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pro vyhledávání: '"Geoffrey M. H. Walker"'
Autor:
Suju Mathew, Adam Scott, Gemma Scotney, Graham Checksfield, Peter J. Dunn, Doug Critcher, Alexander Wilder, Stuart Field, Geoffrey M. H. Walker, Roger M. Howard, Laurence James Harris, Georges Assaf
Publikováno v:
Green Chem.. 14:123-129
The Pfizer Green Chemistry metrics program is described and exemplified with a case history involving the synthesis of (S,S)-reboxetine succinate. The initial route used a classical resolution approach and generated high levels of waste. This route w