Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Geoffrey Gourinchas"'
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Akademický článek
Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor
Autor: Geoffrey Gourinchas, Udo Heintz, Andreas Winkler
Publikováno v: eLife, Vol 7 (2018)
Organisms adapt to environmental cues using diverse signaling networks. In order to sense and integrate light for regulating various biological functions, photoreceptor proteins have evolved in a modular way. This modularity is targeted in the develo
Externí odkaz: https://doaj.org/article/bd3cd1740be24e5d96421e7d527ac78b
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2
Characterisation of sequence–structure–function space in sensor–effector integrators of phytochrome-regulated diguanylate cyclases
Autor: Cornelia Böhm, Geoffrey Gourinchas, Sophie Zweytick, Elvira Hujdur, Martina Reiter, Sara Trstenjak, Christoph Wilhelm Sensen, Andreas Winkler
Publikováno v: Photochemical & Photobiological Sciences. 21:1761-1779
Understanding the relationship between protein sequence, structure and function is one of the fundamental challenges in biochemistry. A direct correlation, however, is often not trivial since protein dynamics also play an important functional role—
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb49795c4fc5bdbfe5bf988b4df84b88
https://doi.org/10.1007/s43630-022-00255-7
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3
Influence of the N-terminal segment and the PHY-tongue element on light-regulation in bacteriophytochromes
Autor: Andreas Winkler, Geoffrey Gourinchas, Ursula Vide
Publikováno v: The Journal of Biological Chemistry
Photoreceptors enable the integration of ambient light stimuli to trigger lifestyle adaptations via modulation of central metabolite levels involved in diverse regulatory processes. Red light–sensing bacteriophytochromes are attractive targets for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc208ff8bd960e2a11074216917d038
https://doi.org/10.1074/jbc.ra118.007260
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4
The PHY Domain Dimer Interface of Bacteriophytochromes Mediates Cross-talk between Photosensory Modules and Output Domains
Autor: Nikolina Todorovic, Marco Balasso, Cornelia Böhm, Andreas Winkler, Geoffrey Gourinchas
Publikováno v: Journal of molecular biology. 433(15)
Protein dynamics play a major role for the catalytic function of enzymes, the interaction of protein complexes or signal integration in regulatory proteins. In the context of multi-domain proteins involved in light-regulation of enzymatic effectors,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37c90d06a1c38ed819598c217216ec0
https://pubmed.ncbi.nlm.nih.gov/34116122
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5
Distinct chromophore-protein environments enable asymmetric activation of a bacteriophytochrome activated diguanylate cyclase
Autor: Geoffrey Gourinchas, Andreas Winkler, Peter Hildebrandt, David Buhrke, Melanie J. I. Müller, Norbert Michael
Publikováno v: JBC papers in press 295, 539-551 (2020). doi:10.1074/jbc.RA119.011915
'Journal of Biological Chemistry ', vol: 295, pages: 539-551 (2020)
The Journal of Biological Chemistry
Journal of Biological Chemistry
JBC papers in press 295, 539-551 (2020). doi:10.1074/jbc.RA119.011915
Sensing of red and far-red light by bacteriophytochromes involves intricate interactions between their bilin chromophore and the protein environment. The light-triggered rearr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62af068fca2c884229503e560bdaaa9c
https://bib-pubdb1.desy.de/record/429891
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6
Bacteriophytochromes - from informative model systems of phytochrome function to powerful tools in cell biology
Autor: Andreas Winkler, Stefan Etzl, Geoffrey Gourinchas
Publikováno v: Current opinion in structural biology. 57
Bacteriophytochromes are a subfamily of the diverse light responsive phytochrome photoreceptors. Considering their preferential interaction with biliverdin IXα as endogenous cofactor, they have recently been used for creating optogenetic tools and e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba483ef0099524945dbd34ec9f35027
https://pubmed.ncbi.nlm.nih.gov/30878713
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7
Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor
Autor: Udo Heintz, Andreas Winkler, Geoffrey Gourinchas
Publikováno v: eLife 7, e34815 (2018). doi:10.7554/eLife.34815
eLife, Vol 7 (2018)
'eLife ', vol: 7, pages: e34815-1-e34815-25 (2018)
Organisms adapt to environmental cues using diverse signaling networks. In order to sense and integrate light for regulating various biological functions, photoreceptor proteins have evolved in a modular way. This modularity is targeted in the develo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ee04760a38ef2054df52eea6e7dc32
https://doi.org/10.7554/elife.34815
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9
A synthetic biology approach for the transformation of l-α-amino acids to the corresponding enantiopure (R)- or (S)-α-hydroxy acids
Autor: Nina Richter, Wolfgang Kroutil, Eduardo Busto, Geoffrey Gourinchas, Birgit Wiltschi, Manuela Killinger
Publikováno v: Chemical communications (Cambridge, England). 51(14)
Combinatorial assembly and variation of promoters on a single expression plasmid allowed the balance of the catalytic steps of a three enzyme (l-AAD, HIC, FDH) cascade in E. coli. The designer cell catalyst quantitatively transformed l-amino acids to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30edec44a7c01b17863538ab7bb2d8f2
https://pubmed.ncbi.nlm.nih.gov/25574527
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