Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Geoffrey A, Mueller"'
Autor:
Brian Walitt, Komudi Singh, Samuel R. LaMunion, Mark Hallett, Steve Jacobson, Kong Chen, Yoshimi Enose-Akahata, Richard Apps, Jennifer J. Barb, Patrick Bedard, Robert J. Brychta, Ashura Williams Buckley, Peter D. Burbelo, Brice Calco, Brianna Cathay, Li Chen, Snigdha Chigurupati, Jinguo Chen, Foo Cheung, Lisa M. K. Chin, Benjamin W. Coleman, Amber B. Courville, Madeleine S. Deming, Bart Drinkard, Li Rebekah Feng, Luigi Ferrucci, Scott A. Gabel, Angelique Gavin, David S. Goldstein, Shahin Hassanzadeh, Sean C. Horan, Silvina G. Horovitz, Kory R. Johnson, Anita Jones Govan, Kristine M. Knutson, Joy D. Kreskow, Mark Levin, Jonathan J. Lyons, Nicholas Madian, Nasir Malik, Andrew L. Mammen, John A. McCulloch, Patrick M. McGurrin, Joshua D. Milner, Ruin Moaddel, Geoffrey A. Mueller, Amrita Mukherjee, Sandra Muñoz-Braceras, Gina Norato, Katherine Pak, Iago Pinal-Fernandez, Traian Popa, Lauren B. Reoma, Michael N. Sack, Farinaz Safavi, Leorey N. Saligan, Brian A. Sellers, Stephen Sinclair, Bryan Smith, Joseph Snow, Stacey Solin, Barbara J. Stussman, Giorgio Trinchieri, Sara A. Turner, C. Stephenie Vetter, Felipe Vial, Carlotta Vizioli, Ashley Williams, Shanna B. Yang, Center for Human Immunology, Autoimmunity, and Inflammation (CHI) Consortium, Avindra Nath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used
Externí odkaz:
https://doaj.org/article/a14b918b7de649e6975c4ac14fdd7aa8
Autor:
Jungki Min, Alexander C. Y. Foo, Scott A. Gabel, Lalith Perera, Eugene F. DeRose, Anna Pomés, Lars C. Pedersen, Geoffrey A. Mueller
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionPet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands.M
Externí odkaz:
https://doaj.org/article/57e29a23f0cd4d248580f8720e11c005
Autor:
Nicole A. LaHood, Jungki Min, Tarun Keswani, Crystal M. Richardson, Kwasi Amoako, Jingjia Zhou, Orlee Marini-Rapoport, Hervé Bernard, Stéphane Hazebrouck, Wayne G. Shreffler, J. Christopher Love, Anna Pomes, Lars C. Pedersen, Geoffrey A. Mueller, Sarita U. Patil
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
In IgE-mediated food allergies, exposure to the allergen activates systemic allergic responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in oral allergen exposure. However, OIT only induces sustained clinical toler
Externí odkaz:
https://doaj.org/article/63cc0678fb644582a854e06feafb31df
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
Externí odkaz:
https://doaj.org/article/c109a504339c4415b58ff9b00065c2cb
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
There have been many attempts to identify common biophysical properties which differentiate allergens from their non-immunogenic counterparts. This review will focus on recent studies which examine two such factors: abundance and stability. Anecdotal
Externí odkaz:
https://doaj.org/article/b2ca0782514240c282a7404b62cf2047
Autor:
Alexander C. Y. Foo, Jacqueline B. Nesbit, Stephen A. Y. Gipson, Eugene F. DeRose, Hsiaopo Cheng, Barry K. Hurlburt, Michael D. Kulis, Edwin H. Kim, Stephen C. Dreskin, Shahzad Mustafa, Soheila J. Maleki, Geoffrey A. Mueller
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:2990-2998
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The development of allergic disease involves the production of IgE antibodies upon allergen exposure in a process called sensitization. IgE binds to receptors on the surface of mast cells and basophils, and subsequent allergen exposure leads to cross
Externí odkaz:
https://doaj.org/article/bfeac76dc576434d9227a6c7d7bf7362
Autor:
Natalya P Degtyareva, Victoria C Placentra, Scott A Gabel, Leszek J Klimczak, Dmitry A Gordenin, Brett A Wagner, Garry R Buettner, Geoffrey A Mueller, Tatyana I Smirnova, Paul W Doetsch
Publikováno v:
Nucleic Acids Res
Mutational signatures discerned in cancer genomes, in aging tissues and in cells exposed to toxic agents, reflect complex processes underlying transformation of cells from normal to dysfunctional. Due to its ubiquitous and chronic nature, redox stres
Autor:
Bradley P, Klemm, Deepa, Singh, Cassandra E, Smith, Allen L, Hsu, Lucas B, Dillard, Juno M, Krahn, Robert E, London, Geoffrey A, Mueller, Mario J, Borgnia, Roel M, Schaaper
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(37)
Levels of the cellular dNTPs, the direct precursors for DNA synthesis, are important for DNA replication fidelity, cell cycle control, and resistance against viruses.
Autor:
Bradley P. Klemm, Deepa Singh, Cassandra E. Smith, Allen L. Hsu, Lucas B. Dillard, Juno M. Krahn, Robert E. London, Geoffrey A. Mueller, Mario J. Borgnia, Roel M. Schaaper
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Levels of the cellular dNTPs, the direct precursors for DNA synthesis, are important for DNA replication fidelity, cell cycle control, and resistance against viruses. Escherichia coli encodes a dGTPase (2′-deoxyguanosine-5′-triphosphate [dGTP] tr