Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geoffrey D. Clapp"'
Autor:
Doron Levy, Franck E. Nicolini, Hélène Labussière-Wallet, Jérémy Ruby, Samuel Bernard, Raouf El Cheikh, Thomas Lepoutre, Geoffrey D. Clapp
Table S1:Universal parameters estimates. Table S2: Patient-specific parameter estimates. Figure S1: Comparison of the model with and without an autologous immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059c82a90a73f3b1d273b05c7d329e8a
https://doi.org/10.1158/0008-5472.22407660
https://doi.org/10.1158/0008-5472.22407660
Autor:
Doron Levy, Franck E. Nicolini, Hélène Labussière-Wallet, Jérémy Ruby, Samuel Bernard, Raouf El Cheikh, Thomas Lepoutre, Geoffrey D. Clapp
Imatinib and other tyrosine kinase inhibitors (TKI) have improved treatment of chronic myelogenous leukemia (CML); however, most patients are not cured. Deeper mechanistic understanding may improve TKI combination therapies to better control the resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c27bf527d0a2c1957063530e927f79
https://doi.org/10.1158/0008-5472.c.6507360
https://doi.org/10.1158/0008-5472.c.6507360
Autor:
Apollos Besse, Franck E. Nicolini, Doron Levy, Geoffrey D. Clapp, Thomas Lepoutre, Samuel Bernard
Publikováno v:
Bulletin of Mathematical Biology
Bulletin of Mathematical Biology, 2017, pp.1-27. ⟨10.1007/s11538-017-0272-7⟩
Bulletin of Mathematical Biology, Springer Verlag, 2017, pp.1-27. ⟨10.1007/s11538-017-0272-7⟩
Bulletin of Mathematical Biology, 2017, pp.1-27. ⟨10.1007/s11538-017-0272-7⟩
Bulletin of Mathematical Biology, Springer Verlag, 2017, pp.1-27. ⟨10.1007/s11538-017-0272-7⟩
International audience; We describe here a simple model for the interaction between leukemic cells and the autologous immune response in chronic phase chronic myelogenous leukemia (CML). This model is a simplified version of the model we proposed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff40a99adbf2db5b7e0a6e68ed47f0b2
https://pubmed.ncbi.nlm.nih.gov/28536994
https://pubmed.ncbi.nlm.nih.gov/28536994
Publikováno v:
Journal of Mathematical Neuroscience
Sensory input to the lamprey central pattern generator (CPG) for locomotion is known to have a significant role in modulating lamprey swimming. Lamprey CPGs are known to have the ability to entrain to a bending stimulus, that is, in the presence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae229114982643c37ba390a8b0c8560c
https://doi.org/10.1186/s13408-016-0038-9
https://doi.org/10.1186/s13408-016-0038-9
Autor:
Samuel Bernard, Doron Levy, Thomas Lepoutre, Raouf El Cheikh, Jeremy Ruby, Geoffrey D. Clapp, Hélène Labussière-Wallet, Franck E. Nicolini
Publikováno v:
Cancer Research
Cancer Research, 2015, 75 (19), pp.4053-62. ⟨10.1158/0008-5472.CAN-15-0611⟩
Cancer Research, American Association for Cancer Research, 2015, 75 (19), pp.4053-62. ⟨10.1158/0008-5472.CAN-15-0611⟩
Cancer Research, 2015, 75 (19), pp.4053-62. ⟨10.1158/0008-5472.CAN-15-0611⟩
Cancer Research, American Association for Cancer Research, 2015, 75 (19), pp.4053-62. ⟨10.1158/0008-5472.CAN-15-0611⟩
Imatinib and other tyrosine kinase inhibitors (TKI) have improved treatment of chronic myelogenous leukemia (CML); however, most patients are not cured. Deeper mechanistic understanding may improve TKI combination therapies to better control the resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363973829d314113aecded52124ab193
https://pubmed.ncbi.nlm.nih.gov/26359456
https://pubmed.ncbi.nlm.nih.gov/26359456
Autor:
Doron Levy, Geoffrey D. Clapp
Recently, there has been significant activity in the mathematical community, aimed at developing quantitative tools for studying leukemia and lymphoma. Mathematical models have been applied to evaluate existing therapies and to suggest novel therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2309277bb669c424144f041615f7487
https://europepmc.org/articles/PMC4698906/
https://europepmc.org/articles/PMC4698906/
Autor:
Geoffrey D. Clapp, Doron Levy
Publikováno v:
Mathematical Models of Tumor-Immune System Dynamics ISBN: 9781493917921
In this chapter we propose several modifications to the Roeder model of chronic myeloid leukemia (Roeder et al.: Nat. Med. 12(10), 1181–1184 2006). Specifically, we incorporate asymmetric division of stem cells and precursors, allow precursors to l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ea5d25a926a048ad0b10485d7e2177b
https://doi.org/10.1007/978-1-4939-1793-8_1
https://doi.org/10.1007/978-1-4939-1793-8_1
Publikováno v:
OncoImmunology. 5:e1122159
Many chronic myelogenous leukemia (CML) patients in chronic phase who respond well to imatinib therapy show fluctuations in their leukemic loads in the long-term. We developed a mathematical model of CML that incorporates the intervention of an autol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f878a2429a91a4c3a01dac5c0fe33e5e
https://doi.org/10.1080/2162402x.2015.1122159
https://doi.org/10.1080/2162402x.2015.1122159