Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Geoffrey B Severin"'
Autor:
Harry L T Mobley, Mark T Anderson, Bridget S Moricz, Geoffrey B Severin, Caitlyn L Holmes, Elizabeth N Ottosen, Tad Eichler, Surbhi Gupta, Santosh Paudel, Ritam Sinha, Sophia Mason, Stephanie D Himpsl, Aric N Brown, Margaret Gaca, Christina M Kiser, Thomas H Clarke, Derrick E Fouts, Victor J DiRita, Michael A Bachman
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012495 (2024)
There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal bacteremia. Facultative anaerobic species of the Enterobacterales order are the most common cause of
Externí odkaz:
https://doaj.org/article/790cb40716724b9980c96102427a6fde
Autor:
Geoffrey B. Severin, Miriam S. Ramliden, Kathryne C. Ford, Andrew J. Van Alst, Ram Sanath-Kumar, Kaitlin A. Decker, Brian Y. Hsueh, Gong Chen, Soo Hun Yoon, Lucas M. Demey, Brendan J. O'Hara, Christopher R. Rhoades, Victor J. DiRita, Wai-Leung Ng, Christopher M. Waters
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT A major challenge faced by bacteria is infection by bacteriophage (phage). Abortive infection is one strategy for combating phage in which an infected cell kills itself to limit phage replication, thus protecting neighboring kin. One class o
Externí odkaz:
https://doaj.org/article/0aeb68be07a940b3b442d2253ef708df
Autor:
Geoffrey B. Severin, Miriam S. Ramliden, Kathryne C. Ford, Andrew J. Van Alst, Ram Sanath-Kumar, Kaitlin A. Decker, Brian Y. Hsueh, Soo Hun Yoon, Lucas M. Demey, Brendan J. O’Hara, Christopher R. Rhoades, Victor J. DiRita, Wai-Leung Ng, Christopher M. Waters
A major challenge faced by bacteria is infection by bacteriophage (phage). Abortive infection is one strategy for combating phage in which an infected cell kills itself to limit phage replication, thus protecting neighboring kin. One class of abortiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d26e75fab1055f62b1907425f150e5f
https://doi.org/10.1101/2023.04.04.535582
https://doi.org/10.1101/2023.04.04.535582
Autor:
Marco Agostoni, Alshaé R. Logan-Jackson, Emily R. Heinz, Geoffrey B. Severin, Eric L. Bruger, Christopher M. Waters, Beronda L. Montgomery
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Second messengers are intracellular molecules regulated by external stimuli known as first messengers that are used for rapid organismal responses to dynamic environmental changes. Cyclic di-AMP (c-di-AMP) is a relatively newly discovered second mess
Externí odkaz:
https://doaj.org/article/fc8e0bab3a1241fab4a24b7fe80af0ba
Autor:
Brian Y. Hsueh, Geoffrey B. Severin, Clinton A. Elg, Evan J. Waldron, Abhiruchi Kant, Alex J. Wessel, John A. Dover, Christopher R. Rhoades, Benjamin J. Ridenhour, Kristin N. Parent, Matthew B. Neiditch, Janani Ravi, Eva M. Top, Christopher M. Waters
Publikováno v:
Nat Microbiol
Vibrio cholerae biotype El Tor is perpetuating the longest cholera pandemic in recorded history. The genomic islands VSP-1 and VSP-2 distinguish El Tor from previous pandemic V. cholerae strains. Using a co-occurrence analysis of VSP genes in >200,00
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaeee08c55d27bb767f0db9a65dc564e
https://europepmc.org/articles/PMC9830645/
https://europepmc.org/articles/PMC9830645/
Autor:
Madison G. Walton, Geoffrey B. Severin, Christopher R. Rhoades, Christopher M. Waters, Jeffrey H. Withey
Publikováno v:
Access Microbiology. 4
The human disease cholera, marked by acute, voluminous watery diarrhea, is caused by the gram-negative, aquatic bacterium Vibrio cholerae. All seven cholera pandemics since 1817 were identified as being caused by just 2 of over 155 known V. choleraes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a92db51a5f05b5338f86783c36be10
https://doi.org/10.1099/acmi.ac2021.po0129
https://doi.org/10.1099/acmi.ac2021.po0129
Autor:
Caitlyn L. Holmes, Sara N. Smith, Stephen J. Gurczynski, Geoffrey B. Severin, Lavinia V. Unverdorben, Jay Vornhagen, Harry L. T. Mobley, Michael A. Bachman
Klebsiella pneumoniae is a leading cause of Gram-negative bacteremia, which is a major source of morbidity and mortality worldwide. Gram-negative bacteremia requires three major steps: primary site infection, dissemination to the blood, and bloodstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009949c7a80203d5390bb7af59e35883
https://doi.org/10.1101/2022.03.08.483568
https://doi.org/10.1101/2022.03.08.483568
Publikováno v:
J Bacteriol
Shigella flexneri is an intracellular human pathogen that invades colonic cells and causes bloody diarrhea. S. flexneri evolved from commensal Escherichia coli, and genome comparisons reveal that S. flexneri has lost approximately 20% of its genes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2229d0107192c6a0b1f39aac3f5048
https://doi.org/10.1128/jb.00242-21
https://doi.org/10.1128/jb.00242-21
Autor:
Ben J. Ridenhour, Brian Hsueh, Christopher M. Waters, Rhoades Cr, Wessel Aj, John A. Dover, Elg Ca, Kristin N. Parent, Eva M. Top, Janani Ravi, Geoffrey B. Severin
SUMMARYThe El Tor biotype of Vibrio cholerae is responsible for perpetuating the longest cholera pandemic in recorded history (1961-current). The genomic islands VSP-1 and -2 are two understudied genetic features that distinguish El Tor from previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f44459b0de16a85a75adf0f4733a1c5
https://doi.org/10.1101/2021.03.31.437871
https://doi.org/10.1101/2021.03.31.437871
Autor:
Wai-Leung Ng, Brendan J. O’Hara, Christopher M. Waters, Miriam S. Ramliden, Geoffrey B. Severin
Publikováno v:
Microbial Cyclic Di-Nucleotide Signaling ISBN: 9783030333072
Cyclic dinucleotides are key second messengers essential for bacteria to adapt and thrive in different environments. The recently identified bacterial cyclic dinucleotide second messenger, 3′,3′-cyclic GMP-AMP (cGAMP), was first discovered in Vib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb447db61b30af9f57e787174edfd93d
https://doi.org/10.1007/978-3-030-33308-9_35
https://doi.org/10.1007/978-3-030-33308-9_35