-98149-8