Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Geoffrey E Packe"'
Autor:
Anna K Coussens, Robert J Wilkinson, Vladyslav Nikolayevskyy, Paul T Elkington, Yasmeen Hanifa, Kamrul Islam, Peter M Timms, Graham H Bothamley, Alleyna P Claxton, Geoffrey E Packe, Mathina Darmalingam, Robert N Davidson, Heather J Milburn, Lucy V Baker, Richard D Barker, Francis A Drobniewski, Charles A Mein, Leena Bhaw-Rosun, Rosamond A Nuamah, Christopher J Griffiths, Adrian R Martineau
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003468 (2013)
Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine secretion when cultured with human macrophages in vitro. Circulating
Externí odkaz:
https://doaj.org/article/4a0183781eb747bc9c277014a7644535
Autor:
Adrian R. Martineau, Robert J. Wilkinson, Chris Griffiths, David M. Lowe, Geoffrey E. Packe, Asela Bandara, Richard D. Barker
Publikováno v:
European Respiratory Journal. 42:1752-1757
To the Editor: Experimental animal work indicates that neutrophils play a key role in the immune response to mycobacteria [1, 2]. They appear protective against early infection [3] but in established disease, neutrophilia associates with pathology [1
Autor:
Robert J. Wilkinson, Beate Kampmann, Geoffrey E. Packe, Robert N. Davidson, Sandra J. Rainbow, Sandra Eldridge, Chris Griffiths, Sandra M. Newton, Zoë J. Maunsell, Adrian R. Martineau, Jacqueline L. Berry, Katalin A. Wilkinson, Bridget M. Hall
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 176:208-213
Vitamin D was used to treat tuberculosis (TB) in the preantibiotic era. Prospective studies to evaluate the effect of vitamin D supplementation on antimycobacterial immunity have not previously been performed.To determine the effect of vitamin D supp
Autor:
Beate Kampmann, Robert J. Wilkinson, Geoffrey E. Packe, Adrian R. Martineau, Katalin A. Wilkinson, Niga Nawroly, Chris Griffiths, Bridget M. Hall, Sandra M. Newton, Robert N. Davidson
Publikováno v:
Journal of Clinical Investigation. 117:1988-1994
Neutrophils contain antimicrobial peptides with antituberculous activity, but their contribution to immune resistance to tuberculosis (TB) infection has not been previously investigated to our knowledge. We determined differential white cell counts i
Autor:
Geoffrey E Packe, Tanuj S Lad
Publikováno v:
Emergency medicine journal : EMJ. 31(11)
Introduction The incidence of tuberculosis (TB) has increased over the last two decades. Many patients with TB preferentially access healthcare via the emergency department (ED) prediagnosis, presenting an early opportunity for diagnosis. Methods We
Autor:
Robert N. Davidson, Rosamond A. Nuamah, Chris Griffiths, Adrian R. Martineau, Douglas B. Young, Heather Milburn, Leena Bhaw-Rosun, Peter Timms, Anna K. Coussens, Geoffrey E. Packe, Francis Drobniewski, Timothy R Venton, L V Baker, Graham H. Bothamley, Robert J. Wilkinson, Mathina Darmalingam, Vladyslav Nikolayevskyy, Yasmeen Hanifa, Paul T. Elkington, Charles A. Mein, Kamrul Islam, Richard D. Barker
Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol concentrations, and thus has a potential role in the prevention and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc1dd8dc85ad1af791d08c6623b4d9e
http://hdl.handle.net/10044/1/10257
http://hdl.handle.net/10044/1/10257
Autor:
Chris Griffiths, Robert N. Davidson, Bridget M. Hall, Sandra M. Newton, Geoffrey E. Packe, Beate Kampmann, Robert J. Wilkinson, Adrian R. Martineau, Katalin A. Wilkinson
Publikováno v:
Journal of Infection. 56:301-302
Autor:
Geoffrey E. Packe, Sandra M. Newton, Beate Kampmann, S J Rainbow, Chris Griffiths, Zoë J. Maunsell, Adrian R. Martineau, Katalin A. Wilkinson, B.M. Hall, Robert N. Davidson, Robert J. Wilkinson, Sandra Eldridge
Publikováno v:
Journal of Infection. 54:e189
Publikováno v:
Oncology. 42:44-47
A patient with alcoholic liver cirrhosis, diabetes mellitus and porphyria cutanea tarda (PCT) is described, who subsequently died of hepatocellular carcinoma. The literature relating PCT to the incidence of primary hepatoma is reviewed, and the mecha