Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Geoffrey D. Cassell"'
Autor:
Kefei Yu, Noritaka Adachi, Zarir E Karanjawala, Chih-Lin Hsieh, Darryl Shibata, Ryan A. Irvine, Michael R. Lieber, Geoffrey D. Cassell
Publikováno v:
Molecular and Cellular Biology. 25:294-302
Endonuclease G (endo G) is one of the most abundant nucleases in eukaryotic cells. It is encoded in the nucleus and imported to the mitochondrial intermembrane space. This nuclease is active on single- and double-stranded DNA. We genetically disrupte
Publikováno v:
Journal of Molecular Biology. 299:1203-1216
Molecular Biology ProgramSloan-Kettering Institute, NewYork, NY 10021, USAThe study of biochemical pathways requires the isolation and characteriz-ation of each and every intermediate in the pathway. For the site-specificrecombination reactions cata
Autor:
Stacy D. Carrington-Lawrence, Matthew D. Weitzman, Peter Ward, Thomas Melendy, Robert K. Hamatake, Bas van Breukelen, Sandra K. Weller, Peter C. van der Vliet, Travis H. Stracker, Yueh Ming Loo, Geoffrey D. Cassell
Publikováno v:
Journal of virology. 78(1)
Adeno-associated virus (AAV) type 2 is a human parvovirus whose replication is dependent upon cellular proteins as well as functions supplied by helper viruses. The minimal herpes simplex virus type 1 (HSV-1) proteins that support AAV replication in
Autor:
Geoffrey D. Cassell, Anca M. Segall
Publikováno v:
Journal of molecular biology. 327(2)
Holliday junctions are central intermediates in site-specific recombination reactions mediated by tyrosine recombinases. Because these intermediates are extremely transient, only artificially assembled Holliday junctions have been available for study
Publikováno v:
Journal of molecular biology. 299(5)
A wide variety of tools have been used to dissect biochemical pathways, inhibitors being chief among them. Combinatorial approaches have made the search for inhibitors much more efficient. We have applied such an approach to identify hexapeptides whi
Publikováno v:
Nucleic acids research. 27(4)
Bacteriophage lambda uses site-specific recombination to move its DNA into and out of the Escherichia coli genome. The recombination event is mediated by the phage-encoded integrase (Int) at short DNA sequences known as attachment ( att ) sites. Int
Publikováno v:
Virology. (2):206-214
Adeno-associated virus (AAV) replicates in the nucleus of infected cells, and therefore multiple nuclear import events are required for productive infection. We analyzed nuclear import of the viral Rep proteins and characterized a nuclear localizatio