Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Geoffrey Keir"'
Autor:
Jeremy Rees, S Griffin, Geoffrey Keir, Robin Wait, Paul M. Candler, Miles D. Chapman, AJ Church, Gavin Giovannoni, Russell C. Dale
Background: Adult opsoclonus-myoclonus (OM), a disorder of eye movements accompanied by myoclonus affecting the trunk, limbs, or head, is commonly associated with an underlying malignancy or precipitated by viral infection. Methods: We present the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8160a1801203321336268b334899df
https://ora.ox.ac.uk/objects/uuid:a5c25d7c-7fb0-473a-a830-98c215e40999
https://ora.ox.ac.uk/objects/uuid:a5c25d7c-7fb0-473a-a830-98c215e40999
Autor:
Geoffrey Keir, E J Thompson, Desmond Kidd, Gavin Giovannoni, DH Miller, Marc Feldmann, Brian Kendall, Alan J. Thompson, J W Thorpe, I. F. Moseley
OBJECTIVE: To determine whether concentrations of soluble E-selectin (sE-selectin), an immunological marker of endothelial activation, were correlated with gadolinium-DPTA enhancement on MRI in patients with multiple sclerosis. METHODS: Serial sE-sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd56d498e79b8d716588e6db1fa06f8
https://doi.org/10.1136/jnnp.60.1.20
https://doi.org/10.1136/jnnp.60.1.20
Publikováno v:
International Journal of Stroke. 7:454-459
Background and purpose It has previously been reported that serum levels of vascular endothelial growth factor are raised after acute ischemic stroke compared to healthy controls. The aim of this prospective study was to ascertain whether serum vascu
Autor:
Miles D. Chapman, Andrew Tarnaris, Geoffrey Keir, Ahmed K Toma, Axel Petzold, Laurence D Watkins, Neil Kitchen
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 80:1130-1133
Background: External lumbar drainage (ELD) is known as a good predictor of favourable outcome in shunting patients suffering from idiopathic normal pressure hydrocephalus (iNPH). Methods: Eleven patients suffering from iNPH had a lumbar drain (LD) in
Autor:
Axel Petzold, Hayrettin Tumani, Johannes Brettschneider, Atsushi Takeda, Yasuto Itoyama, N M F Murray, Geoffrey Keir, Mary M. Reilly, Kazutaka Jin, Nicholas Hirsch
Publikováno v:
Muscle & Nerve. 40:42-49
Early predictors of prognosis in Guillain-Barre syndrome (GBS) are needed to identify patients who are likely to make a poor recovery and to guide therapeutic decision-making in the acute phase. Here we investigate whether axonal protein biomarkers r
Autor:
Eduardo Tolosa, Olivier Rascol, Axel Petzold, Lars Rosengren, Nil Dizdar, Niall Quinn, Edward J. Thompson, Geoffrey Keir, Gregor K. Wenning, Björn Holmberg
Publikováno v:
Journal of the Neurological Sciences. 279:76-79
Background Two cerebrospinal fluid (CSF) biomarkers specific for neurodegeneration have recently emerged — the neurofilament light (NfL, 68 kDa) and heavy (NfH, 190–210 kDa) chains. This study investigated whether the CSF NfH and NfL levels or th
Publikováno v:
Cerebrovascular Diseases. 27:295-302
Background and Purpose: Serum S100B has been widely studied as a biomarker in acute ischaemic stroke. The main objective of this review was to appraise the published literature on S100B and determine its clinical applicability. Methods: Medline was s
Autor:
Chris H. Polman, Judith M. Eikelenboom, Bernard M. J. Uitdehaag, Geoffrey Keir, Serafina D’Urso, Antonio Belli, Barbara Tavazzi, Roberto Vagnozzi, Valentina Di Pietro, Gavin Giovannoni, Angela Maria Amorini, Axel Petzold, Giuseppe Lazzarino
Publikováno v:
Clinical Biochemistry, 42(10-11), 1001-1006. Elsevier Inc.
Amorini, A M, Petzold, A, Tavazzi, B, Eikelenboom, J, Keir, G, Belli, A, Giovannoni, G, Di Preto, V, Polman, C, D'Urso, S, Vagnozzi, R, Uitdehaag, B & Lazzarino, G 2009, ' Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients ', Clinical Biochemistry, vol. 42, no. 10-11, pp. 1001-1006 . https://doi.org/10.1016/j.clinbiochem.2009.03.020
Europe PubMed Central
Amorini, A M, Petzold, A, Tavazzi, B, Eikelenboom, J, Keir, G, Belli, A, Giovannoni, G, Di Preto, V, Polman, C, D'Urso, S, Vagnozzi, R, Uitdehaag, B & Lazzarino, G 2009, ' Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients ', Clinical Biochemistry, vol. 42, no. 10-11, pp. 1001-1006 . https://doi.org/10.1016/j.clinbiochem.2009.03.020
Europe PubMed Central
Objectives In this study, the concentrations of uric acid, purine profile and creatinine in samples of cerebrospinal fluid and serum of multiple sclerosis (MS) patients were measured by HPLC and compared with corresponding values recorded in patients
Autor:
Axel Petzold, Donna Grant, Djordje Gveric, Geoffrey Keir, M Groves, Klaus Schmierer, Miles D. Chapman, Louise Cuzner, Edward J. Thompson
Publikováno v:
Experimental Neurology
AimsAxonal pathology extends to the axonal cytoarchitecture leaving its signature on axoskeletal proteins. This study investigated whether neurofilament (NfH) phosphorylation would relate to the dynamics of axonal pathology in multiple sclerosis (MS)
Autor:
Stephen J. Wroe, JS Jackson, Klaus Schmierer, Durre Siddique, Geoffrey Keir, Daniel J. Tozer, Nick C. Fox, Mara Cercignani, Gerard R. Ridgway, David G. MacManus, John S. Thornton, Basil H. Ridha, Paul S. Tofts
Publikováno v:
Magnetic Resonance in Medicine. 59:190-195
There is increasing interest in imaging cadavers for noninvasive autopsies for research purposes. However, the temperature is well below that of in vivo imaging, and a variety of interesting 'cold brain' effects are observed. At lower temperatures co