Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Geoffrey P. Dobson"'
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract For decades, left ventricular ejection fraction (LVEF
Externí odkaz:
https://doaj.org/article/9c42ee1cd2bb4ff38d74c81596824786
Publikováno v:
Bone & Joint Research, Vol 13, Iss 6, Pp 279-293 (2024)
Aims: Adenosine, lidocaine, and Mg2+ (ALM) therapy exerts differential immuno-inflammatory responses in males and females early after anterior cruciate ligament (ACL) reconstruction (ACLR). Our aim was to investigate sex-specific effects of ALM thera
Externí odkaz:
https://doaj.org/article/10fe36b123af4fec8523c0e552d4fefa
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Severe infection and sepsis are medical emergencies. High morbidity and mortality are linked to CNS dysfunction, excessive inflammation, immune compromise, coagulopathy and multiple organ dysfunction. Males appear to have a higher risk of mo
Externí odkaz:
https://doaj.org/article/893a9282f1f64fc18da2a96432b5fd1b
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Background Early dysregulation of local and systemic inflammatory and immune responses is implicated in the pathogenesis of fibrotic and degenerative complications after anterior cruciate ligament reconstruction (ACLR) surgery. In other surg
Externí odkaz:
https://doaj.org/article/615993c7e6404fadac89eef3a13bafd1
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Introduction The binding of drugs to plasma proteins is an important consideration in drug development. We have reported that the dose of adenosine, lidocaine, and magnesium (ALM) fluid therapy for resuscitation from hemorrhagic shock is nea
Externí odkaz:
https://doaj.org/article/fc4bdd7d769e44359f0586de402a6c56
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
If a trauma (or infection) exceeds the body’s evolutionary design limits, a stress response is activated to quickly restore homeostasis. However, when the injury severity score is high, death is often imminent. The goal of this review is to provide
Externí odkaz:
https://doaj.org/article/9ed6ba855f0448f5a711c85e900987dd
Autor:
Jodie L. Morris, Hayley L. Letson, Peter McEwen, Erik Biros, Constantin Dlaska, Kaushik Hazratwala, Matthew Wilkinson, Geoffrey P. Dobson
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-15 (2021)
Abstract Background Dysregulated inflammatory responses are implicated in the pathogenesis of joint stiffness and arthrofibrosis following total knee arthroplasty (TKA). The purpose of this study was to compare the effects of intra-articular (IA) adm
Externí odkaz:
https://doaj.org/article/ae1742be39814d9bbeb8235e83400beb
Autor:
Nina Sarah Hoeger, Thomas Mittlmeier, Brigitte Vollmar, Ioannis Stratos, Geoffrey P. Dobson, Robert Rotter
Publikováno v:
Biology, Vol 12, Iss 6, p 870 (2023)
Skeletal muscle trauma is a common injury with a range of severity. Adenosine, lidocaine and Mg2+ (ALM) is a protective solution and improves tissue perfusion and coagulopathy. Male Wistar rats were anesthetized and subjected to standardized skeletal
Externí odkaz:
https://doaj.org/article/f7e5ae501c594be48fda82f838557e1c
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Little is known on the sex-specific healing responses after an anterior cruciate ligament (ACL) rupture. To address this, we compared male and female Sprague-Dawley rats following non-surgical ACL rupture. Hematology, inflammation, joint swelling, ra
Externí odkaz:
https://doaj.org/article/7ab9c1ef6aeb47049b81103a60b4e634
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Over the years, many explanations have been put forward to explain early and late deaths following hemorrhagic trauma. Most include single-event, sequential contributions from sympathetic hyperactivity, endotheliopathy, trauma-induced coagulopathy (T
Externí odkaz:
https://doaj.org/article/f75281fbd12a44409d9ac53eae198bdf