Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Geoffrey S, Gottlieb"'
Autor:
James P Hughes, Helen Y Chu, Lea M Starita, Peter D Han, Caitlin R Wolf, Geoffrey S Gottlieb, Marco Carone, Zachary Acker, Ana A Weil, Julia Catherine Bennett, Jessica O’Hanlon, Devon McDonald, Tessa Wright, Kyle G Luiten, Lani Regelbrugge, Kathryn M McCaffrey, Brian Pfau
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Objective We aimed to evaluate the feasibility and utility of an unsupervised testing mechanism, in which participants pick up a swab kit, self-test (unsupervised) and return the kit to an on-campus drop box, as compared with supervised self-testing
Externí odkaz:
https://doaj.org/article/60a395f9b13b4ddfa518d2fcce6a20e5
Autor:
Ana A. Weil, Kyle G. Luiten, Amanda M. Casto, Julia C. Bennett, Jessica O’Hanlon, Peter D. Han, Luis S. Gamboa, Evan McDermot, Melissa Truong, Geoffrey S. Gottlieb, Zack Acker, Caitlin R. Wolf, Ariana Magedson, Eric J. Chow, Natalie K. Lo, Lincoln C. Pothan, Devon McDonald, Tessa C. Wright, Kathryn M. McCaffrey, Marlin D. Figgins, Janet A. Englund, Michael Boeckh, Christina M. Lockwood, Deborah A. Nickerson, Jay Shendure, Trevor Bedford, James P. Hughes, Lea M. Starita, Helen Y. Chu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
This study presents results from a SARS-CoV-2 genomic surveillance study at a university campus in which ~2,000 samples were sequenced over five months. The authors document the replacement of Delta with Omicron as the dominant variant, and describe
Externí odkaz:
https://doaj.org/article/92322f8983524d7dad8b3aee0ac192b1
Autor:
Robert A Smith, Dana N Raugi, Robert S Nixon, Jennifer Song, Moussa Seydi, Geoffrey S Gottlieb, University of Washington-Senegal HIV-2 Study Group
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280568 (2023)
GSK2838232 (GSK232) is a novel maturation inhibitor that blocks the proteolytic cleavage of HIV-1 Gag at the junction of capsid and spacer peptide 1 (CA/SP1), rendering newly-formed virions non-infectious. To our knowledge, GSK232 has not been tested
Externí odkaz:
https://doaj.org/article/f97b6da26a0148138484694dd29dc288
Autor:
Dana N. Raugi, Khardiata Diallo, Mouhamadou Baïla Diallo, Dominique Faye, Ousseynou Cisse, Robert A. Smith, Fatima Sall, El Hadji Ibrahima Sall, Khadim Faye, Jean Philippe Diatta, Binetou Diaw, Jacques Sambou, Jean Jacques Malomar, Stephen E. Hawes, Moussa Seydi, Geoffrey S. Gottlieb, for the University of Washington-Senegal HIV-2 Study Group
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Second-line treatment of HIV-2 in resource-limited settings (RLS) is complicated by a lack of controlled trial data, limited availability of HIV-2-active antiretroviral drugs, and inadequate access to drug resistance testing. We c
Externí odkaz:
https://doaj.org/article/62636ad8a74d4c82b9e4f1a5227e2f41
Autor:
Steven M. Goodreau, Sarah E. Stansfield, John E. Mittler, James T. Murphy, Neil F. Abernethy, Geoffrey S. Gottlieb, Molly C. Reid, Juandalyn C. Burke, Emily D. Pollock, Joshua T. Herbeck
Publikováno v:
Epidemics, Vol 41, Iss , Pp 100629- (2022)
Background: Set-point viral load (SPVL) correlates with the age at which people acquire HIV. Although immunosenescence may seem like a parsimonious explanation for this, it does not easily explain the observation that the relationship between age and
Externí odkaz:
https://doaj.org/article/d02f0bf8ce544b9294de39ea48ecfaf5
Autor:
Noelle A. Benzekri, Jacques F. Sambou, Sanou Ndong, Mouhamadou Baïla Diallo, Ibrahima Tito Tamba, Dominique Faye, Ibrahima Sall, Jean Philippe Diatta, Khadim Faye, Ousseynou Cisse, Fatima Sall, Ndèye Fatou Ngom Guèye, Cheikh T. Ndour, Papa Salif Sow, Jean Jacques Malomar, Stephen E. Hawes, Moussa Seydi, Geoffrey S. Gottlieb
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Understanding the impact of food insecurity on HIV outcomes is critical for the development and implementation of effective, evidence-based interventions to address food insecurity and improve the HIV care cascade. We conducted a
Externí odkaz:
https://doaj.org/article/2f7a0652365c491f934f77424192dd9d
Autor:
Kathryn Peebles, John E. Mittler, Steven M. Goodreau, James T. Murphy, Molly C. Reid, Neil Abernethy, Geoffrey S. Gottlieb, Ruanne V. Barnabas, Joshua T. Herbeck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Pathogen populations can evolve in response to selective pressure from vaccine-induced immune responses. For HIV, models predict that viral adaptation, either via strain replacement or selection on de novo mutation, may rapidly reduce the ef
Externí odkaz:
https://doaj.org/article/bce81ff0a8e8480b8372dd88288e5978
Autor:
Noelle A. Benzekri, Jacques F. Sambou, Sanou Ndong, Ibrahima Tito Tamba, Dominique Faye, Mouhamadou Baïla Diallo, Jean Phillippe Diatta, Khadim Faye, Ibrahima Sall, Fatima Sall, Noël Magloire Manga, Jean Jacques Malomar, Cheikh T. Ndour, Stephen E. Hawes, Moussa Seydi, Geoffrey S. Gottlieb
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background The WHO guidelines for the management of advanced HIV disease recommend a package of care consisting of rapid initiation of antiretroviral therapy (ART), enhanced screening and diagnosis of tuberculosis (TB) and cryptococcal menin
Externí odkaz:
https://doaj.org/article/f690d18f43f34cdfa11bd1ee396cb38a
Autor:
Sarah E. Stansfield, John E. Mittler, Geoffrey S. Gottlieb, James T. Murphy, Deven T. Hamilton, Roger Detels, Steven M. Wolinsky, Lisa P. Jacobson, Joseph B. Margolick, Charles R. Rinaldo, Joshua T. Herbeck, Steven M. Goodreau
Publikováno v:
Epidemics, Vol 26, Iss , Pp 68-76 (2019)
Background: HIV-1 set point viral load (SPVL) is a highly variable trait that influences disease progression and transmission risk. Men who are exclusively insertive (EI) during anal intercourse require more sexual contacts to become infected than ex
Externí odkaz:
https://doaj.org/article/508504e5b4f0423f92fb968dffcd176a
Autor:
John E Mittler, James T Murphy, Sarah E Stansfield, Kathryn Peebles, Geoffrey S Gottlieb, Neil F Abernethy, Molly C Reid, Steven M Goodreau, Joshua T Herbeck
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 12, p e1007561 (2019)
Predominantly heterosexual HIV-1 epidemics like those in sub-Saharan Africa continue to have high HIV incidence in young people. We used a stochastic, agent-based model for age-disparate networks to test the hypothesis that focusing uptake and retent
Externí odkaz:
https://doaj.org/article/58b2431962a7409780a3a8aaf325492f