Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Geoffrey M. Schultz"'
Autor:
Noriyuki Miyama, Monica M. Dua, Geoffrey M. Schultz, Hisanori Kosuge, Masahiro Terashima, Laura J. Pisani, Ronald L. Dalman, Michael V. McConnell
Publikováno v:
Molecular Imaging, Vol 11 (2012)
Macrophage infiltration is a prominent feature of abdominal aortic aneurysm (AAA) progression. We used a combined imaging approach with bioluminescence (BLI) and magnetic resonance imaging (MRI) to study macrophage homing and accumulation in experime
Externí odkaz:
https://doaj.org/article/41522f6de8d245479af466055ca02802
Autor:
Yasunori Iida, Baohui Xu, Geoffrey M Schultz, Vinca Chow, Julie J White, Shola Sulaimon, Ayala Hezi-Yamit, Susan Rea Peterson, Ronald L Dalman
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49642 (2012)
Despite the importance of the renin-angiotensin (Ang) system in abdominal aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical aneurysm progression remain controversial and unproven. We compared the relative effica
Externí odkaz:
https://doaj.org/article/dac9084fd68f4620b256c59cde18a1a1
Autor:
Eiketsu Sho, Mien Sho, Geoffrey M. Schultz, Ronald L. Dalman, Janice J. Yeung, Noriyuki Miyama, Monica M. Dua, Tomoko Asagami
Publikováno v:
Journal of Vascular Surgery. 52(4):975-983
Diabetes mellitus (DM) is associated with reduced progression of abdominal aortic aneurysm (AAA) disease. Mechanisms responsible for this negative association remain unknown. We created AAAs in hyperglycemic mice to examine the influence of serum glu
Autor:
Griffith R. Harsh, Mitomu Kioi, Hannes Vogel, Robert M. Hoffman, J. Martin Brown, Geoffrey M. Schultz
Publikováno v:
Journal of Clinical Investigation. 120:694-705
Despite the high doses of radiation delivered in the treatment of patients with glioblastoma multiforme (GBM), the tumors invariably recur within the irradiation field, resulting in a low cure rate. Understanding the mechanism of such recurrence is t
Autor:
Yoko Kojima, Euan A. Ashley, Phillip Tsao, Geoffrey M. Schultz, Thomas Quertermous, Ronald L. Dalman, Nicholas J. Leeper, Maureen M. Tedesco, Ramendra K. Kundu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 296:H1329-H1335
Apelin is a potent inodilator with recently described antiatherogenic properties. We hypothesized that apelin might also attenuate abdominal aortic aneurysm (AAA) formation by limiting disease-related vascular wall inflammation. C57BL/6 mice implante
Autor:
Ronald L. Dalman, Charles A. Taylor, Geoffrey M. Schultz, Janice J. Yeung, Andrea S. Les, Robert J. Herfkens
Publikováno v:
Cardiovascular engineering and technology. 1(1)
Purpose Hemodynamic forces are thought to play a critical role in abdominal aortic aneurysm (AAA) growth. In silico and in vitro simulations can be used to study these forces, but require accurate aortic geometries and boundary conditions. Many AAA s
Autor:
Geoffrey M. Schultz, Julie J. White, Baohui Xu, Ayala Hezi-Yamit, Shola Sulaimon, Ronald L. Dalman, Yasunori Iida, Susan Rea Peterson, Vinca Chow
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e49642 (2012)
PLoS ONE, Vol 7, Iss 12, p e49642 (2012)
Background Despite the importance of the renin-angiotensin (Ang) system in abdominal aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical aneurysm progression remain controversial and unproven. We compared the rela
Autor:
Ronald L. Dalman, Hisanori Kosuge, Geoffrey M. Schultz, Noriyuki Miyama, Masahiro Terashima, Michael V. McConnell, Monica M. Dua, Laura Pisani
Publikováno v:
Journal of Cardiovascular Magnetic Resonance
Macrophage infiltration is a prominent feature of abdominal aortic aneurysm (AAA) progression. We used a multimodality imaging approach - magnetic resonance (MRI) and bioluminescence (BLI) - to study macrophage homing and accumulation in experimental
Autor:
Noriyuki Miyama, Monica M. Dua, Geoffrey M. Schultz, Ronald L. Dalman, Mien Sho, Junya Azuma, John Morser
Background Extracellular matrix degradation is a sentinel pathologic feature of abdominal aortic aneurysm (AAA) disease. Diabetes mellitus, a negative risk factor for AAA, may impair aneurysm progression through its influence on the fibrinolytic syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5827719e9c106e66aaef0e467727016
https://europepmc.org/articles/PMC2905480/
https://europepmc.org/articles/PMC2905480/
Autor:
John Morser, Lawrence L.K. Leung, Geoffrey M. Schultz, Maureen M. Tedesco, Timothy Myles, Eiketsu Sho, Ronald L. Dalman, Xiao-Yan Du, Shadi Sharif, Toshihiko Nishimura
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 30(7)
Objective—To determine whether procarboxypeptidase B (pCPB)−/−mice are susceptible to accelerated abdominal aortic aneurysm (AAA) development secondary to unregulated OPN-mediated mural inflammation in the absence of CPB inhibition.Methods and