Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Geoffrey Pecar"'
Autor:
Geoffrey Pecar, Simeng Liu, Jagmohan Hooda, Jennifer M. Atkinson, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract RET, a single-pass receptor tyrosine kinase encoded on human chromosome 10, is well known to the field of developmental biology for its role in the ontogenesis of the central and enteric nervous systems and the kidney. In adults, RET alterat
Externí odkaz:
https://doaj.org/article/63fb5f99de204429853b78720610f235
Abstract P6-14-02: Hope for OTHERS – An organ donation program for metastatic breast cancer research
Autor:
Steffi Oesterreich, Lori Miller, Margaret Q. Rosenzweig, Tanner L. Bartholow, Megan Yates, Ashuvinee Elangovan, Laura Savariau, Allison N. Casey, Nolan Priedigkeit, Kai Ding, Abdalla Wedn, Jie Bin Liu, Daniel D. Brown, Tara Hyder, Geoffrey Pecar, Neil Carleton, Humberto Trejo Bittar, Daniel Geisler, Oscar Lopez-Nunez, Amanda M. Clark, Alan Wells, Partha Roy, Shannon Puhalla, Naomi Howard, Christine Needles, Susan Trent, Stephanie Walker, Christine Hodgdon, Rohit Bhargava, Jennifer M. Atkinson, Adrian V. Lee
Publikováno v:
Cancer Research. 83:P6-14
Background: Previous studies have shown that rapid autopsies (RA) provide a unique opportunity for tissue collection from patients who succumb to the disease. Because cancer patients are unable to donate their organs to other people, this program pro
Autor:
Lyuda Lukashova, Rebecca J. Watters, Kurt R. Weiss, Peter C. Lucas, Benjamin M Martin, Shiming Jiang, Alejandro Morales-Restrepo, Peter N. Mittwede, Geoffrey Pecar, Adrian V. Lee, Deborah L. Galson, Ryan J. Hartmaier, Li Zhu, Peter G. Alexander, George C. Tseng, Kostas Verdelis, Yuqing Chen, Feiqi Lu, Brendan Lee, Steffi Oesterreich, Margaret L. Hankins
Publikováno v:
Endocrinology
The steroid receptor coactivator-1 (SRC-1) is a nuclear receptor co-activator, known to play key roles in both estrogen response in bone and in breast cancer metastases. We previously demonstrated that the P1272S single nucleotide polymorphism (SNP;
Autor:
Geoffrey Pecar, Jennifer M. Atkinson, Ashuvinee Elangovan, Lauren Walheim, Susan M. Farabaugh, Beate C. Litzenburger, Adrian V. Lee
Publikováno v:
Dev Biol
Breast tumors display tremendous heterogeneity in part due to varying molecular alterations, divergent cells of origin, and differentiation. Understanding where and how this heterogeneity develops is likely important for effective breast cancers erad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969e1f722245e44cd5398548d26000e8
https://europepmc.org/articles/PMC7297516/
https://europepmc.org/articles/PMC7297516/
Autor:
Geoffrey Pecar, Simeng Liu, Jennifer M. Atkinson, Steffi Oesterreich, Fangyuan Chen, Jagmohan Hooda, Adrian V. Lee
Publikováno v:
Cancer Research. 81:2864-2864
Brain metastases (BrM) are reported in approximately 10-30% of breast cancer patients with a poor median overall survival of 8.5 months. Current therapeutic strategies are mostly limited to surgery, chemotherapy and radiotherapy, making the study of