Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Geoffrey E. Purdum"'
Autor:
Cong Bi, James Chadwick, Merrill L. Davies, Albert J. DelMonte, Peng Geng, Andrew W. Glace, Rebecca A. Green, John A. Gurak, Matthew W. Haley, Brian L. He, Bahar Inankur, Christopher R. Jamison, Candice L. Joe, Sergei Kolotuchin, Dong Lin, Sha Lou, Jeffrey Nye, Adrian Ortiz, Geoffrey E. Purdum, Victor W. Rosso, Mansi Shah, Eric M. Simmons, Jason M. Stevens, Neil A. Strotman, Yichen Tan, Ling Zhang
Publikováno v:
The Journal of organic chemistry.
The development of a convergent route to the NLRP3 (nucleotide-binding domain and leucine-rich repeat-containing protein 3) agonist BMS-986299 is reported. The synthesis relies on a key Miyaura borylation and a tandem Suzuki-Miyaura coupling between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f146eddbd33628f75341b1e8fea485f
https://pubmed.ncbi.nlm.nih.gov/36516991
https://pubmed.ncbi.nlm.nih.gov/36516991
Autor:
Hua Chia Tai, Ye Zhu, Sloan Ayers, Guanghui Zhu, Martin D. Eastgate, Bin Zheng, Ben Cohen, Miao Yu, Geoffrey E. Purdum, Chao Hang, Hyunsoo Park, Michael A. Schmidt, Adam Joseph Freitag, James Paulson, Siwei Guo, Changxia Yuan, Melda Sezen-Edmonds, Weiqing Fu, Rogers Amanda J, Jonathan G. Shackman, Jason Zhu, Ben Hritzko, Brian Lingfeng He, Daniel S. Treitler, Qinggang Wang
Publikováno v:
The Journal of Organic Chemistry. 87:1934-1940
A highly stereoselective synthesis of a cyclic dinucleotide (CDN) STING agonist containing two chiral thiophosphoramidate linkages is described. These rare, yet key functional groups were, for the first time, installed efficiently and with high diast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f136684d522755cd8834b7b630c19b
https://doi.org/10.1021/acs.joc.1c01055
https://doi.org/10.1021/acs.joc.1c01055
Autor:
Carolyn S. Higman, Adrian Ortiz, Geoffrey E. Purdum, Ronald Carrasquillo-Flores, Yichen Tan, Kolotuchin Sergei, Steven R. Wisniewski, Thomas C. Malig, Jason E. Hein
Publikováno v:
Reaction Chemistry & Engineering. 5:1421-1428
We have developed a convenient two-step, one-pot method for the facile synthesis of cyanoimidazoles. By integrating a suite of reaction-monitoring techniques, we were able to interrogate each transformation independently. We observed that formation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0df44b6e491e1e6af685ac88f720cf4
https://doi.org/10.1039/d0re00234h
https://doi.org/10.1039/d0re00234h
Autor:
Ryan D. Pensack, Geoffrey E. Purdum, Samuel M. Mazza, Christopher Grieco, John B. Asbury, John E. Anthony, Yueh-Lin Loo, Gregory D. Scholes
Publikováno v:
The journal of physical chemistry. C, Nanomaterials and interfaces. 126(23)
Singlet fission is a process in conjugated organic materials that has the potential to considerably improve the performance of devices in many applications, including solar energy conversion. In any application involving singlet fission, efficient tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784cec0abbd4b40925081f2649f35d6a
https://pubmed.ncbi.nlm.nih.gov/35756579
https://pubmed.ncbi.nlm.nih.gov/35756579
Solvent–Molecule Interactions Govern Crystal-Habit Selection in Naphthalene Tetracarboxylic Diimides
Autor:
Chad Risko, Thomas Gessner, Yueh-Lin Loo, Nicholas Telesz, Geoffrey E. Purdum, Sean M. Ryno, Paulette Clancy, R. Thomas Weitz, Xiangyu Chen, Nikita Sengar
Publikováno v:
Chemistry of Materials. 31:9691-9698
Controlling hierarchical structural development in organic semiconductors, and across synthetic materials more broadly, is critical to the performance of the material in device applications. Such r...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a2ed0d5c69f7f99746de0fc465c7b4
https://doi.org/10.1021/acs.chemmater.9b03142
https://doi.org/10.1021/acs.chemmater.9b03142
Autor:
Qianxiang Ai, Oana D. Jurchescu, Chad Risko, Geoffrey E. Purdum, Anthony J. Petty, Devin B. Granger, Yueh-Lin Loo, Sean Parkin, John E. Anthony, Alex M. Boehm, Kaichen Gu, Kenneth R. Graham, Jeni C. Sorli, Hamna F. Haneef, C. P. L. Rubinger
Publikováno v:
Chemical Science. 10:10543-10549
Herein, we describe the design and synthesis of a suite of molecules based on a benzodithiophene “universal crystal engineering core”. After computationally screening derivatives, a trialkylsilylethyne-based crystal engineering strategy was emplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e0f34bb8f701baf0195ad3a279ce9ac
https://doi.org/10.1039/c9sc02930c
https://doi.org/10.1039/c9sc02930c
Autor:
David J. Rios, Theodore A. Tyler, Gabriel S. Jackson, Jonathan S. Alexander, Judith L. Palmer Castor, Alireza Minagar, Geoffrey E. Purdum, Trevor Percival Castor, Maria I. Vizcanio, Ping Yi, Kasey Jackson, Lisa Schrott, J. Winny Yun, Christopher Webb
Publikováno v:
Current Alzheimer research. 17(14)
Background: Alzheimer’s disease (AD) animal models have revealed neuroprotective actions of Bryostatin-1 mediated by activation of novel PKC isoforms, suppression of beta-amyloid and downregulation of inflammatory and angiogenic events, making Bryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de75c504f17c7701010b266d00009220
https://pubmed.ncbi.nlm.nih.gov/33602091
https://pubmed.ncbi.nlm.nih.gov/33602091
Autor:
Chen-Xia Hu, Geoffrey E. Purdum, Zi-Fa Shi, Chun-Lin Sun, Zhi-Ping Fan, Xiang-Yang Li, Xiangfeng Shao, Hao-Li Zhang, Yueh-Lin Loo, Xian Fei
Publikováno v:
Chemistry of Materials. 30:3638-3642
Thermal instability is one of the major obstacles for the application of organic devices. We report herein for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c40b771c7a04b2abe58fbffa72d4c30
https://doi.org/10.1021/acs.chemmater.8b01579
https://doi.org/10.1021/acs.chemmater.8b01579
Autor:
Christopher Grieco, Dwight S. Seferos, Andrew J. Tilley, Grayson S. Doucette, Ryan D. Pensack, Yueh-Lin Loo, John B. Asbury, Daniel G. Oblinsky, Jacob C. Dean, Devin B. Granger, Geoffrey E. Purdum, Evgeny E. Ostroumov, Gregory D. Scholes, John E. Anthony
Publikováno v:
Chemical Science. 9:6240-6259
Singlet fission is a process that splits collective excitations, or excitons, into two with unity efficiency. This exciton splitting process, unique to molecular photophysics, has the potential to considerably improve the efficiency of optoelectronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b940d83a268de349f0eea2666542000b
https://doi.org/10.1039/c8sc00293b
https://doi.org/10.1039/c8sc00293b
Autor:
John B. Asbury, Samuel M. Mazza, Andrew J. Tilley, Evgeny E. Ostroumov, Gregory D. Scholes, Ryan D. Pensack, Geoffrey E. Purdum, Christopher Grieco, Yueh-Lin Loo, John E. Anthony, Dwight S. Seferos
Publikováno v:
Materials Horizons. 4:915-923
Amorphous nanoparticles of the singlet fission chromophore 6,13-bis(triisopropylsilylethynyl)pentacene (TIPS-Pn) are fully crystallized through co-precipitation with a chemical additive. Time-resolved measurements indicate that singlet fission in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ac2e94cac16adba3e961932917fae2
https://doi.org/10.1039/c7mh00303j
https://doi.org/10.1039/c7mh00303j