Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Geoffrey J. Blackwell"'
Publikováno v:
Platelets, Vol 30, Iss 1, Pp 3-6 (2019)
In 1960, Gustav Born was appointed to head the Department of Pharmacology at the Royal College of Surgeons in London. The next 13 years would prove to be the most productive in his scientific career and the most important in the development of the De
Externí odkaz:
https://doaj.org/article/907d78d1c0ac4ff6a73b9566354774ca
Publikováno v:
Platelets. 30:3-6
In 1960, Gustav Born was appointed to head the Department of Pharmacology at the Royal College of Surgeons in London. The next 13 years would prove to be the most productive in his scientific career and the most important in the development of the De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a45810053a774ff3902a925f75408b
https://doi.org/10.1080/09537104.2018.1513252
https://doi.org/10.1080/09537104.2018.1513252
Autor:
Michael Yeadon, Caroline Craig, Peter John Wates, Simon Teanby Hodgson, Nigel Boughton-Smith, Geoffrey J. Blackwell
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:2565-2570
The achiral cyclobutyl group is an effective replacement for the chiral linking group required in hydroxyureas for good in vivo activity against 5-Lipoxygenase. The principle is illustrated in two achiral 5-LO inhibitors: 858C, a more potent inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb881aa591dc4366761cc9fb6198f49
https://doi.org/10.1016/s0960-894x(01)80717-4
https://doi.org/10.1016/s0960-894x(01)80717-4
Autor:
Caroline Craig, Michael Yeadon, Simon Teanby Hodgson, Nigel Boughton-Smith, Peter John Wates, Geoffrey J. Blackwell
Publikováno v:
ChemInform. 25
The achiral cyclobutyl group is an effective replacement for the chiral linking group required in hydroxyureas for good in vivo activity against 5-Lipoxygenase. The principle is illustrated in two achiral 5-LO inhibitors: 858C, a more potent inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e022c56fc4420e78b3c282b5e9a2c69
https://doi.org/10.1002/chin.199427097
https://doi.org/10.1002/chin.199427097
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 718:60-65
The functional viability of stored human platelets, washed in the presence and absence of prostacyclin, was examined over a 96 h period. Platelet counts, aggregation responses and cyclic AMP levels were monitored as well as the spontaneous generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e419969280f339255a29c890cd55176f
https://doi.org/10.1016/0304-4165(82)90009-5
https://doi.org/10.1016/0304-4165(82)90009-5
Publikováno v:
Thrombosis Research. 37:103-114
The effect of several vitamin K (Vit K) analogues on the aggregation of human platelets was examined. The analogues were potent inhibitors of aggregation induced by ADP, thrombin, collagen and arachidonate but were less active against aggregation ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba7a23e8c0d1eb9b9194e95cda342c2
https://doi.org/10.1016/0049-3848(85)90037-4
https://doi.org/10.1016/0049-3848(85)90037-4
Autor:
Geoffrey J. Blackwell
Publikováno v:
British journal of pharmacology. 79(2)
The secretion of the phospholipase A2-inhibitor macrocortin and the binding of dexamethasone were studied in suspensions of rat peritoneal macrophages. Corticosteroid-induced macrocortin secretion was specific for glucocorticoids and did not occur in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76afef887581c06a560b631aa24cb38
https://pubmed.ncbi.nlm.nih.gov/6317116
https://pubmed.ncbi.nlm.nih.gov/6317116