Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Geoffrey M, Kapler"'
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 491 (2023)
Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of Tetrahymena thermophila. Subsequently, all macronucl
Externí odkaz:
https://doaj.org/article/5c44d8634c314489a4bd16552c40df9b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cell synchronization is a powerful tool to understand cell cycle events and its regulatory mechanisms. Counter-flow centrifugal elutriation (CCE) is a more generally desirable method to synchronize cells because it does not significantly alter cell b
Externí odkaz:
https://doaj.org/article/217ffd29447a4019b3ea7f9ceed3eba4
Autor:
Fei Liu, Jian Q. Feng, Geoffrey M. Kapler, Michael A. Deveau, Courtney L. Baetge, Jun Wang, Bo Hai, Linying Zhang, Qingguo Zhao
Figure S1-9, Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4c3db455baffda814226421261c04c
https://doi.org/10.1158/0008-5472.22427242
https://doi.org/10.1158/0008-5472.22427242
Autor:
Fei Liu, Jian Q. Feng, Geoffrey M. Kapler, Michael A. Deveau, Courtney L. Baetge, Jun Wang, Bo Hai, Linying Zhang, Qingguo Zhao
Irreversible hypofunction of salivary glands is a common side effect of radiotherapy for head and neck cancer and is difficult to remedy. Recent studies indicate that transient activation of Hedgehog signaling rescues irradiation-impaired salivary fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9e1544cacfb8e78bf91414f78fe094
https://doi.org/10.1158/0008-5472.c.6512602.v1
https://doi.org/10.1158/0008-5472.c.6512602.v1
Autor:
Domenico F Galati, Gaea Turman, Erica Branham, Courtney Yoshiyama, Maya Matsumoto, Jason Sasser, Megan N Morris, Erin Tessier, Megan L Kelly, Geoffrey M. Kapler, Kerry Roberts-Nygren, Daniel A. Pollard, Brian Miller, Christina Mong, Matthew S. Zinkgraf, Hung Quang Dang, Suzanne R Lee
Publikováno v:
Molecular Biology of the Cell. 32:1335-1346
Endogenous RNA interference (RNAi) pathways regulate a wide range of cellular processes in diverse eukaryotes, yet in the ciliated eukaryote, Tetrahymena thermophila, the cellular purpose of RNAi pathways that generate ∼23-24 nucleotide (nt) small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9021aacd7b891fc666e4ea9e912a418d
https://doi.org/10.1091/mbc.e20-10-0631
https://doi.org/10.1091/mbc.e20-10-0631
Autor:
Geoffrey M Kapler, Steve A Maxwell, Barbara Gastel, Gregg B Wells, Sheila Green, Robin Fuchs-Young, Gloria M Conover, Catherine Pepper, David P Huston
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 97(5)
Problem Understanding and communicating medical advances driven by basic research, and acquiring foundational skills in critically appraising and communicating translational basic research literature that affects patient care, are challenging for med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c33a4d7606c311b31932db8e28f472
https://pubmed.ncbi.nlm.nih.gov/34789666
https://pubmed.ncbi.nlm.nih.gov/34789666
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005405 (2015)
The intra-S phase checkpoint kinase of metazoa and yeast, ATR/MEC1, protects chromosomes from DNA damage and replication stress by phosphorylating subunits of the replicative helicase, MCM2-7. Here we describe an unprecedented ATR-dependent pathway i
Externí odkaz:
https://doaj.org/article/76a45235fbef452cadad97c4a052d0ce
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004875 (2015)
The Tetrahymena thermophila DNA replication machinery faces unique demands due to the compartmentalization of two functionally distinct nuclei within a single cytoplasm, and complex developmental program. Here we present evidence for programmed chang
Externí odkaz:
https://doaj.org/article/f149514e75c74f2bbf3460329a4df6ea
Autor:
Suzanne R, Lee, Daniel A, Pollard, Domenico F, Galati, Megan L, Kelly, Brian, Miller, Christina, Mong, Megan N, Morris, Kerry, Roberts-Nygren, Geoffrey M, Kapler, Matthew, Zinkgraf, Hung Q, Dang, Erica, Branham, Jason, Sasser, Erin, Tessier, Courtney, Yoshiyama, Maya, Matsumoto, Gaea, Turman
Publikováno v:
Molecular Biology of the Cell
Endogenous RNA interference (RNAi) pathways regulate a wide range of cellular processes in diverse eukaryotes, yet in the ciliated eukaryote, Tetrahymena thermophila, the cellular purpose of RNAi pathways that generate ∼23–24 nucleotide (nt) smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ab265a1c0020eeb2664ccb44c84046c
https://pubmed.ncbi.nlm.nih.gov/34010017
https://pubmed.ncbi.nlm.nih.gov/34010017
Autor:
Jun Wang, Courtney L. Baetge, Geoffrey M. Kapler, Jian Q. Feng, Qingguo Zhao, Michael A. Deveau, Bo Hai, Linying Zhang, Fei Liu
Publikováno v:
Cancer Res
Irreversible hypofunction of salivary glands is a common side effect of radiotherapy for head and neck cancer and is difficult to remedy. Recent studies indicate that transient activation of Hedgehog signaling rescues irradiation-impaired salivary fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ba136dcc56efebf05408cc2a5e0945
https://europepmc.org/articles/PMC7744395/
https://europepmc.org/articles/PMC7744395/