Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Geoffrey D Young"'
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63303e1e95df28f9c3ec11824d417863
https://doi.org/10.1158/1078-0432.22457678
https://doi.org/10.1158/1078-0432.22457678
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary Table S4: DAVID clustering of 1660 Illumina probes up-regulated at least 2-fold in PD-L1+ melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d20ea9320f7573c2c11ebbbfac0a2b
https://doi.org/10.1158/1078-0432.22457681.v1
https://doi.org/10.1158/1078-0432.22457681.v1
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary Table S1, Supplementary Table S3, Supplementary Table S5. Supplementary Table S1: Genes selected for multiplex qRT-PCR array Supplementary Table S3: Functionally annotated gene categories from DAVID analysis of whole genome microarray r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6a23c46c1a5ae356405d59aff0ec2e
https://doi.org/10.1158/1078-0432.22457687
https://doi.org/10.1158/1078-0432.22457687
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary Table S2: 1660 Illumina probes up-regulated at least 2-fold in PD-L1+ melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2573cf2e3188838a12384c1a4d15ca5e
https://doi.org/10.1158/1078-0432.22457684
https://doi.org/10.1158/1078-0432.22457684
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Purpose: Blocking the immunosuppressive PD-1/PD-L1 pathway has antitumor activity in multiple cancer types, and PD-L1 expression on tumor cells and infiltrating myeloid cells correlates with the likelihood of response. We previously found that IFNG (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316e003722533f722ee8a6d7e8e03a40
https://doi.org/10.1158/1078-0432.c.6523649
https://doi.org/10.1158/1078-0432.c.6523649
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Figure S1, Figure S2, Figure S3. Supplementary Figure S1: Overlay of PD-L1 and LAG-3 IHC demonstrates close geographic association of these cell-surface markers in a melanoma lymph node metastasis. Supplementary Figure S2: Comparison of immunohistoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551529e7b32a5bdd888d729f73795b33
https://doi.org/10.1158/1078-0432.22457690
https://doi.org/10.1158/1078-0432.22457690
Autor:
Sara I. Pai, Drew M. Pardoll, Suzanne L. Topalian, Charles G. Drake, Lieping Chen, Justin A. Bishop, Hao Wang, Jeremy D. Richmon, Tullia C. Bruno, Belinda Akpeng, William H. Westra, Janis M. Taube, Geoffrey D. Young, Shiwen Peng, Sofia Lyford-Pike
PDF file - 28K, PD-1 expressing CD8+ T cells in non-cancerous tonsil tissue are able to produce IFN-g after stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c31678d1d978d8ee740e5c3a6dcf60
https://doi.org/10.1158/0008-5472.22397145.v1
https://doi.org/10.1158/0008-5472.22397145.v1
Autor:
Sara I. Pai, Drew M. Pardoll, Suzanne L. Topalian, Charles G. Drake, Lieping Chen, Justin A. Bishop, Hao Wang, Jeremy D. Richmon, Tullia C. Bruno, Belinda Akpeng, William H. Westra, Janis M. Taube, Geoffrey D. Young, Shiwen Peng, Sofia Lyford-Pike
XLSX file - 9K, IFN-g production from PD-1(+) and (-) TILs isolated from PD-L1 (+) and (-) HPV-HNSCCs; data corresponding to Figure 6B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37278a81e70cfc763b255d304dd4e51
https://doi.org/10.1158/0008-5472.22397142
https://doi.org/10.1158/0008-5472.22397142
Autor:
Sara I. Pai, Drew M. Pardoll, Suzanne L. Topalian, Charles G. Drake, Lieping Chen, Justin A. Bishop, Hao Wang, Jeremy D. Richmon, Tullia C. Bruno, Belinda Akpeng, William H. Westra, Janis M. Taube, Geoffrey D. Young, Shiwen Peng, Sofia Lyford-Pike
PDF file - 36K, Detection of PTEN by western blot and PD-L1 expression by flow cytometry in HPV(-) head and neck cancer lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2417303b958a8fcc708a901e18b91a48
https://doi.org/10.1158/0008-5472.22397148
https://doi.org/10.1158/0008-5472.22397148
Autor:
Justin A. Bishop, William C. Faquin, Thomas J. Diefenbach, Yang Cheng, Darawan Rinchai, Austin Mattox, Jessica Roelands, Talia M. Saal, William H. Westra, Wouter Hendrickx, Mikael J. Pittet, Davide Bedognetti, Sara I. Pai, Alan E. Berger, Francesco M. Marincola, Geoffrey D. Young
Publikováno v:
Am J Pathol
Viruses are the second leading cause of cancer worldwide, and human papillomavirus (HPV)-associated head and neck cancers are increasing in incidence in the United States. HPV preferentially infects the crypts of the tonsils rather than the surface e