Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Geoffrey L Chupp"'
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2011 (2024)
This review provides an overview of evidence supporting the existence of distinct homeostatic and inflammatory eosinophil subpopulations in health and disease. Particular emphasis is placed on describing the phenotypic and functional roles of these e
Externí odkaz:
https://doaj.org/article/544a9190143b40879961abcf4bec7582
Autor:
Unnur S Bjornsdottir, Stephen T Holgate, Padmalatha S Reddy, Andrew A Hill, Charlotte M McKee, Cristina I Csimma, Amy A Weaver, Holly M Legault, Clayton G Small, Renee C Ramsey, Debra K Ellis, Conor M Burke, Philip J Thompson, Peter H Howarth, Andrew J Wardlaw, Phillip G Bardin, David I Bernstein, Louis B Irving, Geoffrey L Chupp, George W Bensch, Gregory W Bensch, Jon E Stahlman, Monroe Karetzky, James W Baker, Rachel L Miller, Brad H Goodman, Donald G Raible, Samuel J Goldman, Douglas K Miller, John L Ryan, Andrew J Dorner, Frederick W Immermann, Margot O'Toole
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21902 (2011)
Asthma exacerbations remain a major unmet clinical need. The difficulty in obtaining airway tissue and bronchoalveolar lavage samples during exacerbations has greatly hampered study of naturally occurring exacerbations. This study was conducted to de
Externí odkaz:
https://doaj.org/article/f4ed057e1067408a9023f1d201f1a2b4
iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects
Autor:
Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Single-cell RNA sequencing (scRNA-seq) technology has enabled assessment of transcriptome-wide changes at single-cell resolution. Due to the heterogeneity in environmental exposure and genetic background across subjects, subject e
Externí odkaz:
https://doaj.org/article/98bb000233a34cca8225fba23b3cf131
Autor:
Boyang Li, Yuxuan Wang, Zixiao Wang, Xinyue Li, Shannon Kay, Geoffrey L. Chupp, Hongyu Zhao, Jose L. Gomez
Publikováno v:
ERJ Open Research, Vol 9, Iss 4 (2023)
Rationale Asthma is a complex, heterogeneous disease strongly associated with type 2 inflammation, and blood eosinophil counts guide therapeutic interventions in moderate and severe asthma. Eosinophils are leukocytes involved in type 2 immune respons
Externí odkaz:
https://doaj.org/article/cf4dba32712a43009fff086a932b3f20
Autor:
Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/3da99a1637a2445db9e02f0e0409547c
Autor:
William J. Calhoun, Geoffrey L. Chupp
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 18, Iss 1, Pp 1-13 (2022)
Abstract Globally, a small proportion (5–12%) of asthma patients are estimated to have severe disease. However, severe asthma accounts for disproportionately high healthcare resource utilization. The Global Initiative for Asthma (GINA) management c
Externí odkaz:
https://doaj.org/article/4fbd6d8e6b9b4d6099d4142c57c8c64b
Autor:
Peter G. Gibson, Charlene M. Prazma, Geoffrey L. Chupp, Eric S. Bradford, Mark Forshag, Stephen A. Mallett, Steve W. Yancey, Steven G. Smith, Elisabeth H. Bel
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Comorbidities can complicate the management of severe asthma; therefore, the presence of comorbid conditions or traits often need to be considered when considering treatment options for patients with severe asthma. The aim of this
Externí odkaz:
https://doaj.org/article/4fe77ef5132740d89e33a7204d9137e6
Autor:
Ailu Chen, Maria P. Diaz-Soto, Miguel F. Sanmamed, Taylor Adams, Jonas C. Schupp, Amolika Gupta, Clemente Britto, Maor Sauler, Xiting Yan, Qing Liu, Gustavo Nino, Charles S. Dela Cruz, Geoffrey L. Chupp, Jose L. Gomez
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune res
Externí odkaz:
https://doaj.org/article/05c051abaec84697b39d9b4b3cb098cb
Autor:
Aaron Hakim, Isabel S. Bazan, Mamadou L. Sanogo, Edward P. Manning, Jeffrey S. Pollak, Geoffrey L. Chupp
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency disorder defined by high serum immunoglobulin E titers that is associated with recurrent respiratory infections, formation of pneumoatoceles, recurrent skin
Externí odkaz:
https://doaj.org/article/de038037dbaf4451af1109b0829d53ef
Autor:
Klaus F. Rabe, Ian D. Pavord, William W. Busse, Geoffrey L. Chupp, Kenji Izuhara, Arman Altincatal, Rebecca Gall, Nami Pandit‐Abid, Yamo Deniz, Paul J. Rowe, Juby A. Jacob‐Nara, Amr Radwan
Publikováno v:
Allergy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::446e76610fd76985cabc9050afd8ee56
https://doi.org/10.1111/all.15747
https://doi.org/10.1111/all.15747