Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Geoffrey Fucile"'
Autor:
Badri Nath Dubey, Viktoriya Shyp, Geoffrey Fucile, Holger Sondermann, Urs Jenal, Tilman Schirmer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence. The recent identification of SmbA, an effector protein from
Externí odkaz:
https://doaj.org/article/a71121d7c6894d3787826e29a4304299
Autor:
Tuyana Boldanova, Geoffrey Fucile, Jan Vosshenrich, Aleksei Suslov, Caner Ercan, Mairene Coto-Llerena, Luigi M. Terracciano, Christoph J. Zech, Daniel T. Boll, Stefan Wieland, Markus H. Heim
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 11, Pp 100444- (2021)
Summary: Although transarterial chemoembolization (TACE) is the most widely used treatment for intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset of patients. In this study, we combine clinical, radiolog
Externí odkaz:
https://doaj.org/article/24d4d9cd9de347eb9e55f10515c24c82
Autor:
Baran Koç, Geoffrey Fucile, Roland Schmucki, Nicolas Giroud, Tobias Bergauer, Benjamin J. Hall
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Genome-wide sequencing technologies have greatly contributed to our understanding of the genetic basis of neurodevelopmental disorders such as autism spectrum disorder (ASD). Interestingly, a number of ASD-related genes express natural antisense tran
Externí odkaz:
https://doaj.org/article/18f7e11508cd4c069524ef4e893f170d
Autor:
Geoffrey Fucile, David Di Biase, Hardeep Nahal, Garon La, Shokoufeh Khodabandeh, Yani Chen, Kante Easley, Dinesh Christendat, Lawrence Kelley, Nicholas J Provart
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15237 (2011)
Visualization tools for biological data are often limited in their ability to interactively integrate data at multiple scales. These computational tools are also typically limited by two-dimensional displays and programmatic implementations that requ
Externí odkaz:
https://doaj.org/article/9b8e3dc32b5748bc8622706f1939309e
Publikováno v:
PLoS Genetics, Vol 4, Iss 12, p e1000292 (2008)
Shikimate kinase (SK; EC 2.7.1.71) catalyzes the fifth reaction of the shikimate pathway, which directs carbon from the central metabolism pool to a broad range of secondary metabolites involved in plant development, growth, and stress responses. In
Externí odkaz:
https://doaj.org/article/2829abbd65f74ffcb928253fe23c3649
Autor:
Jimmy Poulin, Nicholas J. Provart, Valerie M. Crowley, Daniel C. Johnson, Dea Shahinas, Michael Kanaris, Geoffrey Fucile, Dinesh Christendat
Publikováno v:
The Plant Journal. 109:789-803
The shikimate pathway plays a central role in the biosynthesis of aromatic amino acids and specialized metabolites in plants. The first enzyme, 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAHPS) serves as a key regulatory point for the path
Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence. The recent identification of SmbA, an effector protein from Caulobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a2553bf40b278ba0eab3f37a7e23d
https://doi.org/10.1101/2022.07.30.502141
https://doi.org/10.1101/2022.07.30.502141
Autor:
Jan Vosshenrich, Christoph J. Zech, Stefan Wieland, T. Boldanova, Daniel T. Boll, Tobias Heye, Markus H. Heim, Geoffrey Fucile
Publikováno v:
European Radiology
Objectives To investigate if nested multiparametric decision tree models based on tumor size and CT texture parameters from pre-therapeutic imaging can accurately predict hepatocellular carcinoma (HCC) lesion response to transcatheter arterial chemoe
Autor:
Tohnyui Ndinyanka Fabrice, Christelle Bianda, Haiyan Zhang, Rajesh Jayachandran, Julie Ruer-Laventie, Mayumi Mori, Despina Moshous, Geoffrey Fucile, Alexander Schmidt, Jean Pieters
Maintenance of cell population size is fundamental to the proper functioning of multicellular organisms. Here, we describe a cell-intrinsic cell density–sensing pathway that enabled T cells to reach and maintain an appropriate population size. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac5bf1910e40c412b050b83116416c3
https://edoc.unibas.ch/90570/
https://edoc.unibas.ch/90570/
Publikováno v:
Nature neuroscience
Nervous system function relies on complex assemblies of distinct neuronal cell types that have unique anatomical and functional properties instructed by molecular programs. Alternative splicing is a key mechanism for the expansion of molecular repert