Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Geoffrey Férir"'
Publikováno v:
Molecules, Vol 19, Iss 12, Pp 21085-21112 (2014)
The glycoproteins on the surfaces of enveloped viruses, such as HIV, can be considered as a unique target for antiviral therapy. Different carbohydrate-binding agents (CBAs) target specific glycans present on viral glycoproteins of enveloped viruses.
Externí odkaz:
https://doaj.org/article/50dfec6fe8f7435cb95f38ce029b44ec
Autor:
Stephanie Gordts, Leentje Persoons, Sandra Claes, Geoffrey Férir, Mark Brönstrup, Roderich D. Süssmuth, Dominique Schols
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss , Pp 26- (2016)
Externí odkaz:
https://doaj.org/article/0b70bc79ead244bea3808c2ad2875163
Publikováno v:
Viruses, Vol 2, Iss 6, Pp 1279-1305 (2010)
While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lam
Externí odkaz:
https://doaj.org/article/a6498fc1b8444932a19b633d00c8433f
Autor:
Stephanie C Gordts, Geoffrey Férir, Thomas D'huys, Mariya I Petrova, Sarah Lebeer, Robert Snoeck, Graciela Andrei, Dominique Schols
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131219 (2015)
Lignosulfonic acid (LA), a low-cost lignin-derived polyanionic macromolecule, was extensively studied for its anti-HIV and anti-HSV activity in various cellular assays, its mechanism of viral inhibition and safety profile as potential microbicide.LA
Externí odkaz:
https://doaj.org/article/ce8f84e00ba644889d1abd56c8f3b64d
Autor:
Geoffrey Férir, Mariya I Petrova, Graciela Andrei, Dana Huskens, Bart Hoorelbeke, Robert Snoeck, Jos Vanderleyden, Jan Balzarini, Stefan Bartoschek, Mark Brönstrup, Roderich D Süssmuth, Dominique Schols
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64010 (2013)
Lantibiotics are peptides, produced by bacteria, that contain the noncanonical amino acid lanthionine and many of them exhibit antibacterial activities. The labyrinthopeptin A1 (LabyA1) is a prototype peptide of a novel class of carbacyclic lantibiot
Externí odkaz:
https://doaj.org/article/872bea6f6dfd45b8b8ca202f5c18c5d9
Autor:
Sam Noppen, Dominique Schols, Leonardus M. I. Koharudin, Geoffrey Férir, Dana Huskens, Angela M. Gronenborn
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:2746-2758
OBJECTIVES Oscillatoria agardhii agglutinin homologue (OAAH) proteins belong to a recently discovered lectin family. The founding member OAA and a designed hybrid OAAH (OPA) recognize similar but unique carbohydrate structures of Man-9, compared with
Autor:
Geoffrey Férir, David M. Markovitz, Jan Balzarini, Dominique Schols, Daniel M. Boudreaux, Dana Huskens, Michael D. Swanson, Kenneth E. Palmer
Publikováno v:
AIDS Research and Human Retroviruses; Vol 28
Carbohydrate-binding agents (CBAs) are potential HIV microbicidal agents with a high genetic barrier to resistance. We wanted to evaluate whether two mannose-specific CBAs, recognizing multiple and often distinct glycan structures on the HIV envelope
Autor:
Sandra Claes, Geoffrey Férir, Stephanie Gordts, Dominique Schols, Leentje Persoons, Roderich D. Süssmuth, Mark Brönstrup
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss, Pp 26-(2016)
Autor:
Roderich D. Süssmuth, Anne Hänchen, Dominique Schols, Katrien O. François, Frank Dettner, Dana Huskens, Bart Hoorelbeke, Geoffrey Férir
Publikováno v:
Virology; Vol 433
Feglymycin (FGM), a natural Streptomyces-derived 13mer peptide, consistently inhibits HIV replication in the lower μM range. FGM also inhibits HIV cell-to-cell transfer between HIV-infected T cells and uninfected CD4(+) T cells and the DC-SIGN-media
Publikováno v:
Virology. 417:253-258
Griffithsin (GRFT) is possibly the most potent anti-HIV peptide found in natural sources. Due to its potent and broad-spectrum antiviral activity and unique safety profile it has great potential as topical microbicide component. Here, we evaluated va