Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Geoffrey Canet"'
Autor:
Geoffrey Canet, Maud Gratuze, Charleine Zussy, Mohamed Lala Bouali, Sofia Diego Diaz, Emma Rocaboy, Francis Laliberté, Noura B. El Khoury, Cyntia Tremblay, Françoise Morin, Frédéric Calon, Sébastien S. Hébert, Carl Julien, Emmanuel Planel
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106526- (2024)
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease with a complex origin, thought to involve a combination of genetic, biological and environmental factors. Insulin dysfunction has emerged as a potential factor contributing to AD
Externí odkaz:
https://doaj.org/article/dcd4305d1f464bebb1cac5efbabd5f46
Autor:
Behnaz Nateghi, Remi Keraudren, Gabriel Boulay, Marc Bazin, Claudia Goupil, Geoffrey Canet, Andréanne Loiselle, Isabelle St-Amour, Emmanuel Planel, Denis Soulet, Sébastien S. Hébert
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Huntington’s disease (HD) is a rare genetic neurodegenerative disorder caused by an expansion of CAG repeats in the Huntingtin (HTT) gene. One hypothesis suggests that the mutant HTT gene contributes to HD neuropathology through transcriptional dys
Externí odkaz:
https://doaj.org/article/4dba236033e24d1196f444a302dfe26c
Autor:
Charleine Zussy, Rijo John, Théo Urgin, Léa Otaegui, Claire Vigor, Niyazi Acar, Geoffrey Canet, Mathieu Vitalis, Françoise Morin, Emmanuel Planel, Camille Oger, Thierry Durand, Shinde L. Rajshree, Laurent Givalois, Padma V. Devarajan, Catherine Desrumaux
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 838 (2022)
Polyunsaturated fatty acids (PUFAs) are a class of fatty acids that are closely associated with the development and function of the brain. The most abundant PUFA is docosahexaenoic acid (DHA, 22:6 n-3). In humans, low plasmatic concentrations of DHA
Externí odkaz:
https://doaj.org/article/308438b8e5884c3fac96cf4b86c265a0
Autor:
Geoffrey Canet, Célia Hernandez, Charleine Zussy, Nathalie Chevallier, Catherine Desrumaux, Laurent Givalois
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that has important health and economic impacts in the elderly. Despite a better understanding of the molecular mechanisms leading to the appearance of major pathological hallmarks
Externí odkaz:
https://doaj.org/article/374a115fecc04f57aaa4296f36aefadc
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Alzheimer’s disease (AD) is the principal neurodegenerative pathology in the world displaying negative impacts on both the health and social ability of patients and inducing considerable economic costs. In the case of sporadic forms of AD (more tha
Externí odkaz:
https://doaj.org/article/bcd543d56b1b4bee91766e2e43fa8542
Autor:
Geoffrey Canet, Chloé Dias, Audrey Gabelle, Yannick Simonin, Fabien Gosselet, Nicola Marchi, Alain Makinson, Edouard Tuaillon, Philippe Van de Perre, Laurent Givalois, Sara Salinas
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Environmental factors such as chemicals, stress and pathogens are now widely believed to play important roles in the onset of some brain diseases, as they are associated with neuronal impairment and acute or chronic inflammation. Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/9fa479a2c89c45b6b56bbe3857703357
Autor:
Isabelle Guisle, Geoffrey Canet, Séréna Pétry, Parissa Fereydouni-Forouzandeh, Françoise Morin, Rémi Kérauden, Robert A. Whittington, Frédéric Calon, Sébastien S. Hébert, Emmanuel Planel
Publikováno v:
Neurobiology of Aging. 113:118-130
In Alzheimer's disease (AD), hyper-phosphorylation and aggregation of tau correlate with clinical progression and represent a valid therapeutic target. A recent 20-year prospective study revealed an association between moderate to high frequency of F
Autor:
Geoffrey Canet, Charleine Zussy, Célia Hernandez, Tangui Maurice, Catherine Desrumaux, Laurent Givalois
Publikováno v:
Pharmacology & Therapeutics. 245:108398
Autor:
Geoffrey Canet, Emma Zub, Charleine Zussy, Célia Hernandez, Marine Blaquiere, Valentin Garcia, Mathieu Vitalis, Frederic deBock, Maria Moreno‐Montano, Etienne Audinat, Catherine Desrumaux, Emmanuel Planel, Laurent Givalois, Nicola Marchi
Publikováno v:
Epilepsia
Epilepsia, 2022, 63 (4), pp.919-935. ⟨10.1111/epi.17186⟩
Epilepsia, 2022, 63 (4), pp.919-935. ⟨10.1111/epi.17186⟩
International audience; Objective: Although epilepsies and neurodegenerative disorders show pathophysiological similarities, their direct functional associations are unclear. Here, we tested the hypothesis that experimental seizures can induce tau hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c698cb331733ea3b7f378554c06d1
https://hal.science/hal-03594983
https://hal.science/hal-03594983
Autor:
Geoffrey Canet, Charleine Zussy, Célia Hernandez, Nathalie Chevallier, Nicola Marchi, Catherine Desrumaux, Laurent Givalois
Publikováno v:
Neuroendocrinology. 112(10)
Introduction: Among the risk factors identified in the sporadic forms of Alzheimer’s disease (AD), environmental and lifestyle elements are of growing interest. Clinical observations suggest that stressful events can anticipate AD onset, while stre