Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Geoffrey Metcalf"'
Autor:
Will Paces, Elliott Ergon, Elizabeth Bueche, G. Dave Young, Vitria Adisetiyo, Cris Luengo, Meredith James, Charles Caldwell, Dannah Miller, Morgan Wambaugh, Geoffrey Metcalf, Roberto Gianani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract PD-L1 (22C3) checkpoint inhibitor therapy represents a mainstay of modern cancer immunotherapy for non-small cell lung cancer (NSCLC). In vitro diagnostic (IVD) PD-L1 antibody staining is widely used to predict clinical intervention efficacy
Externí odkaz:
https://doaj.org/article/fcfbd68415114c36b101185dfdc94015
Publikováno v:
Stroke. 25:1241-1244
The competitive N-methyl-D-aspartate antagonist MDL-100,453 was used to determine whether a neuroprotective effect is demonstrable when the drug is administered beginning 30 minutes after the initiation of focal ischemia and whether the effect is rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f33f5a113cbea1cd66c4399dac63bba
https://doi.org/10.1161/01.str.25.6.1241
https://doi.org/10.1161/01.str.25.6.1241
Publikováno v:
Pharmacology Biochemistry and Behavior. 16:725-729
Continuous intraperitoneal infusion of opiates into rats has been investigated as a method of predicting the physical dependence liability of such drugs in humans. The method differs from and has several advantages over previous methods. Using the sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887431fa585acc2c07e0e2271c0539e3
https://doi.org/10.1016/0091-3057(82)90225-8
https://doi.org/10.1016/0091-3057(82)90225-8
Publikováno v:
Regulatory Peptides. 3:193-206
l -Pyroglutamyl- l -histidyl- l -3,3-dimethylprolineamide (Pyr-His-Dmp·NH2; RX 77368) a stabilised analogue of thyrotropin-releasing hormone (TRH) has been examined for neuropharmacological effects in animal tests. The compound was more potent than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999a135990191651af0c4e418cc5d563
https://doi.org/10.1016/0167-0115(82)90125-2
https://doi.org/10.1016/0167-0115(82)90125-2
Publikováno v:
European Journal of Pharmacology. 143:361-371
The behavioral effects of several new anxiolytics and putative anxiolytics were evaluated in two tests sensitive for anxiolytic activity. In the first test, rats were trained to lever-respond for sweetened milk under a multiple variable-interval fixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90148541bfab0901907036b01e06731a
https://doi.org/10.1016/0014-2999(87)90460-2
https://doi.org/10.1016/0014-2999(87)90460-2
Autor:
Geoffrey Metcalf
Publikováno v:
Brain Research Reviews. 4:389-408
The biological properties of several analogues of TRH (Pyr-His-Pro X NH2) are reviewed. Analogues discussed include those with modifications to the Pyr moiety (e.g. DN-1417, CG 3509 and CG 3703), the Pro moiety (e.g. RX 77368) and MK-771 which has bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f6490d0185f1a253adfbdbc60ebd94
https://doi.org/10.1016/0165-0173(82)90012-1
https://doi.org/10.1016/0165-0173(82)90012-1
Autor:
IVOR M. D. JACKSON, GEOFFREY METCALF
Publikováno v:
Annals of the New York Academy of Sciences. 553:473-475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7916ff9979abe23da984a398345c206d
https://doi.org/10.1111/j.1749-6632.1989.tb54512.x
https://doi.org/10.1111/j.1749-6632.1989.tb54512.x
Autor:
GEOFFREY METCALF, IVOR M. D. JACKSON
Publikováno v:
Annals of the New York Academy of Sciences. 553:xv-xvii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b0d888ba11462426d72c6ff5526a386
https://doi.org/10.1111/j.1749-6632.1989.tb46626.x
https://doi.org/10.1111/j.1749-6632.1989.tb46626.x
Autor:
Geoffrey Metcalf
Publikováno v:
Annals of the New York Academy of Sciences. 553:311-313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef45852c80ab29de40bbb3c8d685382
https://doi.org/10.1111/j.1749-6632.1989.tb54498.x
https://doi.org/10.1111/j.1749-6632.1989.tb54498.x
Two types of opiate receptor, the μ (morphine) and k (ketocyclazocine) receptors have been distinguished both in vivo (1,2) and in vitro (3) The k receptor agonists are devoid of antagonist activity and do not substitute for morphine in the morphine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::214378557a35a3b8c14240a9458d9834
https://doi.org/10.1016/b978-0-08-025488-3.50031-3
https://doi.org/10.1016/b978-0-08-025488-3.50031-3
